BOX WARNING
Cigarette smoking increases the risk of serious cardiovascular side effects from oral contraceptive use. This risk increases with age and with heavy smoking (15 or more cigarettes per day) and is quite marked in women over 35 years of age. Women who use oral contraceptives should be strongly advised not to smoke.
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YASMIN SUMMARY
YASMIN 28 TABLETS
(drospirenone and ethinyl estradiol)
YASMIN provides an oral contraceptive regimen consisting of 21 active film coated tablets each containing 3.0 mg of drospirenone and 0.030 mg of ethinyl estradiol and 7 inert film coated tablets.
YASMIN is indicated for the prevention of pregnancy in women who elect to use an oral contraceptive.
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NEWS HIGHLIGHTSMedia Articles Related to Yasmin (Ethinyl Estradiol)
US funding revamps African contraceptive drive (AFP)
Source: Y! Health News Search RSS Feed [2009.11.18]
AFP - A new 12 million dollar family planning drive launched here Wednesday highlights how Obama administration funding has revamped a contraception drive in Africa and developing states, UN officials said, noting a sharp turnaround from the Bush era.
Terrence Higgins Trust Welcomes Department Of Health Nursing Degree Announcement, UK
Source: HIV / AIDS News From Medical News Today [2009.11.15]
HIV and sexual health charity Terrence Higgins Trust has welcomed the announcement by the Department of Health that all new nurses will be educated to degree level from 2013. Terrence Higgins Trust (THT) currently employs nurses who work in Chlamydia screening programmes for young people, HIV testing clinics and clinics that offer contraception services and screening for sexually transmitted infections.
Published Studies Related to Yasmin (Ethinyl Estradiol)
A randomized controlled trial of a low-dose combined oral contraceptive containing 3 mg drospirenone plus 20 microg ethinylestradiol in the treatment of acne vulgaris: lesion counts, investigator ratings and subject self-assessment. [2009.09]
OBJECTIVE: To assess the efficacy of a combined oral contraceptive (COC) containing 3 mg drospirenone (drsp) plus 20 microg ethinylestradiol (EE) administered in 24 days of active treatment followed by a four-day hormone-free interval (24/4 regimen) compared with placebo for the treatment of moderate acne vulgaris... CONCLUSION: The 3 mg drsp/20 microg EE COC administered in a 24/4 regimen significantly reduced acne lesions.
Effects of metformin versus ethinyl-estradiol plus cyproterone acetate on ambulatory blood pressure monitoring and carotid intima media thickness in women with the polycystic ovary syndrome. [2009.06]
OBJECTIVE: To compare the effects of metformin versus an antiandrogenic contraceptive pill on ambulatory blood pressure monitoring (ABPM) and carotid intima media thickness (CIMT) in women with polycystic ovary syndrome (PCOS).Treatment with either Diane(35) Diario or metformin improved CIMT mean values.
Efficacy of a combined oral contraceptive containing 0.030 mg ethinylestradiol/2 mg dienogest for the treatment of papulopustular acne in comparison with placebo and 0.035 mg ethinylestradiol/2 mg cyproterone acetate. [2009.04]
BACKGROUND: Acne is a multifactorial disease characterized by androgenic stimulation of sebaceous glands. Therefore, combined oral contraceptives (COCs) containing anti-androgenic progestogens are suitable candidates for acne treatment. This study aimed to show that a COC containing the anti-androgen dienogest (DNG) is superior to placebo and not inferior to a COC containing the potent anti-androgen cyproterone acetate (CPA) in improving mild to moderate acne... CONCLUSION: EE/DNG was superior to placebo, in spite of the prominent placebo effects, and as effective as EE/CPA in the treatment of mild to moderate acne, thus proving a valid option for the treatment of acne in women seeking oral contraception.
[Efficacy and safety of drospirenone-ethinylestradiol on contraception in healthy chinese women: a multicenter randomized controlled trial] [2009.01]
OBJECTIVE: To evaluate the contraception efficacy, mode of bleeding, side effects and other positive effects of drospirenone-ethinylestradiol (Yasmin) in healthy Chinese women... CONCLUSIONS: Both Yasmin and desogestrel have good efficacy on contraception and similar modes of menstrual bleeding. Yasmin is better than desogestrel in terms of weight control and premenstrual syndrome of oral contraceptive.
The effects of two monophasic oral contraceptives containing 30 mcg of ethinyl estradiol and either 2 mg of chlormadinone acetate or 0.15 mg of desogestrel on lipid, hormone and metabolic parameters. [2009.01]
BACKGROUND: This study was conducted to compare the effects of two monophasic oral contraceptives (OCs) containing ethinyl estradiol (EE) 30 mcg+either chlormadinone acetate (CMA) 2 mg (Belara) or 0.15 mg desogestrel (Marvelon) on lipid, hormone and other relevant metabolic parameters... CONCLUSIONS: Both low-dose monophasic OCs had comparable effects on lipid, hormone and metabolic parameters during six cycles of treatment in healthy female subjects. There was some evidence of a beneficial effect on atherogenic cardiovascular risk markers, which was slightly more pronounced with EE 30 mcg+CMA 2 mg.
Clinical Trials Related to Yasmin (Ethinyl Estradiol)
Yasmin 20 Cycle Control - Yasmin 20 Versus Mercilon in Healthy Female Volunteers [Completed]
Effect of Angeliq on Blood Pressure (BP) in Postmenopausal Hypertensive Women [Completed]
The objective of the study is to evaluate the effects of Angeliq on BP over a period of 8
weeks in postmenopausal women who may benefit from hormone replacement therapy (HRT) for the
relief of vasomotor symptoms and who have hypertension.
Investigate Impact of Yasmin vs Microgynon on Hemostasis Parameters in Healthy Women [Completed]
The objective of this study was to investigate the impact of the oral contraceptive YASMIN
(containing: drospirenone 3 mg/ethinyl estradiol 30 mcg) in comparison with the oral
contraceptive MICROGYNON (containing: levonorgestrel 150 mcg/ethinyl estradiol 30mcg) on
factors of blood coagulation and fibrinolysis in female subjects
Effects of Counseling on the Continuation Rates and Compliance for Newly Prescribed Oral Contraceptives (YasminŽ or Any Other Oral Contraceptives (OC)) [Recruiting]
This study is a prospective, company-sponsored, non-interventional cohort study of up to
5000 patients in the following countries Albania, Bosnia and Herzegovina, Kenya, Macedonia,
Hungary, Middle East (Kingdom of Saudi Arabia, Gulf, Levant, Egypt), Moldova, Russia, Turkey
who are newly prescribed Yasmin or any other available OC. Patients will be followed up
approximately 6 months after initial visit. Selection of Study Population Women can be
enrolled after decision for treatment with Yasmin or any other OC has been made. Physicians
should consult the full prescribing information for the respective OC before enrolling
patients and familiarize themselves with the safety information in the product package
label.
Regulatory Post Marketing Surveillance Study on YAZ [Recruiting]
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PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 14 ratings/reviews, Yasmin has an overall score of 5.50. The effectiveness score is 9.43 and the side effect score is 6.43. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
| | Yasmin review by 32 year old female patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Highly Effective |
| Side effects: | | No Side Effects | | |
Treatment Info |
| Condition / reason: | | birth control, acne control |
| Dosage & duration: | | 1/day (dosage frequency: 1/day) for the period of 4 years |
| Other conditions: | | acne, hypothyroid |
| Other drugs taken: | | synthroid | | |
Reported Results |
| Benefits: | | Controlled acne very well when taken continuously. Eliminated PMS symptoms. Prevented pregnancy. Experienced minimal monthly bleeding. |
| Side effects: | | I did not experience any side effects. |
| Comments: | | 1 pill per day in the morning with food. Take 3 days off (placebo pills) before starting a new pack rather than a whole week. Take two pills the next day if a pill is missed. |
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| | Yasmin review by 26 year old female patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Highly Effective |
| Side effects: | | Severe Side Effects | | |
Treatment Info |
| Condition / reason: | | Birth Control |
| Dosage & duration: | | i don't remember (dosage frequency: once a day) for the period of 2.5 months |
| Other conditions: | | Lazy thyroid |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | Well, I had no babies.
Also, skin was a bit clearer and breasts got about half a cup bigger (but that came with the rest of my body getting bigger, too). |
| Side effects: | | I gained 10 lbs in just a couple months, I had period munchies all the time, and could always eat. I felt uncomfortable turning down food and seemed to have a never-ending appetite. This would subside during the sugar pill week.
I suspect, but am not sure, that Yasmin also gave me some vaginal dryness. I had frequent painful sex, would get raw very easily, and actually got a tear inside my vagina from sex. If we went at it twice a day it seemed I would need a day or two break just to recover. (None of this has happened before, so the doctor suggested I move to a lower dose pill.) |
| Comments: | | Take once a day at the same time everyday. |
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| | Yasmin review by 22 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Highly Effective |
| Side effects: | | Severe Side Effects | | |
Treatment Info |
| Condition / reason: | | Contraception |
| Dosage & duration: | | 1 pill a day, 21 days a month taken once a day, 21 days a month for the period of About a year |
| Other conditions: | | None |
| Other drugs taken: | | None | | |
Reported Results |
| Benefits: | | Didn't get pregnant
Clear skin
Light periods |
| Side effects: | | Vaginal dryness
Loss of sex drive
cervical erosion (doctors, tests and scans comfirmed the pill caused this)
Painful intercourse
Dry hair
Dry skin
Dry, burning eyes (very dry- now have a chronic condition)
Hair loss
Night sweats
Hot flashes
Decrease in skin lustre and elasticity |
| Comments: | | Lost interest in sex rapidly, if I was ever aroused (very rare) I couldn't achieve an orgasm, every part of my body seemed to dry out and subsequently age a bit and in the case of my eyes this drying and ageing process was pretty severe. Doctors were baffled as to why I'd ended up with such dry eyes at such a young age, said they weren't sure what caused it but said it normally happens to menopausal or elderly women (I was 20-21 at the time). Now looking back I realise that the dry eyes match with a lot of the other symptoms I was experiencing at the time, many of which are normally symptoms of the menopause/ageing. Considering these symptoms have now either completely disappeared or improved since stopping the use of hormonal birth control methods (I now use the copper IUD), I believe they may well have been linked Yasmin. Yasmin is one scary pill- I came off it worried that I was prematurely going through the menopause and that I would never be able to enjoy painless, bloodless, pleasurable sex again. |
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Page last updated: 2009-11-18
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