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Cardiovascular Risk
- NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use. Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk. (See WARNINGS.)
- Voltaren® (diclofenac sodium enteric-coated tablets) is contraindicated for the treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery (see WARNINGS).
Gastrointestinal Risk
- NSAIDs cause an increased risk of serious gastrointestinal adverse events including inflammation, bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events. (See WARNINGS).
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VOLTAREN SUMMARY
Voltaren®
Voltaren® (diclofenac sodium enteric-coated tablets), is a benzene-acetic acid derivative. Voltaren is available as Delayed-Release (enteric-coated) Tablets of 25 mg (yellow), 50 mg (light brown), and 75 mg (light pink) for oral administration. The chemical name is 2-[(2,6-dichlorophenyl)amino] benzeneacetic acid, monosodium salt.
Voltaren® (diclofenac sodium enteric-coated tablets), is indicated:
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For relief of signs and symptoms of osteoarthritis
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For relief of signs and symptoms of rheumatoid arthritis
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For acute or long-term use in the relief of signs and symptoms of ankylosing spondylitis
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VOLTAREN NEWS HIGHLIGHTS Media Articles Related to Voltaren (Diclofenac)
Pharmos Announces Clinical Results From Phase 2a Trial Of Topical Diclofenac NanoEmulsion Cream
Source: Clinical Trials / Drug Trials News From Medical News Today [2008.11.20]
diclofenac and misoprostol, Arthrotec
Source: MedicineNet meloxicam Specialty [2005.12.13]
APR Applied Pharma Research And Fidia Farmaceutici Receive IND Approval From FDA For A New NSAID Matrix Patch Product
Source: Clinical Trials / Drug Trials News From Medical News Today [2008.11.19]
Published Studies Related to Voltaren (Diclofenac)
Diclofenac sodium and occlusal splint therapy in TMJ osteoarthritis: a randomized controlled trial. [2008.10]
Diclofenac sodium 3% gel in the treatment of actinic keratoses postcryosurgery. [2008.07]
Misoprostol effects on diclofenac-induced cardiorenal changes in salt-sensitive patients with hypertension: the MEDIC Study. [2008.07]
Role of diclofenac in reducing post-endoscopic retrograde cholangiopancreatography pancreatitis. [2008.07]
Relieving perineal pain after perineorrhaphy by diclofenac rectal suppositories: a randomized double-blinded placebo controlled trial. [2008.06]
Clinical Trials Related to Voltaren (Diclofenac)
Study to Compare the Pharmacokinetics of IV Diclofenac Sodium (2 Doses)Versus Oral Diclofenac Potassium [Completed]
Assess Platelet Function and Safety After Administration of Injectable Diclofenac Compared to Ketorolac and Aspirin in Adult Male Volunteers [Completed]
Diclofenac Patch for Treatment of Mild to Moderate Ankle Sprain [Active, not recruiting]
Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis [Completed]
Efficacy and Safety of Diclofenac Sodium Gel (DSG) in Knee Osteoarthritis [Completed]
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VOLTAREN PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 4 ratings/reviews, Voltaren has an overall score of 7. The effectiveness score is 7.50 and the side effect score is 9.50. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
| | Voltaren review by 55 year old female patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Highly Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | bursitis and tennis elbow |
| Dosage & duration: | | 100mg taken one daily for the period of 30 days |
| Other conditions: | | rosacea on face |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | I experienced almost immediate relief of both bursitis in my left thigh and tennis elbow in my right aarm. I also had a strained muscle in lower back area which I also experienced relief from. The bursitis had been bothering me for quite some time (8mths)and mainly at nighttime when I was lying down in bed. I found it difficult to get comfortable and often used a hot water bottle to soothe it. |
| Side effects: | | Just after taking the pill (with food) I felt a bit dopey in the head which lasted for up to an hour, and sometimes a slight nausea (but not often). |
| Comments: | | Take with a large glass of water (i must say I did not notice this instruction until now). Take 1 tablet daily (with food) when required to relieve pain and inflammation. Swallow whole. Do not crush or chew. |
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| | Voltaren review by 24 year old female patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Moderately Effective |
| Side effects: | | No Side Effects | | |
Treatment Info |
| Condition / reason: | | eryhema nodosum |
| Dosage & duration: | | 50mg taken when ever pain occurred for the period of 1 week |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | Reduced pain caused by erythema, ability to carry out day to day activities without too much discomfort. Though tiredness was on of the side effects of the problem this could not be resolved with drugs, though blood tests did show whether the situation was improving or not. |
| Side effects: | | None were experienced at the time. there are side affects, but as i didn't really take the drug unless i couldn't cope this did not really seem to affect me. I tried to deal with the pain so that i could monitor if i was beginning to feel better or not. |
| Comments: | | Gentle exercise was encouraged to keep the circulation going. Keeping the erythema affected are rested, by keeping it resting up when sitting down or lying down with a cushion to aid. When swelling occurred anti-inflammatory medication and pain killers were useful in giving some relief. |
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| | Voltaren review by 24 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Moderately Effective |
| Side effects: | | No Side Effects | | |
Treatment Info |
| Condition / reason: | | eryhema nodosum |
| Dosage & duration: | | 50mg taken when ever pain occurred for the period of 1 week |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | Reduced pain caused by erythema, ability to carry out day to day activities without too much discomfort. Though tiredness was on of the side effects of the problem this could not be resolved with drugs, though blood tests did show whether the situation was improving or not. |
| Side effects: | | None were experienced at the time. there are side affects, but as i didn't really take the drug unless i couldn't cope this did not really seem to affect me. I tried to deal with the pain so that i could monitor if i was beginning to feel better or not. |
| Comments: | | Gentle exercise was encouraged to keep the circulation going. Keeping the erythema affected are rested, by keeping it resting up when sitting down or lying down with a cushion to aid. When swelling occurred anti-inflammatory medication and pain killers were useful in giving some relief. |
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Page last updated: 2008-11-20
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