NEWS HIGHLIGHTS
Published Studies Related to Zioptan (Tafluprost)
[Intraocular pressure lowering effect of 0.0015% tafluprost as compared to
placebo in patients with normal tension glaucoma: randomized, double-blind,
multicenter, phase III study]. [Article in Japanese] [2010]
CONCLUSION: These results indicate that Tafluprost is clinically useful in the
Efficacy and safety of tafluprost 0.0015% versus latanoprost 0.005% eye drops in
open-angle glaucoma and ocular hypertension: 24-month results of a randomized,
double-masked phase III study. [2010]
open-angle glaucoma or ocular hypertension... CONCLUSIONS: Tafluprost is a new effective and well-tolerated treatment for
A phase II study on the duration and stability of the intraocular
pressure-lowering effect and tolerability of Tafluprost compared with
latanoprost. [2010]
exfoliation glaucoma, or ocular hypertension... CONCLUSIONS: Tafluprost and latanoprost have comparable effects on the extent,
Adjunctive use of tafluprost with timolol provides additive effects for reduction
of intraocular pressure in patients with glaucoma. [2009]
hypertension, uncontrolled by timolol monotherapy... CONCLUSIONS: As adjunctive therapy to timolol, tafluprost achieved a consistently
Efficacy and safety levels of preserved and preservative-free tafluprost are
equivalent in patients with glaucoma or ocular hypertension: results from a
pharmacodynamics analysis. [2008]
analogue with a preservative-free formulation... CONCLUSIONS: THE reduction in IOP achieved by preservative-free tafluprost is
Clinical Trials Related to Zioptan (Tafluprost)
The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucoma [Recruiting]
The objective of this study is to investigate corneal confocal microscopic findings, ocular
signs and symptoms in patients on treatment with the preserved prostaglandin analogue
latanoprost 0. 005% eye drops (Xalatan®) and after the switch to preservative-free
prostaglandin analog tafluprost 0. 0015% eye drops (Taflotan®). Patients who have been using
latanoprost as their prior medication (at least 6 months) and who fulfil all the inclusion
criteria including the specified ocular symptoms and signs, will switch from latanoprost
0. 005% eye drops to the assigned preservative-free tafluprost 0. 0015% eye drops for twelve
(12) months.
Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against Monotherapies [Recruiting]
The purpose of this study is to compare the efficacy and safety of the preservative-free
fixed tafluprost-timolol combination to those of tafluprost and timolol alone. This study
will enroll patients who have ocular hypertension or glaucoma and who are using timolol or
prostaglandin.
The study medication period is 6 months, but the primary evaluation of efficacy is done at 3
months.
Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002 AM1) [Recruiting]
This study will evaluate whether Preservative-Free tafluprost is non-inferior to
Preservative-Free timolol in reducing intra-ocular pressure (IOP) in patients with
open-angle glaucoma or ocular hypertension.
Reports of Suspected Zioptan (Tafluprost) Side Effects
Ocular Hyperaemia (8),
Drug Ineffective (4),
Eye Irritation (4),
Growth of Eyelashes (4),
Cough (4),
Eye Pruritus (4),
Eye Pain (4),
Nasopharyngitis (3),
Headache (3),
Urinary Tract Infection (3), more >>
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