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Yasmin (Ethinyl Estradiol) - Summary



Cigarette smoking increases the risk of serious cardiovascular side effects from oral contraceptive use. This risk increases with age and with heavy smoking (15 or more cigarettes per day) and is quite marked in women over 35 years of age. Women who use oral contraceptives should be strongly advised not to smoke.



(drospirenone and ethinyl estradiol)

YASMIN provides an oral contraceptive regimen consisting of 21 active film coated tablets each containing 3.0 mg of drospirenone and 0.030 mg of ethinyl estradiol and 7 inert film coated tablets.

YASMIN is indicated for the prevention of pregnancy in women who elect to use an oral contraceptive.
See all Yasmin indications & dosage >>


Media Articles Related to Yasmin (Ethinyl Estradiol)

Domestic violence deters contraception
Source: Abortion News From Medical News Today [2015.04.02]
Domestic violence takes many forms. The control of a woman's reproductive choices by her partner is one of them.

'15 million unwanted pregnancies' created by low contraception in 35 poorer countries
Source: Abortion News From Medical News Today [2015.02.05]
Some 90% of the 16.7 million unwanted pregnancies across a third of the world's population every year are due to a failure to use modern contraception, study suggests.

Research reveals more than half of young women who have abortions were using contraception when they fell pregnant
Source: Abortion News From Medical News Today [2014.04.30]
Reproductive health charity Marie Stopes UK has launched the findings of the first research in the UK into the contraceptive use of women aged 16-24 having one or more abortions.

Adolescent women 'more likely to have unsafe sex' if obese
Source: Sexual Health / STDs News From Medical News Today [2015.07.01]
Obese adolescent women were found less likely to use contraception than their peers with healthy weights, with those that did use contraception less likely to use it consistently.

Female cystic fibrosis patients need more contraceptive guidance, study finds
Source: Cystic Fibrosis News From Medical News Today [2015.05.11]
As life span for once-deadly disease increases, unplanned and mistimed pregnancies are commonOnly half of women with cystic fibrosis (CF) report using contraception and frequently apt to become...

more news >>

Published Studies Related to Yasmin (Ethinyl Estradiol)

An overview of four studies of a continuous oral contraceptive (levonorgestrel 90 mcg/ethinyl estradiol 20 mcg) on premenstrual dysphoric disorder and premenstrual syndrome. [2012]
and premenstrual syndrome (PMS)... CONCLUSIONS: These data, although not consistent, indicate that continuous LNG/EE

Ethinyl estradiol and levonorgestrel pharmacokinetics with a low-dose transdermal contraceptive delivery system, AG200-15: a randomized controlled trial. [2011.11.29]
BACKGROUND: This study evaluated the ethinyl estradiol (EE) and levonorgestrel (LNG) pharmacokinetic profiles of AG200-15, a transdermal contraceptive delivery system, compared with a combination oral contraceptive (COC) containing EE 35 mcg and norgestimate 250 mcg... CONCLUSIONS: EE and LNG daily exposure during AG200-15 treatment was within the range reported for a low-dose COC. The daily EE dose with AG 200-15 was equivalent to a 30-mcg COC and was safe and well tolerated. Copyright (c) 2011 Elsevier Inc. All rights reserved.

Effect of extended-cycle regimen with an oral contraceptive containing 30 mcg ethinylestradiol and 2 mg dienogest on bleeding patterns, safety, acceptance and contraceptive efficacy. [2011.08]
BACKGROUND: The present study compared the efficacy and safety of a combined oral contraceptive containing 30 mcg ethinylestradiol and 2 mg dienogest (EE/DNG) in conventional and extended-cycle regimen over 1 year of treatment... CONCLUSIONS: Extended-cycle use of EE/DNG was effective and mostly well tolerated, appearing to be a favorable option for women who need or wish to omit the pill-free interval. Copyright (c) 2011 Elsevier Inc. All rights reserved.

Effect of ticagrelor on the pharmacokinetics of ethinyl oestradiol and levonorgestrel in healthy volunteers. [2011.08]
BACKGROUND: Cytochrome P450 3 A is involved in ticagrelor and ethinyl oestradiol/levonorgestrel metabolism; so a potential drug-drug interaction may occur. OBJECTIVES: To assess: ticagrelor effects on ethinyl oestradiol/levonorgestrel pharmacokinetics, endogenous sex hormone levels; ethinyl oestradiol/levonorgestrel effects on ticagrelor pharmacokinetics; tolerability of ticagrelor + ethinyl oestradiol/levonorgestrel... CONCLUSIONS: Ticagrelor co-administration with ethinyl oestradiol/levonorgestrel increased ethinyl oestradiol exposure by approximately 20%, with no effect on levonorgestrel pharmacokinetics. No clinically relevant effect on contraceptive efficacy is expected with ethinyl oestradiol/levonorgestrel and ticagrelor co-administration.

Premenstrual dysphoric disorder symptom cluster improvement by cycle with the combined oral contraceptive ethinylestradiol 20 mcg plus drospirenone 3 mg administered in a 24/4 regimen. [2011.07]
BACKGROUND: A combined oral contraceptive comprising ethinylestradiol (EE) 20 mcg/drospirenone 3 mg in a 24/4 regimen has been clinically shown to alleviate the symptoms associated with premenstrual dysphoric disorder (PMDD). However, previous studies did not report data according to cycle-by-cycle improvement... CONCLUSION: Ethinylestradiol 20 mcg/drospirenone 3 mg 24/4 improved commonly recognizable PMDD symptom clusters relating to negative emotions, food cravings and water retention-related symptoms to a significantly greater extent than placebo during all three cycles of treatment. Copyright (c) 2011 Elsevier Inc. All rights reserved.

more studies >>

Clinical Trials Related to Yasmin (Ethinyl Estradiol)

Yasmin 20 Cycle Control - Yasmin 20 Versus Mercilon in Healthy Female Volunteers [Completed]

Effects of Counseling on the Continuation Rates and Compliance for Newly Prescribed Oral Contraceptives (Yasmin´┐Ż or Any Other Oral Contraceptives (OC) [Recruiting]
This study is a prospective, company-sponsored, non-interventional cohort study of up to 5000 patients in European countries and countries in Middle East who are newly prescribed any available OC. Patients will be followed up approximately 6 months after initial visit. Selection of Study Population: Women can be enrolled after decision for treatment with Yasmin or any other OC has been made. Physicians should consult the full prescribing information for the respective OC before enrolling patients and familiarize themselves with the safety information in the product package label.

Yasmin Post Marketing Surveillance [Recruiting]

Effect of Angeliq on Blood Pressure (BP) in Postmenopausal Hypertensive Women [Completed]
The objective of the study is to evaluate the effects of Angeliq on BP over a period of 8 weeks in postmenopausal women who may benefit from hormone replacement therapy (HRT) for the relief of vasomotor symptoms and who have hypertension.

Investigate Impact of Yasmin vs Microgynon on Hemostasis Parameters in Healthy Women [Completed]
The objective of this study was to investigate the impact of the oral contraceptive YASMIN (containing: drospirenone 3 mg/ethinyl estradiol 30 mcg) in comparison with the oral contraceptive MICROGYNON (containing: levonorgestrel 150 mcg/ethinyl estradiol 30mcg) on factors of blood coagulation and fibrinolysis in female subjects

more trials >>

Reports of Suspected Yasmin (Ethinyl Estradiol) Side Effects

Pain (6403)Injury (5334)Anxiety (3576)Emotional Distress (3357)Pulmonary Embolism (2965)Deep Vein Thrombosis (2812)General Physical Health Deterioration (1709)Gallbladder Disorder (1683)Cholecystitis Chronic (1660)Anhedonia (1336)more >>


Based on a total of 25 ratings/reviews, Yasmin has an overall score of 5.48. The effectiveness score is 8.88 and the side effect score is 6.08. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.

Yasmin review by 32 year old female patient

Overall rating:  
Effectiveness:   Highly Effective
Side effects:   No Side Effects
Treatment Info
Condition / reason:   birth control, acne control
Dosage & duration:   1/day (dosage frequency: 1/day) for the period of 4 years
Other conditions:   acne, hypothyroid
Other drugs taken:   synthroid
Reported Results
Benefits:   Controlled acne very well when taken continuously. Eliminated PMS symptoms. Prevented pregnancy. Experienced minimal monthly bleeding.
Side effects:   I did not experience any side effects.
Comments:   1 pill per day in the morning with food. Take 3 days off (placebo pills) before starting a new pack rather than a whole week. Take two pills the next day if a pill is missed.


Yasmin review by 26 year old female patient

Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Severe Side Effects
Treatment Info
Condition / reason:   Birth Control
Dosage & duration:   i don't remember (dosage frequency: once a day) for the period of 2.5 months
Other conditions:   Lazy thyroid
Other drugs taken:   none
Reported Results
Benefits:   Well, I had no babies. Also, skin was a bit clearer and breasts got about half a cup bigger (but that came with the rest of my body getting bigger, too).
Side effects:   I gained 10 lbs in just a couple months, I had period munchies all the time, and could always eat. I felt uncomfortable turning down food and seemed to have a never-ending appetite. This would subside during the sugar pill week. I suspect, but am not sure, that Yasmin also gave me some vaginal dryness. I had frequent painful sex, would get raw very easily, and actually got a tear inside my vagina from sex. If we went at it twice a day it seemed I would need a day or two break just to recover. (None of this has happened before, so the doctor suggested I move to a lower dose pill.)
Comments:   Take once a day at the same time everyday.


Yasmin review by 19 year old female patient

Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Extremely Severe Side Effects
Treatment Info
Condition / reason:   Birth Control
Dosage & duration:   1 pill/day for 21 days taken once a day for the period of a year and a half
Other conditions:   none
Other drugs taken:   n/a
Reported Results
Benefits:   By taking Yasmin I did not get pregnant, as it did act as a proper birth control method. However the side effects outweighed the benefits and I was forced to switch to a new form of birth control. I would NEVER recommend this type of birth control.
Side effects:   Severe depression, mood swings, weight gain, longer period, yeast infections, and numerous other effects.
Comments:   1 pill daily for 21 days and then a week break.

See all Yasmin reviews / ratings >>

Page last updated: 2015-07-01

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