WESTCORT SUMMARY
Westcort®
(hydrocortisone valerate cream)
Cream, 0.2%
Westcort® (hydrocortisone valerate cream) Cream, 0.2% contains hydrocortisone valerate, 11,21-dihydroxy-17-[(1-oxopentyl)oxy]-(11β)-pregn-4-ene-3,20-dione, a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.
Westcort Cream is a medium potency corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses in adult patients.
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NEWS HIGHLIGHTSMedia Articles Related to Westcort (Hydrocortisone Topical)
hydrocortisone valerate, Westcort
Source: MedicineNet Diaper Rash Specialty [2005.12.13]
Title: hydrocortisone valerate, Westcort
Category: Medications
Created: 4/4/1999 6:03:00 PM
Last Editorial Review: 12/13/2005
Published Studies Related to Westcort (Hydrocortisone Topical)
Randomized controlled trial comparing the effectiveness of 308-nm excimer laser alone or in combination with topical hydrocortisone 17-butyrate cream in the treatment of vitiligo of the face and neck. [2008.11]
BACKGROUND: Vitiligo is a pigmentary disorder which may have disfiguring consequences. Its treatment remains a challenge. OBJECTIVES: We designed a parallel-group randomized controlled trial to compare the effectiveness of 308-nm excimer laser alone or in combination with topical hydrocortisone 17-butyrate cream in patients with vitiligo unresponsive to previous treatment with topical steroids or narrow-band ultraviolet (UV) B phototherapy... CONCLUSIONS: Recalcitrant vitiligo of the face and neck may benefit from the combination of excimer laser phototherapy with topical hydrocortisone 17-butyrate cream.
Randomized controlled trial comparing the effectiveness of 308-nm excimer laser alone or in combination with topical hydrocortisone 17-butyrate cream in the treatment of vitiligo of the face and neck. [2008.08.19]
Background Vitiligo is a pigmentary disorder which may have disfiguring consequences... Conclusions Recalcitrant vitiligo of the face and neck may benefit from the combination of excimer laser phototherapy with topical hydrocortisone 17-butyrate cream.
1% Hydrocortisone ointment is an effective treatment of pruritus ani: a pilot randomized controlled crossover trial. [2007.12]
BACKGROUND: Pruritus ani (PA) is a common condition which is difficult to treat in the absence of obvious predisposing factors. There is paucity of evidence-based guidelines on the treatment of this condition. We examined whether 1% hydrocortisone ointment is an effective treatment for PA... CONCLUSION: A short course of mild steroid ointment is an effective treatment for PA.
Topical treatment of acute otitis externa: clinical comparison of an antibiotics ointment alone or in combination with hydrocortisone acetate. [2007.09]
The study was designed to investigate the potential contribution of hydrocortisone acetate to the efficacy and safety of an antibiotics ointment in the treatment of acute otitis externa (AOE). In a double-blind study 151 patients with a unilateral acute bacterial otitis externa were randomized either to receive an ointment with polymyxin-B sulfate (7,500 I.E./g) + bacitracin (300 I.E./g) alone (AB) or the same antibiotic ointment with 10 mg hydrocortisone acetate/g ointment (AB + HC)...
The comparative effects of tacrolimus and hydrocortisone in adult atopic dermatitis: an immunohistochemical study. [2007.02]
BACKGROUND: While many studies have demonstrated the efficacy and safety of tacrolimus ointment in the treatment of atopic dermatitis (AD), only a few have investigated the effects of tacrolimus on inflammatory cells and their cytokine gene expression in patients with AD. OBJECTIVES: To characterize further the immunophenotype of infiltrating cells and the production of certain cytokines before and after treatment with topical tacrolimus and hydrocortisone butyrate... CONCLUSIONS: Tacrolimus not only inhibits T-lymphocyte proliferation and cytokine production, but also plays an important role in the IL-12-induced shift from a T-helper (Th) 2 to a Th1 cytokine profile that characterizes the development of chronic AD. Tacrolimus also demonstrates wider pharmacodynamic effects than hydrocortisone.
Clinical Trials Related to Westcort (Hydrocortisone Topical)
Efficacy Study of Low-Dose Hydrocortisone Treatment for Fibromyalgia [Completed]
This study is based on clinical findings that some patients with fibromyalgia have a tendency
towards lower levels of the stress hormone cortisol. The hypothesis to be tested in this
study is that the administration of a very low-dose of cortisol which has no side effects
corrects this deficiency and results in an improvement of symptoms
Metabolic Effects of Acute Cortisol Withdrawal in Adrenal Failure [Completed]
Effects of adrenal steroids is generelly drawn from studies of hypercortisolism. The effects
of physiological cortisol substitution and withdrawal is studied and related to the clinical
syndrome of adrenal insufficiency.
Correlation Salivary Cortisol and Free Serum Cortisol to Total Serum Cortisol in MICU Septic Shock [Recruiting]
The purpose of the study is:
- to correlate salivary cortisol to free serum cortisol (as salivary cortisol is
considered to be almost complete free cortisol) and,
- to correlate free serum cortisol to total serum cortisol levels
Both in patients with septic shock (severe sepsis requiring vasopressors).
We believe that:
- total serum cortisol does not correlate with free serum cortisol in patient with septic
shock and,
- that salivary cortisol correlates with free serum cortisol and can be used to determine
the level of free serum cortisol.
Hair Cortisol and the Risk of Acute Myocardial Infarction [Recruiting]
Aim of the study:
To evaluate whether hair cortisol levels are elevated in patients admitted with acute MI
compared to controls.
Study steps:
1. Introduction of the study to the participants and inform consent signing
2. Collection of clinical and demographic data
3. Scalp hair sampling- samples will be sent for laboratory analysis
4. Analysis of the results
Does Concurrent Hydrocortisone With Venlafaxine XR Speed Antidepressant Response? [Active, not recruiting]
The primary purpose of this study is to examine whether IV hydrocortisone can speed up the
time required for Venlafaxine XR to work.
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