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Xolair (Omalizumab) - Published Studies

 
 



Xolair Related Published Studies

Well-designed clinical trials related to Xolair (Omalizumab)

Omalizumab and the risk of malignancy: results from a pooled analysis. [2012]

A randomized, placebo-controlled, dose-ranging study of single-dose omalizumab in patients with H1-antihistamine-refractory chronic idiopathic urticaria. [2011.09]

Efficacy and safety of omalizumab in patients with chronic urticaria who exhibit IgE against thyroperoxidase. [2011.07]

Omalizumab in severe allergic asthma inadequately controlled with standard therapy: a randomized trial. [2011.05.03]

Persistency of response to omalizumab therapy in severe allergic (IgE-mediated) asthma. [2011.05]

Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children. [2011.03.17]

Effects of omalizumab on changes in pulmonary function induced by controlled cat room challenge. [2011.02]

A randomized, placebo-controlled, dose-ranging study of single-dose omalizumab in patients with H1-antihistamine-refractory chronic idiopathic urticaria. [2011]

Omalizumab decreases IgE production in patients with allergic (IgE-mediated) asthma; PKPD analysis of a biomarker, total IgE. [2011]

Omalizumab therapy in atopic dermatitis: depletion of IgE does not improve the clinical course - a randomized, placebo-controlled and double blind pilot study. [2010.12]

Omalizumab-induced decrease of FcvarepsilonRI expression in patients with severe allergic asthma. [2010.11]

Omalizumab in children with inadequately controlled severe allergic (IgE-mediated) asthma. [2010.06]

Regulation of Syk kinase and FcRbeta expression in human basophils during treatment with omalizumab. [2010.04]

Effects of omalizumab on basophil and mast cell responses using an intranasal cat allergen challenge. [2010.04]

Effect of pretreatment with omalizumab on the tolerability of specific immunotherapy in allergic asthma. [2010.02]

Safety of anti-IgE treatment with omalizumab in children with seasonal allergic rhinitis undergoing specific immunotherapy simultaneously. [2010.02]

Omalizumab for pediatric asthma. [2010]

Omalizumab therapy in atopic dermatitis: depletion of IgE does not improve the clinical course - a randomized, placebo-controlled and double blind pilot study. [Article in English, German] [2010]

Effects of omalizumab on basophil and mast cell responses using an intranasal cat allergen challenge. [2010]

Effect of omalizumab on peripheral blood eosinophilia in allergic asthma. [2010]

Safety of anti-IgE treatment with omalizumab in children with seasonal allergic rhinitis undergoing specific immunotherapy simultaneously. [2010]

Omalizumab for the treatment of exacerbations in children with inadequately controlled allergic (IgE-mediated) asthma. [2009.12]

Relationship between pretreatment specific IgE and the response to omalizumab therapy. [2009.12]

Efficacy and safety of omalizumab in an Asian population with moderate-to-severe persistent asthma. [2009.11]

Adding omalizumab to the therapy of adolescents with persistent uncontrolled moderate--severe allergic asthma. [2009.10]

The size of the disease relevant IgE antibody fraction in relation to 'total-IgE' predicts the efficacy of anti-IgE (Xolair) treatment. [2009.10]

Safety of anti-IgE treatment with omalizumab in children with seasonal allergic rhinitis undergoing specific immunotherapy simultaneously. [2009.09.02]

Efficacy of omalizumab in cat-allergic patients with moderate-to-severe persistent asthma. [2009.09]

Combination of omalizumab and specific immunotherapy is superior to immunotherapy in patients with seasonal allergic rhinoconjunctivitis and co-morbid seasonal allergic asthma. [2009.02]

Asthma symptom re-emergence after omalizumab withdrawal correlates well with increasing IgE and decreasing pharmacokinetic concentrations. [2009.01]

Add-on omalizumab improves day-to-day symptoms in inadequately controlled severe persistent allergic asthma. [2008.05]

Allergen skin tests and free IgE levels during reduction and cessation of omalizumab therapy. [2008.02]

Basophil histamine release decreases during omalizumab therapy in allergic asthmatics. [2008]

Effect of omalizumab on the need for rescue systemic corticosteroid treatment in patients with moderate-to-severe persistent IgE-mediated allergic asthma: a pooled analysis. [2007.10]

Omalizumab (Xolair) in children with seasonal allergic rhinitis: leukotriene release as a potential in vitro parameter to monitor therapeutic effects. [2007.09]

Combination treatment with omalizumab and rush immunotherapy for ragweed-induced allergic rhinitis: Inhibition of IgE-facilitated allergen binding. [2007.09]

Safety of anti-immunoglobulin E therapy with omalizumab in allergic patients at risk of geohelminth infection. [2007.02]

[Omalizumab as a therapeutic option in atopic eczema : Current evidence and potential benefit.] [2007.02]

[Omalizumab as a therapeutic option in atopic eczema : Current evidence and potential benefit.] [2007.01.20]

Effect of omalizumab treatment on peripheral eosinophil and T-lymphocyte function in patients with allergic asthma. [2006.06]

Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis. [2006.01]

Effect of omalizumab on adenosine 5'-monophosphate responsiveness in subjects with allergic asthma. [2006]

Anti-IgE (omalizumab) inhibits late-phase reactions and inflammatory cells after repeat skin allergen challenge. [2005.09]

Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE. [2005.03]

Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. [2004.09.15]

Effects of omalizumab, a humanized monoclonal anti-IgE antibody, on nasal reactivity to allergen and local IgE synthesis. [2004.09]

Cost-effectiveness analysis of omalizumab in adults and adolescents with moderate-to-severe allergic asthma. [2004.08]

Efficacy and tolerability of anti-immunoglobulin E therapy with omalizumab in patients with concomitant allergic asthma and persistent allergic rhinitis: SOLAR. [2004.07]

Efficacy and tolerability of anti-immunoglobulin E therapy with omalizumab in patients with poorly controlled (moderate-to-severe) allergic asthma. [2004.07]

Efficacy and safety of a recombinant anti-immunoglobulin E antibody (omalizumab) in severe allergic asthma. [2004.04]

Predicting response to omalizumab, an anti-IgE antibody, in patients with allergic asthma. [2004.04]

Exhaled nitric oxide in children with asthma receiving Xolair (omalizumab), a monoclonal anti-immunoglobulin E antibody. [2004.04]

Omalizumab inhibits allergen challenge-induced nasal response. [2004.03]

Omalizumab rapidly decreases nasal allergic response and FcepsilonRI on basophils. [2004.02]

Omalizumab treatment downregulates dendritic cell FcepsilonRI expression. [2003.12]

Urinary leukotriene E4 levels in children with allergic rhinitis treated with specific immunotherapy and anti-IgE (Omalizumab). [2003.10]

Evaluation of long-term safety of the anti-IgE antibody, omalizumab, in children with allergic asthma. [2003.08]

Omalizumab, an anti-IgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis. [2003.08]

Omalizumab is effective in the long-term control of severe allergic asthma. [2003.08]

Immunological and clinical changes in allergic asthmatics following treatment with omalizumab. [2003.05]

Omalizumab improves asthma-related quality of life in patients with severe allergic asthma. [2003.02]

Omalizumab, a recombinant humanized anti-IgE antibody, reduces asthma-related emergency room visits and hospitalizations in patients with allergic asthma. [2003.01]

The anti-IgE antibody omalizumab improves asthma-related quality of life in patients with allergic asthma. [2002.11]

Omalizumab improves asthma-related quality of life in children with allergic asthma. [2002.11]

Omalizumab provides long-term control in patients with moderate-to-severe allergic asthma. [2002.07]

The effect of omalizumab on nasal allergic inflammation. [2002.07]

Effect of omalizumab on symptoms of seasonal allergic rhinitis: a randomized controlled trial. [2001.12.19]

The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics. [2001.08]

Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma. [2001.08]

Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab). [2001.08]

Well-designed clinical trials possibly related to Xolair (Omalizumab)

Evaluating the minimally important difference of the urticaria activity score and other measures of disease activity in patients with chronic idiopathic urticaria. [2012]

A randomized, double-blind, placebo-controlled trial of anti-IgE for chronic rhinosinusitis. [2010.09]

Decreases in human dendritic cell-dependent T(H)2-like responses after acute in vivo IgE neutralization. [2010.04]

A randomized, double-blind, placebo-controlled trial of anti-IgE for chronic rhinosinusitis. [2010]

Decreases in human dendritic cell-dependent T(H)2-like responses after acute in vivo IgE neutralization. [2010]

Geohelminth infections: a review of the role of IgE and assessment of potential risks of anti-IgE treatment. [2008.04]

The economic value of anti-IgE in severe persistent, IgE-mediated (allergic) asthma patients: adaptation of INNOVATE to Sweden. [2006.09]

The co-seasonal application of anti-IgE after preseasonal specific immunotherapy decreases ocular and nasal symptom scores and rescue medication use in grass pollen allergic children. [2004.09]

Effect of anti-immunoglobulin E on nasal inflammation in patients with seasonal allergic rhinoconjunctivitis. [2004.07]

The effect of anti-IgE treatment on in vitro leukotriene release in children with seasonal allergic rhinitis. [2002.11]

Efficacy of combination treatment with anti-IgE plus specific immunotherapy in polysensitized children and adolescents with seasonal allergic rhinitis. [2002.02]

Other research related to Xolair (Omalizumab)

Oral corticosteroid sparing with omalizumab in severe allergic (IgE-mediated) asthma patients. [2011.11]

Development of the Asthma Control Composite outcome measure to predict omalizumab response. [2011.09]

Omalizumab decreases IgE production in patients with allergic (IgE-mediated) asthma; PKPD analysis of a biomarker, total IgE. [2011.08]

Omalizumab in patients with severe asthma: the XCLUSIVE study. [2011.07.08]

[The efficacy of shortening an administration period with omalizumab]. [2011.05]

Safety of omalizumab in asthma. [2011.05]

Clinical benefits of 7 years of treatment with omalizumab in severe uncontrolled asthmatics. [2011.05]

Changes of immunomodulatory cytokines associated with omalizumab therapy for severe persistent asthma. [2011.04]

Omalizumab: Anti-IgE therapy in allergy. [2011.04]

Cost-utility of add-on omalizumab in difficult-to-treat allergic asthma in Italy. [2011.03]

Xolair in asthma therapy: an overview. [2011.02]

Beneficial effects of treatment with anti-IgE antibodies (Omalizumab) in a patient with severe asthma and negative skin-prick test results. [2011.01]

Omalizumab for the treatment of severe persistent allergic asthma in children aged 6-11 years. [2011]

Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children. [2011]

Effects of omalizumab on changes in pulmonary function induced by controlled cat room challenge. [2011]

Effectiveness of omalizumab in reducing corticosteroid burden in patients with moderate to severe persistent allergic asthma. [2010.12]

Omalizumab therapy in atopic dermatitis: depletion of IgE does not improve the clinical course - a randomized, placebo-controlled and double blind pilot study. [2010.07.30]

One year treatment with omalizumab is effective and well tolerated in Japanese Patients with moderate-to-severe persistent asthma. [2010.06]

Effects of omalizumab in patients with food allergy. [2010.01]

Immunological effects of omalizumab in chronic urticaria: a case report. [2010]

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