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Zyban (Bupropion Hydrochloride) - Summary

 

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ZYBAN SUMMARY

ZYBAN (bupropion hydrochloride) Sustained-Release Tablets are a non-nicotine aid to smoking cessation. ZYBAN is chemically unrelated to nicotine or other agents currently used in the treatment of nicotine addiction. Initially developed and marketed as an antidepressant (WELLBUTRIN® [bupropion hydrochloride] Tablets and WELLBUTRIN SR® [bupropion hydrochloride] Sustained-Release Tablets), ZYBAN is also chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines. It is (±)-1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride.

ZYBAN is indicated as an aid to smoking cessation treatment.

ZYBAN NEWS HIGHLIGHTS

Media Articles Related to Zyban (Bupropion)

Nicotine Patch May Be More Helpful Than Bupropion for Adolescent Smoking Cessation
Source: Medscape Primary Care Headlines [2004.08.19]

Actavis Receives Approval Of Generic Wellbutrin XL(R) 300mg In The United States
Source: Depression News From Medical News Today [2008.08.19]

BJOG Release: Using Nicotine Replacement Therapy During Pregnancy
Source: Smoking / Quit Smoking News From Medical News Today [2008.08.21]

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Published Studies Related to Zyban (Bupropion)

Randomized, placebo-controlled trial of bupropion for the treatment of methamphetamine dependence. [2008.08.01]

Eight-week, placebo-controlled, double-blind comparison of the antidepressant efficacy and tolerability of bupropion XR and venlafaxine XR. [2008.07.17]

A placebo-controlled trial of bupropion combined with nicotine patch for smoking cessation in schizophrenia. [2008.06.01]

A randomized, double-blind, placebo-controlled study of the effect of sustained-release bupropion on blood pressure in individuals with mild untreated hypertension. [2008.06]

Toward Personalized Therapy for Smoking Cessation: A Randomized Placebo-controlled Trial of Bupropion. [2008.04.02]

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Clinical Trials Related to Zyban (Bupropion)

Wellbutrin XL, Major Depressive Disorder and Breast Cancer [Completed]

The Effects of Acute Administration of Bupropion on Neural Substrates Underlying Hedonic Capacity [Completed]

Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation [Completed]

A Preliminary Study of Sustained-Release Bupropion for Smoking Cessation in Bipolar Affective Disorder [Completed]

Chantix & Bupropion for Smoking Cessation [Active, not recruiting]

more>>

Page last updated: 2008-08-21

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