ZYBAN SUMMARY
ZYBAN (bupropion hydrochloride) Sustained-Release Tablets are a non-nicotine aid to smoking cessation. ZYBAN is chemically unrelated to nicotine or other agents currently used in the treatment of nicotine addiction. Initially developed and marketed as an antidepressant (WELLBUTRIN® [bupropion hydrochloride] Tablets and WELLBUTRIN SR® [bupropion hydrochloride] Sustained-Release Tablets), ZYBAN is also chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines. It is (±)-1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride.
ZYBAN is indicated as an aid to smoking cessation treatment.
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ZYBAN NEWS HIGHLIGHTS
Media Articles Related to Zyban (Bupropion)
Nicotine Patch May Be More Helpful Than Bupropion for Adolescent Smoking Cessation
Source: Medscape Primary Care Headlines [2004.08.19]
Actavis Receives Approval Of Generic Wellbutrin XL(R) 300mg In The United States
Source: Depression News From Medical News Today [2008.08.19]
BJOG Release: Using Nicotine Replacement Therapy During Pregnancy
Source: Smoking / Quit Smoking News From Medical News Today [2008.08.21]
Published Studies Related to Zyban (Bupropion)
Randomized, placebo-controlled trial of bupropion for the treatment of methamphetamine dependence. [2008.08.01]
Eight-week, placebo-controlled, double-blind comparison of the antidepressant efficacy and tolerability of bupropion XR and venlafaxine XR. [2008.07.17]
A placebo-controlled trial of bupropion combined with nicotine patch for smoking cessation in schizophrenia. [2008.06.01]
A randomized, double-blind, placebo-controlled study of the effect of sustained-release bupropion on blood pressure in individuals with mild untreated hypertension. [2008.06]
Toward Personalized Therapy for Smoking Cessation: A Randomized Placebo-controlled Trial of Bupropion. [2008.04.02]
Clinical Trials Related to Zyban (Bupropion)
Wellbutrin XL, Major Depressive Disorder and Breast Cancer [Completed]
The Effects of Acute Administration of Bupropion on Neural Substrates Underlying Hedonic Capacity [Completed]
Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation [Completed]
A Preliminary Study of Sustained-Release Bupropion for Smoking Cessation in Bipolar Affective Disorder [Completed]
Chantix & Bupropion for Smoking Cessation [Active, not recruiting]
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