Media Articles Related to Zingo (Lidocaine)
Does Adding Epidural to General Anesthesia Improve Survival in AAA Repair?
Source: Medscape Anesthesiology Headlines [2016.09.19]
Combining epidural and general anesthesia for abdominal aortic aneurysm repair is associated with improved survival and lower risk of complications, according to a recent study. But the associations may not hold up in the real world, other researchers suggest.
Reuters Health Information
Practical Aspects of Using Total Intravenous Anaesthesia
Source: Medscape Anesthesiology Headlines [2016.09.21]
What are the preferred agents for total intravenous anesthesia? For what procedures is it most appropriate? How should it be monitored? Learn the practical approach to TIVA in this article.
Published Studies Related to Zingo (Lidocaine)
Intraoperative systemic lidocaine for pre-emptive analgesics in subtotal
gastrectomy: a prospective, randomized, double-blind, placebo-controlled study. 
lidocaine infusion in patients who underwent subtotal gastrectomy... CONCLUSION: Intravenous lidocaine infusion reduces pain during the postoperative
Efficacy of intraperitoneal and intravenous lidocaine on pain relief after
laparoscopic cholecystectomy. 
infusion for postoperative pain control after laparoscopic cholecystectomy (LC)... CONCLUSIONS: The IP administration of lidocaine and IV lidocaine infusion
Lidocaine/tetracaine peel in topical anesthesia prior to laser-assisted hair
removal: Phase-II and Phase-III study results. 
peel"), which air-dries and can be peeled off 30 min post-application... CONCLUSIONS: After a 30-min application, LT peel was effective and well-tolerated
Transversus abdominis plane block versus perioperative intravenous lidocaine
versus patient-controlled intravenous morphine for postoperative pain control
after laparoscopic colorectal surgery: study protocol for a prospective,
randomized, double-blind controlled clinical trial. 
BACKGROUND: Despite the laparoscopic approach becoming the standard in colorectal
surgery, postoperative pain management for minimally invasive surgery is still
mainly based on strategies that have been established for open surgical
procedures... DISCUSSION: Recognizing the importance of a multimodal approach for perioperative
pain management, we aim to investigate whether a transversus abdominis plane
block delivers superior pain control in comparison to perioperative intravenous
lidocaine and patient-controlled intravenous analgesia with morphine alone.
Intravenous lidocaine for the treatment of background or procedural burn pain. 
CONCLUSIONS: As current clinical evidence is based on only one RCT as
Clinical Trials Related to Zingo (Lidocaine)
Tumescent Lidocaine Maximum Safe mg/kg Dosage [Enrolling by invitation]
This pharmacokinetic clinical trial is a dose ranging study of lidocaine in tumescent local
anesthesia. The goal is to understand the absorption pharmacokinetic of tumescent lidocaine
and to determine an objective (statistical) estimate of the maximum safe mg/kg dosage of
lidocaine in tumescent local anesthesia without liposuction.
Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving [Recruiting]
We propose that the systemic administration of lidocaine following the induction of
cue-induced craving, relative to saline plus cue-induced craving or lidocaine without
cue-induced craving, will block the reconsolidation of cue memories. This will lead to a
reduction in cue-induced craving upon repeated testing as well as subsequent cocaine use and
Lidocaine: Effect of Lidocaine in Chronic Cough [Completed]
People cough in order to clear their airways. Most coughs are caused by viruses and settle
down by themselves, but some people develop persistent coughing which can be anywhere from 8
weeks to several years. This is called chronic cough. People with chronic cough find the
symptom distressing and it can have a major impact on their quality of life. Patients with
chronic cough often report a sensation at the back of their throat which makes them feel an
urge to cough. There is some evidence that Lidocaine (an anaesthetic used during medical
procedures) can suppress a person's cough when given to patients via a nebuliser (a machine
that turns liquid into a fine mist).
It is currently unknown whether using a local anaesthetic, such as Lidocaine, in the form of
a throat spray would successfully suppress a person's cough. A throat spray would be an
easier treatment option in chronic cough patients. Thus, the investigators research aims to
compare cough rates, severity and urge to cough scores between Lidocaine throat spray and
Lidocaine Infusion for Chronic Pain in Opioid Dependent Patients [Recruiting]
Prescription drug abuse represents a major healthcare problem, with treatment costs reaching
billions of dollars annually in the United States alone. Today opioids are commonly
prescribed for chronic non-cancer pain and are only partially effective for short-term pain
relief. Whereas opioids are initially part of the solution for pain, it eventually often
turns to be a problem in patient with chronic pain. Long-term treatment with opioids can be
complicated by development of tolerance, dependency, addiction, abnormal pain sensitivity,
hormonal changes, and immune modulation. Unfortunately, the chronic use of anti-inflammatory
drugs is associated with a marked increase in adverse effects.
The purpose of this study is to determine whether systemic administration of lidocaine
provides effective pain relief in opioid dependent chronic pain patients. Investigators
intend to demonstrate that lidocaine infusion can improve pain relief and physical function
in opioid dependent patients, thus improving compliance and patient satisfaction, which may
potentially help wean patients off narcotics. The long-term goal of this proposal is to
decrease opioid dependence in chronic pain patients by using lidocaine infusion.
Intra-arterial Lidocaine for Pain Control Post Uterine Fibroid Embolization [Recruiting]
Uterine artery embolization (UAE) is a minimally invasive treatment for women with
symptomatic fibroids. It is similar to hysterectomy in term of satisfaction and symptoms
improvement, with fewer complications and at lower cost. However, the majority of women
undergoing UFE experience important pain after the procedure despite optimal analgesia, with
one third reporting pain equal or worse than labor. Pain is the more common cause of
prolonged hospital stay or readmission. There is need for a simple, efficient way to reduce
For this prospective randomized study, the hypothesis is that an anesthetic drug, lidocaine,
injected in the uterine arteries diminishes pain post-UFE. Patients will be randomized in 3
groups: control, lidocaine injected during embolization, and lidocaine injected after
embolization. Pain will be evaluated using a validated scale at 4h and 24h
post-intervention. Hospital length-of-stay and total narcotic dose administered will be
evaluated in the three groups.
This is the first Canadian study evaluating lidocaine use for pain control in UFE patients.
Results will be transferable to clinical practice, considering the use of lidocaine is
simple and cost is negligible. It could have a great impact on pain management in women
undergoing UFE in all practice settings.