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Votrient (Pazopanib Hydrochloride) - Published Studies

 
 



Votrient Related Published Studies

Well-designed clinical trials related to Votrient (Pazopanib)

Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma. [2011.06]

Pazopanib in renal cell carcinoma. [2010.12.15]

A phase I study of the pharmacokinetic and safety profiles of oral pazopanib with a high-fat or low-fat meal in patients with advanced solid tumors. [2010.12]

Pazopanib: in advanced renal cell carcinoma. [2010.10.01]

Phase II, open-label study of pazopanib or lapatinib monotherapy compared with pazopanib plus lapatinib combination therapy in patients with advanced and recurrent cervical cancer. [2010.08.01]

Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. [2010.02.20]

Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma. [2010.01.20]

(Pre-)clinical pharmacology and activity of pazopanib, a novel multikinase angiogenesis inhibitor. [2010]

Pazopanib in renal cell carcinoma. [2010]

Pazopanib: in advanced renal cell carcinoma. [2010]

Well-designed clinical trials possibly related to Votrient (Pazopanib)

Multikinase inhibitors in metastatic renal cell carcinoma: indirect comparison meta-analysis. [2011.06]

Major clinical research advances in gynecologic cancer 2009. [2009.12]

Other research related to Votrient (Pazopanib)

Reversible posterior leukoencephalopathy syndrome induced by pazopanib. [2012]

A multiinstitutional phase 2 trial of pazopanib monotherapy in advanced anaplastic thyroid cancer. [2012]

Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials. [2012]

A randomized, phase II study of pazopanib in castrate-sensitive prostate cancer: a University of Chicago Phase II Consortium/Department of Defense Prostate Cancer Clinical Trials Consortium study. [2012]

A phase I pharmacokinetic and safety evaluation of oral pazopanib dosing administered as crushed tablet or oral suspension in patients with advanced solid tumors. [2012]

A randomized, phase II study of pazopanib in castrate-sensitive prostate cancer: a University of Chicago Phase II Consortium/Department of Defense Prostate Cancer Clinical Trials Consortium study. [2011.10.18]

Nursing considerations with pazopanib therapy: focus on metastatic renal cell carcinoma. [2011.10.01]

Anti-angiogenic effects of the receptor tyrosine kinase inhibitor, pazopanib, on choroidal neovascularization in rats. [2011.09]

A phase I pharmacokinetic and safety evaluation of oral pazopanib dosing administered as crushed tablet or oral suspension in patients with advanced solid tumors. [2011.08.03]

Pazopanib synergizes with docetaxel in the treatment of bladder cancer cells. [2011.07]

Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes. [2011.06.20]

Health-related quality of life in patients with advanced renal cell carcinoma receiving pazopanib or placebo in a randomised phase III trial. [2011.06.18]

Pazopanib: a new multiple tyrosine kinase inhibitor in the therapy of metastatic renal cell carcinoma and other solid tumors. [2011.04]

The risk of hand foot skin reaction to pazopanib, a novel multikinase inhibitor: a systematic review of literature and meta-analysis. [2011.03.11]

Pazopanib: the newest tyrosine kinase inhibitor for the treatment of advanced or metastatic renal cell carcinoma. [2011.03.05]

Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis. [2011.01.01]

Nursing considerations with pazopanib therapy: focus on metastatic renal cell carcinoma. [2011]

An evaluation of the drug interaction potential of pazopanib, an oral vascular endothelial growth factor receptor tyrosine kinase inhibitor, using a modified Cooperstown 5+1 cocktail in patients with advanced solid tumors. [2010.11]

New advancements and developments in treatment of renal cell carcinoma: focus on pazopanib. [2010.10.05]

A Phase II, open-label study evaluating pazopanib in patients with recurrent ovarian cancer. [2010.10]

Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study. [2010.10]

Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study. [2010.09.17]

Phase II trial of pazopanib (GW786034), an oral multi-targeted angiogenesis inhibitor, for adults with recurrent glioblastoma (North American Brain Tumor Consortium Study 06-02). [2010.08]

The vascular endothelial growth factor receptor tyrosine kinase inhibitors vatalanib and pazopanib potently induce apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo. [2010.07.01]

Phase II proof-of-concept study of pazopanib monotherapy in treatment-naive patients with stage I/II resectable non-small-cell lung cancer. [2010.07.01]

Effect of pazopanib on tumor microenvironment and liposome delivery. [2010.06]

Pazopanib: an oral multitargeted tyrosine kinase inhibitor for use in renal cell carcinoma. [2010.06]

Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism. [2010.04.27]

Pazopanib: Clinical development of a potent anti-angiogenic drug. [2010.04.22]

Potent preclinical impact of metronomic low-dose oral topotecan combined with the antiangiogenic drug pazopanib for the treatment of ovarian cancer. [2010.04]

Bridging the gap between cytotoxic and biologic therapy with metronomic topotecan and pazopanib in ovarian cancer. [2010.04]

Plasma cytokine and angiogenic factor profiling identifies markers associated with tumor shrinkage in early-stage non-small cell lung cancer patients treated with pazopanib. [2010.03.15]

Phase I study of pazopanib in combination with weekly paclitaxel in patients with advanced solid tumors. [2010]

A phase I study of the pharmacokinetic and safety profiles of oral pazopanib with a high-fat or low-fat meal in patients with advanced solid tumors. [2010]

Phase II, open-label study of pazopanib or lapatinib monotherapy compared with pazopanib plus lapatinib combination therapy in patients with advanced and recurrent cervical cancer. [2010]

Pazopanib: therapeutic developments. [2009.12]

Pazopanib: an antiangiogenic drug in perspective. [2009.11]

Pazopanib for the treatment of renal cell carcinoma and other malignancies. [2009.09]

Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043). [2009.07.01]

Phase I trial of pazopanib in patients with advanced cancer. [2009.06.15]

Suppression and regression of choroidal neovascularization by the multitargeted kinase inhibitor pazopanib. [2009.04]

Pazopanib, a VEGF receptor tyrosine kinase inhibitor for cancer therapy. [2008.12]

Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. [2008.08.14]

Other possibly related research studies

Molecular targeted therapy of advanced hepatocellular carcinoma beyond sorafenib. [2010.09]

[Treatment with oral agents for breast cancer] [2010.07]

Novel Targeted therapy for advanced renal carcinoma: trials in progress. [2010.09]

Systemic therapy for metastatic renal cell carcinoma in treatment naive patients: a risk-based approach. [2010.10]

Inhibiting the VEGF-VEGFR pathway in angiosarcoma, epithelioid hemangioendothelioma, and hemangiopericytoma/solitary fibrous tumor. [2010.07]

[Antiangionic drugs in soft tissue sarcoma] [2010.06]

Targeting angiogenesis with multitargeted tyrosine kinase inhibitors in the treatment of non-small cell lung cancer. [2010]

New therapeutic strategies for renal cell carcinoma. [2010.01]

Current status of vascular endothelial growth factor inhibition in age-related macular degeneration. [2010.06]

Recent advances and future directions in the management of metastatic renal cell carcinoma. [2010.03]

[Management of metastatic HER2-positive breast cancer: present and future] [2010.03]

Plethora of agents, plethora of targets, plethora of side effects in metastatic renal cell carcinoma. [2010.08]

Molecular basis for the treatment of renal cell carcinoma. [2010.01]

Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action? [2010.03]

VEGF signalling inhibition-induced proteinuria: Mechanisms, significance and management. [2010.01]

Gateways to clinical trials. [2009.10]

Impact of anti-angiogenic treatments on metastatic renal cell carcinoma. [2009.12]

Angiogenesis inhibitors in the management of breast cancer. [2010.02]

Tyrosine kinase inhibitors and the thyroid. [2009.12]

Anti-angiogenesis agents in metastatic or recurrent cervical cancer. [2010.02]

Gateways to clinical trials. [2009.07]

Response to antiangiogenesis therapy in a patient with advanced adult-type testicular granulosa cell tumor. [2009.08]

New treatment approaches in renal cell carcinoma. [2009.11]

Metastatic Renal Cell Carcinoma: Recent Advances in the Targeted Therapy Era. [2009.09.08]

Emerging pharmacologic therapies for wet age-related macular degeneration. [2009]

[Chemotherapy for breast cancer refractory to anthracycline, taxane or trastuzumab] [2009.05]

Systemic therapy of advanced urothelial cancer. [2009.08]

Vascular endothelial growth factor-targeted therapy in metastatic renal cell carcinoma. [2009.05.15]

VEGF inhibitors for the treatment of neovascular age-related macular degeneration. [2009.05]

Targeted therapies in metastatic renal cancer in 2009. [2009.05]

Tumoral angiogenesis and breast cancer. [2009.03]

Targeted therapy in the treatment of metastatic renal cell cancer. [2009]

Anti-angiogenic targets in the treatment of advanced renal cell carcinoma. [2008.12]

Signaling inhibitors in metastatic renal cell carcinoma. [2008.09]

[Systemic therapy of metastasizing renal cell carcinoma] [2008.10]

Novel drugs for renal cell carcinoma. [2008.10]

Current and emerging targeted therapies for metastatic breast cancer. [2011.10.17]

Targeted therapy for advanced renal cell cancer (RCC): a Cochrane systematic review of published randomised trials. [2011.11]

Second-line therapy for refractory renal-cell carcinoma. [2011.09.21]

Indirect treatment comparison of bevacizumab + interferon-alpha-2a vs tyrosine kinase inhibitors in first-line metastatic renal cell carcinoma therapy. [2011]

[Renal carcinoma and fatigue: which challenge in the era of antiangiogenic drugs?]. [2011.10.01]

Current systemic management of metastatic renal cell carcinoma - first line and second line therapy. [2011.09]

Predictive factors of response to treatment in patients with metastatic renal cell carcinoma: new evidence. [2011.06]

Future directions of mammalian target of rapamycin (mTOR) inhibitor therapy in renal cell carcinoma. [2011.03]

[Treatment of metastatic renal cell carcinoma]. [2011.04]

Antiangiogenic agents in combination with chemotherapy in patients with advanced non-small cell lung cancer. [2011.05]

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