XYLOCAINE SUMMARY
Xylocaine®
(lidocaine HCl Injection, USP)
Xylocaine®
(lidocaine HCl and epinephrine Injection, USP)
For Infiltration and Nerve Block
Xylocaine (lidocaine HCl Injection, USP) is a sterile non-pyrogenic solution of an antiarrhythmic agent administered intravenously by direct injection.
Xylocaine administered intravenously is specifically indicated in the acute management of ventricular arrhythmias such as those occurring in relation to acute myocardial infarction, or during cardiac manipulation, such as cardiac surgery.
|
NEWS HIGHLIGHTSMedia Articles Related to Xylocaine (Lidocaine)
Children With Refractory Ventricular Arrhythmias Benefit From Minimally Invasive VATS-LCSD
Source: Cardiovascular / Cardiology News From Medical News Today [2013.05.09]
Inherited ventricular arrhythmias are an important cause of morbidity and sudden cardiac death in children who have structurally normal hearts. Despite conventional medical therapy, some of these children remain symptomatic with recurrent life-threatening arrhythmias, syncope, or frequent discharges from implantable cardioverter defibrillators (ICDs)...
Published Studies Related to Xylocaine (Lidocaine)
Cervical lidocaine for IUD insertional pain: a randomized controlled trial. [2012]
intracervical 2% lidocaine gel for pain relief with IUD insertion... CONCLUSION: Topical or intracervical 2% lidocaine gel prior to IUD insertion does
Treatment for postoperative wound pain in gynecologic laparoscopic surgery:
topical lidocaine patches. [2012]
CONCLUSIONS: Topical lidocaine patches at the laparoscopic port sites reduced
Lidocaine/tetracaine patch (Rapydan) for topical anaesthesia before arterial
access: a double-blind, randomized trial. [2012]
non-inferior to subcutaneous local anaesthetic... CONCLUSIONS: Both the lidocaine/tetracaine patch and subcutaneous injection of
Intravenous lidocaine for the treatment of background or procedural burn pain. [2012]
CONCLUSIONS: As current clinical evidence is based on only one single
Systemic lidocaine to improve postoperative quality of recovery after ambulatory
laparoscopic surgery. [2012]
outpatient laparoscopic surgery... CONCLUSIONS: Systemic lidocaine improves postoperative quality of recovery in
Clinical Trials Related to Xylocaine (Lidocaine)
Comparison of the Total Dose and Efficacy of Two Lidocaine Concentrations Needed for Cutaneous Surgery Local Anesthesia [Completed]
The purpose of the study will be to demonstrate whether Mohs micrographic surgery can be
performed with a lower total dose of local anesthesia (and greater patient safety) when using
0. 5% lidocaine with 1: 200,000 epinephrine versus 1% lidocaine with 1: 100,000 epinephrine.
J-Tip® Jet Injection of 1% Buffered Lidocaine or Saline Versus 4% Lidocaine Cream Before Venipuncture or IV Insertion [Not yet recruiting]
To measure and compare pain associated with venipuncture and peripheral intravenous catheter
insertion among pediatric emergency department patients randomized to treatment with one of
three different pain-reduction strategies: J-Tip® jet injection of 1% buffered lidocaine,
J-Tip® jet injection of sterile saline, or application of 4% lidocaine topical cream. The
investigators hypothesize that J-Tip® jet injection of 1% buffered lidocaine will provide
superior local anesthesia compared to saline or lidocaine cream.
Lidocaine and Ketamine in Abdominal Surgery [Recruiting]
This study is being done to determine if combined infusions of lidocaine and ketamine is
better than a lidocaine or ketamine infusion alone, or to placebo in improving recovery
after abdominal hysterectomy. Participants will be randomized into one of four groups.
Evaluations will be done through walking tests, pain and fatigue questionnaires and blood
tests.
A Study to Characterize the Phenotype in Patients With Morton's Neuroma and to Explore the Effect of Local Administration of Xylocaine (Lidocaine) [Recruiting]
To characterize the phenotype in patients with Morton's neuroma and to explore the effect of
local administration of Xylocaine (lidocaine)
Lidocaine Lubricant in Pediatric Urethral Catheterization [Completed]
In Emergency Departments (ED) across the nation there is renewed interest in finding ways to
alleviate the pain and discomfort associated with many of the procedures that children must
undergo. In a policy by the American Academy of Pediatrics, a nationally recognized advocate
for children, physicians are urged to advocate for child-specific research in pain management
and the effective use of pain medication to ensure compassionate and competent management of
pain. (AAP Statement, 2001) Pediatric urethral catheterizations are one such procedure in
which children experience significant pain.(11) In present care, children over 2 months of
age do not routinely receive intervention for urethral catheterization related anxiety and
pain, and, anecdotal reports suggest that most require physical restraint to complete the
procedure. Lidocaine is an anesthetic agent that provides relief from pain during many
commonly performed ED procedures. Intraurethral Lidocaine has been shown to decrease pain
associated with urethral catheter placement in cystograms, however, Lidocaine is not
routinely used for urethral catheterizations in the CHOA ED.
This study aims to investigate the potential use of Lidocaine as an anesthetic agent during
urethral catheterization of children. Recently, two specific studies were performed
investigating the use of Lidocaine to decrease discomfort associated with urethral
catheterization. Using the strengths of both previously published studies, our study will use
Lidocaine both topically and instilled into the urethra. Investigators plan to perform a
prospective three-arm double-blinded randomized clinical trial investigating the
effectiveness of Lidocaine jelly as a analgesic when used as a lubricant for urinary
catheterization. Investigators aim to demonstrate that Lidocaine used as a lubricant
anesthetic for urethral catheterization will provide a safe, time-efficient, and relatively
easy way to decrease pediatric pain in the emergency department setting.
Reports of Suspected Xylocaine (Lidocaine) Side Effects
Anaphylactic Shock (18),
Convulsion (13),
Angioedema (9),
Toxicity TO Various Agents (9),
Drug Rash With Eosinophilia and Systemic Symptoms (9),
Tachycardia (8),
Eosinophil Count Increased (8),
Toxic Skin Eruption (8),
Loss of Consciousness (7),
Malaise (6), more >>
|
