DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Visken (Pindolol) - Summary

 
 



VISKEN SUMMARY

Visken®

Visken® (pindolol), a synthetic beta-adrenergic receptor blocking agent with intrinsic sympathomimetic activity is 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol.

Visken® (pindolol) is indicated in the management of hypertension. It may be used alone or concomitantly with other antihypertensive agents, particularly with a thiazide-type diuretic.



See all Visken indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Visken (Pindolol)

Yoga Improves Quality of Life in Pulmonary Hypertension
Source: Medscape Critical Care Headlines [2016.04.29]
Adults with pulmonary arterial hypertension could derive some relief from yoga, results from a preliminary study suggest. The 12-week program eased anxiety and depression, among other measures.
Medscape Medical News

RA: Hypertension, High LDL Often Missed or Undertreated
Source: Medscape Rheumatology Headlines [2016.04.25]
Patients with rheumatoid arthritis are likely to need more intensive monitoring and treatment of cardiovascular risk factors, but often receive less.
Medscape Medical News

Healthy diet could lower hypertension risk for women with gestational diabetes
Source: Diabetes News From Medical News Today [2016.04.19]
Researchers have found that the long-term risk of high blood pressure that is caused by pregnancy-related diabetes could be reduced by following a healthy diet.

Pulmonary Hypertension
Source: MedicineNet Fainting Specialty [2016.03.30]
Title: Pulmonary Hypertension
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 3/30/2016 12:00:00 AM

High Blood Pressure (Hypertension) Quiz: Test Your Medical IQ
Source: MedicineNet Nosebleed Specialty [2016.01.05]
Title: High Blood Pressure (Hypertension) Quiz: Test Your Medical IQ
Category: MedicineNet Quiz
Created: 2/9/2011 12:56:00 PM
Last Editorial Review: 1/5/2016 2:12:26 PM

more news >>

Published Studies Related to Visken (Pindolol)

Can we really accelerate and enhance the selective serotonin reuptake inhibitor antidepressant effect? A randomized clinical trial and a meta-analysis of pindolol in nonresistant depression. [2011.07]
CONCLUSIONS: Present findings represent further evidence of the acceleration and enhancement of efficacy with pindolol administered together with SSRIs, displaying a quicker and more pronounced decrease of symptoms in patients with nonresistant major depressive disorder. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00931775. (c) Copyright 2011 Physicians Postgraduate Press, Inc.

Pindolol augmentation enhances response outcomes in first depressive episodes. [2009.07]
Effectiveness of Pindolol addition to SSRIs is still a matter of debate.

Glomerular filtration rate after tramadol, parecoxib and pindolol following anaesthesia and analgesia in comparison with morphine in dogs. [2009.01]
OBJECTIVE: To compare the effects of morphine, parecoxib, tramadol and a combination of parecoxib, tramadol and pindolol on nociceptive thresholds in awake animals and their effect on glomerular filtration rate (GFR) in dogs subjected to 30 minutes of anesthesia. ANIMALS: Eight adult mixed breed experimental dogs. STUDY DESIGN: Randomized, controlled trial... CONCLUSION: Tramadol and parecoxib (either alone or in combination) can increase nociceptive thresholds in awake dogs and have minimal effects on renal perfusion in normotensive dogs subjected to anaesthesia.

Paroxetine with pindolol augmentation: A double-blind, randomized, placebo-controlled study in depressed in-patients. [2008.02]
Pindolol, a 5-HT1A autoreceptor antagonist, given in combination with selective serotonin reuptake inhibitors (SSRIs), may enhance and/or accelerate the therapeutic efficacy of SSRIs. Fifty patients, meeting ICD-10 criteria for major depressive disorder or bipolar depression, were enrolled in our randomized, placebo-controlled, double-blind trial...

Noradrenergic activity is associated with response to pindolol in aggressive Alzheimer's disease patients. [2004.06]
Loss of noradrenergic (NE) neurones in the locus ceruleus and compensatory changes in NE activity have been described in Alzheimer's disease (AD), but have never been linked to treatment. The hypothesis of this study was that central NE responsivity would predict aggression response to treatment with a NE medication, pindolol...

more studies >>

Clinical Trials Related to Visken (Pindolol)

EScitalopram PIndolol ONset of Action [Terminated]
The main purpose of this study is to determine whether the antidepressant response of escitalopram 30mg/day or escitalopram 20mg/day + pindolol, a beta blocker, is different (faster) compared to a standard dose of escitalopram 20mg/day.

Trial of Pindolol Augmentation in Venlafaxine Treated Patients With Major Depression [Terminated]
This study investigates the hypothesis that pindolol can accelerate the response to antidepressants in patients with major depression treated with venlafaxine.

Citalopram Versus Citalopram Plus Pindolol in Major Depressive Disorder [Completed]
The purpose of this study is to examine whether the speed of the clinical antidepressant action of citalopram can be accelerated by administering double doses of pindolol (15 mg/day, tid) which presumably should lead to increased 5-HT1A autoreceptor occupancy.

Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine) [Completed]
MDMA (3,4-Methylenedioxymethamphetamine, "Ecstasy") produces tachycardia, hypertension, hyperthermia, and other acute adverse effects. Ecstasy use has also been associated with rare cardio- and cerebrovascular complications. The role of beta-blockers in the treatment of cardiovascular and adverse effects of MDMA is unknown.

Comparison of the Pharmacokinetics of Three Generic Medications and Their Respective Brand Preparations [Recruiting]
Generic describes a pharmaceutical product that does not have a brand name or trademark. Generic medications should be the equivalent of brand medications. Only their price should be different. The active ingredient of the generic medication has to be within a window of 80 to 125% of the original in the blood. There are reports that this standard is not always followed after the medication has been on the market. Indeed, it was observed that some patients previously stable on original medications relapsed when switched to a generic. Several factors could account for this problem. Such problems have been reported for Pindolol, Quetiapine, and Trazodone. Some properties of specific brands of the generics and the original brands will be examined for these three medications. The three original medications used in this study are the Visken, the Seroquel, and the Desyrel. The three generics are the Teva-pindolol, the Teva-Quetiapine, and the Teva-Trazodone. They are all available on the Canadian market by prescription.

more trials >>


Page last updated: 2016-04-29

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2015