Vicodin (Hydrocodone Bitartrate / Acetaminophen) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The most frequently reported adverse reactions include: lightheadedness, dizziness, sedation, nausea and vomiting. These effects seem to be more prominent in ambulatory than in nonambulatory patients and some of these adverse reactions may be alleviated if the patient lies down.

Other adverse reactions include:

Central Nervous System

Drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, mood changes.

Gastrointestinal System

Prolonged administration of VICODIN Tablets may produce constipation.

Genitourinary System

Ureteral spasm, spasm of vesical sphincters and urinary retention have been reported with opiates.

Respiratory Depression

Hydrocodone bitartrate may produce dose-related respiratory depression by acting directly on the brain stem respiratory center. (see OVERDOSAGE).

Special Senses

Cases of hearing impairment or permanent loss have been reported predominantly in patients with chronic overdose.

Dermatological

Skin rash, pruritus.

The following adverse drug events may be borne in mind as potential effects of acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis.

Potential effects of high dosage are listed in the OVERDOSAGE section.

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO VICODIN

Possible Vicodin side effects / adverse reactions in 20 year old female

Reported by a individual with unspecified qualification from United States on 2007-01-12

Patient: 20 year old female

Reactions: Malaise

Adverse event resulted in: death

Suspect drug(s):
Benadryl
    Dosage: 2 ultratabs once, oral
    Administration route: Oral
    Indication: Insomnia
    Start date: 2006-12-09
    End date: 2006-12-09

Vicodin
    Indication: Pain

Possible Vicodin side effects / adverse reactions in 32 year old male

Reported by a individual with unspecified qualification from United States on 2007-01-25

Patient: 32 year old male

Reactions: Confusional State, Head Injury, Intentional Self-Injury, Fall, Loss of Consciousness, Abnormal Dreams, Mood Altered, Completed Suicide, Pulmonary Oedema, Brain Oedema, Depression, Adrenal Haemorrhage, Pupil Fixed, Hallucination, Nervousness, Oxygen Saturation Decreased, Mydriasis, Partner Stress, Amnesia, Anxiety, Emotional Distress, Visceral Congestion, Pneumoconiosis, Hypotonia, Heart Rate Increased, Bradycardia, GUN Shot Wound, Blood Pressure Decreased, Face Injury

Adverse event resulted in: death

Suspect drug(s):
Lorcet Plus Tablets 7.5/650 (Hydrocodone Bitartrate and Acetaminophen)
    Indication: Pain

Talwin NX
    Indication: Pain

Norco
    Indication: Pain

Vicodin
    Indication: Pain

Lortab
    Indication: Pain

Ambien
    Indication: Pain

Temazepam
    Indication: Pain

Dalmane
    Indication: Pain

Restoril
    Indication: Pain

Lidoderm
    Indication: Pain

Lidopain (Lidocaine)
    Indication: Pain

Other drugs received by patient: Zonegran; Proponapat (Nos)

Possible Vicodin side effects / adverse reactions in 20 year old female

Reported by a consumer/non-health professional from United States on 2007-01-27

Patient: 20 year old female

Reactions: Malaise

Adverse event resulted in: death

Suspect drug(s):
Vicodin
    Indication: Pain

Diphenhydramine Hydrochloride
    Administration route: Oral
    Indication: Insomnia
    Start date: 2006-12-09
    End date: 2006-12-09

Antibiotics
    Indication: Drug USE FOR Unknown Indication