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Zonegran (Zonisamide) - Published Studies

 
 



Zonegran Related Published Studies

Well-designed clinical trials related to Zonegran (Zonisamide)

Zonisamide: its pharmacology, efficacy and safety in clinical trials. [2012]

Assessment of treatment algorithms including amantadine, metformin, and zonisamide for the prevention of weight gain with olanzapine: a randomized controlled open-label study. [2011.05.17]

Efficacy and safety of adjunctive zonisamide in adult patients with refractory partial-onset epilepsy: a randomized, double-blind, placebo-controlled trial. [2011]

Zonisamide versus topiramate in migraine prophylaxis: a double-blind randomized clinical trial. [2011]

Zonisamide for bipolar disorder, mania or mixed states: a randomized, double blind, placebo-controlled adjunctive trial. [2011]

Zonisamide versus diazepam in the treatment of alcohol withdrawal syndrome. [2010.11]

Placebo-controlled trial of zonisamide for the treatment of alcohol dependence. [2010]

Zonisamide: in Parkinson's disease. [2009.08.01]

Zonisamide: in Parkinson's disease. [2009]

Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study. [2007.08]

Zonisamide and renal calculi in patients with epilepsy: how big an issue? [2007.08]

A double-blind placebo-controlled trial of zonisamide (zonegran) in the treatment of essential tremor. [2007.02]

A double-blind placebo-controlled trial of zonisamide (zonegran) in the treatment of essential tremor. [2007.01.15]

Zonisamide improves motor function in Parkinson disease: a randomized, double-blind study. [2007.01.02]

Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled trial. [2006.12]

Zonisamide as adjunctive therapy for refractory partial seizures. [2006.02]

Zonisamide in the treatment of painful diabetic neuropathy: a randomized, double-blind, placebo-controlled pilot study. [2005.05]

Effect of zonisamide on essential tremor: a pilot crossover study in comparison with arotinolol. [2005.03]

Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures. [2005.01]

Zonisamide clinical trials: European experience. [2004.12]

Randomized, controlled clinical trial of zonisamide as adjunctive treatment for refractory partial seizures. [2004.06]

Zonisamide for weight loss in obese adults: a randomized controlled trial. [2003.04.09]

Zonisamide add-on for drug-resistant partial epilepsy. [2002]

Randomized controlled trial of zonisamide for the treatment of refractory partial-onset seizures. [2001.11.27]

Zonisamide for drug-resistant partial epilepsy. [2000]

Zonisamide for add-on treatment of refractory partial epilepsy: a European double-blind trial. [1993.05]

Well-designed clinical trials possibly related to Zonegran (Zonisamide)

[Role of zonisamid in treating epilepsy, Parkinson disorders and other neurological diseases] [2009.11.30]

Anticonvulsant drugs for pediatric migraine prevention: an evidence-based review. [2009.10]

Anticonvulsant drugs for pediatric migraine prevention: An evidence-based review. [2008.12.10]

Secondary osteoporosis in long-term bedridden patients with cerebral palsy. [2008.06]

Seizure-free outcome in randomized add-on trials of the new antiepileptic drugs. [2007.07]

Seizure-Free Outcome in Randomized Add-on Trials of the New Antiepileptic Drugs. [2007.05.23]

Postoperative seizures: epidemiology, pathology, and prophylaxis. [2003.12]

Developmental and therapeutic pharmacology of antiepileptic drugs. [2000]

Expanding first-line therapy options for children with partial seizures. [2000]

The new antiepileptic drugs: a systematic review of their efficacy and tolerability. [1997.08]

An overview of the efficacy and tolerability of new antiepileptic drugs. [1997]

Other research related to Zonegran (Zonisamide)

A randomized, placebo-controlled study of zonisamide to prevent olanzapine-associated weight gain. [2012]

Assessment of treatment algorithms including amantadine, metformin, and zonisamide for the prevention of weight gain with olanzapine: a randomized controlled open-label study. [2012]

An open pilot study of zonisamide augmentation in major depressive patients not responding to a low dose trial with duloxetine: preliminary results on tolerability and clinical effects. [2011.09.19]

The long-term retention of zonisamide in a large cohort of people with epilepsy at a tertiary referral centre. [2011.09]

Comparative trial of low- and high-dose zonisamide as monotherapy for childhood epilepsy. [2011.09]

Zonisamide versus topiramate in migraine prophylaxis: a double-blind randomized clinical trial. [2011.07]

Drug safety evaluation of zonisamide for the treatment of epilepsy. [2011.07]

Moderate toxic effects following acute zonisamide overdose. [2011.05]

Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors. [2011.05]

Zonisamide-induced long-lasting recovery of dopaminergic neurons from MPTP-toxicity. [2011.04.12]

Our clinical experience with zonisamide in resistant generalized epilepsy syndromes. [2011.03.30]

A pilot open-label trial of zonisamide in Unverricht-Lundborg disease. [2011.02.01]

Zonisamide for migraine prophylaxis in topiramate-intolerant patients: an observational study. [2011.02]

Drug safety evaluation of zonisamide for the treatment of epilepsy. [2011]

Comparative trial of low- and high-dose zonisamide as monotherapy for childhood epilepsy. [2011]

Zonisamide suppresses the tonic phase but not the clonic phase of generalized seizures in developing rats. [2010.12]

Zonisamide in managing impulse control disorders in Parkinson's disease. [2010.10]

Therapeutic effect of a novel anti-parkinsonian agent zonisamide against MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine) neurotoxicity in mice. [2010.09]

Effects of zonisamide in the treatment of alcohol dependence. [2010.09]

Zonisamide ameliorates symptoms of secondary paroxysmal dystonia. [2010.09]

Zonisamide discontinuation due to psychiatric and cognitive adverse events: a case-control study. [2010.08.10]

Zonisamide: aspects in neuroprotection. [2010.08]

Placebo-controlled trial of zonisamide for the treatment of alcohol dependence. [2010.06]

Urolithiasis on the ketogenic diet with concurrent topiramate or zonisamide therapy. [2010.06]

Therapeutic effect of a novel anti-parkinsonian agent zonisamide against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice. [2010.06]

Administration of zonisamide in three cases of dementia with Lewy bodies. [2010.06]

Zonisamide: a new drug for Parkinson's disease. [2010.04]

A prospective audit of adjunctive zonisamide in an everyday clinical setting. [2010.04]

Open label trial of the tolerability and efficacy of zonisamide in the treatment of alcohol dependence. [2010.03]

Flexible dosing of adjunctive zonisamide in the treatment of adult partial-onset seizures: a non-comparative, open-label study (ZEUS). [2010.03]

Zonisamide-induced weight loss in schizophrenia: case series. [2010.03]

[Zonisamide in the preventive treatment of refractory migraine] [2010.02.01]

Neuroprotective effects of zonisamide target astrocyte. [2010.02]

[The discovery of an antiparkinsonian drug, zonisamide] [2010.02]

The antiepileptic drug zonisamide inhibits MAO-B and attenuates MPTP toxicity in mice: clinical relevance. [2010.02]

[Therapeutic drug monitoring of zonisamide] [2010.01]

Zonisamide in the treatment of epilepsy. [2010.01]

Effectiveness and tolerability of zonisamide in children with epilepsy: a retrospective review. [2010.01]

Acute kidney injury caused by zonisamide-induced hypersensitivity syndrome. [2010]

Open label trial of the tolerability and efficacy of zonisamide in the treatment of alcohol dependence. [2010]

Zonisamide in the treatment of epilepsy. [2010]

Zonisamide in West syndrome: an open label study. [2009.12]

Efficacy and tolerability of zonisamide as add-on in brain tumor-related epilepsy: preliminary report. [2009.09]

Zonisamide enhances delta receptor-associated neurotransmitter release in striato-pallidal pathway. [2009.09]

Idiopathic hemifacial spasm responsive to zonisamide: a case report. [2009.07]

Bioequivalence of zonisamide orally dispersible tablet and immediate-release capsule formulations: results from two open-label, randomized-sequence, single-dose, two-period, two-treatment crossover studies in healthy male volunteers. [2009.06]

The impact of zonisamide on weight. A clinical study in 103 patients with epilepsy. [2009.04]

Efficacy and tolerability of zonisamide in idiopathic generalized epilepsy. [2009.03]

Zonisamide for migraine prophylaxis in patients refractory to topiramate. [2009.03]

Zonisamide for essential tremor: an evaluator-blinded study. [2009.02.15]

Zonisamide in children and young adults with refractory epilepsy: an open label, multicenter Italian study. [2009.02]

Open-label, long-term safety study of zonisamide administered to children and adolescents with epilepsy. [2009.01]

Effects of zonisamide on c-Fos expression under conditions of tacrine-induced tremulous jaw movements in rats: a potential mechanism underlying its anti-parkinsonian tremor effect. [2009.01]

The anticonvulsant zonisamide reduces ethanol self-administration by risky drinkers. [2009]

Disposition and safety of zonisamide after intravenous and oral single dose and oral multiple dosing in normal hound dogs. [2008.12]

Predicting possible zonisamide hypersensitivity syndrome. [2008.12]

[Zonisamide as add-on treatment for focal epilepsies. An outcome analysis of 74 patients] [2008.12]

[Preventive treatment of chronic migraine with zonisamide: a study in patients who are refractory or intolerant to topiramate] [2008.11.01]

Effects of zonisamide on isolated head tremor. [2008.11]

Therapeutic role of zonisamide in neuropsychiatric disorders. [2008.09]

Population Estimation Regarding the Effects of Cytochrome P450 2C19 and 3A5 Polymorphisms on Zonisamide Clearance. [2008.08]

Long-term safety and efficacy of zonisamide in patients with refractory partial-onset epilepsy. [2008.08]

Pharmacokinetics and toxicity of zonisamide in cats. [2008.08]

Zonisamide concentrations during pregnancy. [2008.07]

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