VIAGRA SUMMARY
VIAGRA®, an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).
VIAGRA is indicated for the treatment of erectile dysfunction.
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NEWS HIGHLIGHTSMedia Articles Related to Viagra (Sildenafil)
Viagra Won't Help, and May Harm, Patients With a Heart Valve Disorder Source: MedicineNet Pulmonary Hypertension Specialty [2017.08.30] Title: Viagra Won't Help, and May Harm, Patients With a Heart Valve Disorder Category: Health News Created: 8/29/2017 12:00:00 AM Last Editorial Review: 8/30/2017 12:00:00 AM
Viagra-Like Ingredient in Recalled Coffee Source: MedicineNet Product Recalls Home Page Specialty [2017.07.21] Title: Viagra-Like Ingredient in Recalled Coffee Category: Health News Created: 7/20/2017 12:00:00 AM Last Editorial Review: 7/21/2017 12:00:00 AM
Viagra Might Make for a Safer, More Effective Stent Source: MedicineNet Coronary Angioplasty Specialty [2017.07.11] Title: Viagra Might Make for a Safer, More Effective Stent Category: Health News Created: 7/10/2017 12:00:00 AM Last Editorial Review: 7/11/2017 12:00:00 AM
Published Studies Related to Viagra (Sildenafil)
Treatment of palmar-plantar erythrodysesthesia (PPE) with topical sildenafil: a
pilot study. [2015] treatment of PPE... CONCLUSIONS: In this limited, single-center study, topical cream containing 1Â %
Efficacy of daily low-dose sildenafil for treating interstitial cystitis: results
of a randomized, double-blind, placebo-controlled trial--treatment of
interstitial cystitis/painful bladder syndrome with low-dose sildenafil. [2014] treatment of nonulcer interstitial cystitis (IC) in women... CONCLUSION: Daily low-dose sildenafil is an easy, well-tolerated, and effective
Randomized controlled trial of sildenafil for preventing recurrent ischemic
priapism in sickle cell disease. [2014] recurrent ischemic priapism associated with sickle cell disease... CONCLUSIONS: Sildenafil use by systematic dosing may offer a strategy to prevent
Effect of sildenafil on skeletal and cardiac muscle in Becker muscular dystrophy. [2014] heart function in patients with BMD... INTERPRETATION: Despite positive evidence from animal models of dystrophinopathy
Sildenafil citrate in the treatment of pain in primary dysmenorrhea: a randomized
controlled trial. [2013] STUDY QUESTION: Is a vaginal preparation of sildenafil citrate capable of
alleviating acute menstrual pain in patients with primary dysmenorrhea (PD)?
SUMMARY ANSWER: A vaginal preparation of sildenafil citrate is capable of
alleviating acute menstrual pain in patients with PD with no observed adverse
effects.
Clinical Trials Related to Viagra (Sildenafil)
Does Oral Sildenafil (Viagra) Decrease Mean Pulmonary Artery Pressure After Cardiac Surgery? [Completed]
Post-operative pulmonary hypertension is a risk factor for right ventricular failure and an
increasing cause of morbidity and mortality in patients undergoing high-risk cardiac
surgery. Several treatments have been used to treat and reduce post operative pulmonary
hypertension. Unfortunately none of these treatments are approved for use in this condition
and only one (inhaled nitric oxide) is specific enough to pulmonary hypertension to not
cause dangerous low blood pressure in the rest of the body. Sadly, inhaled nitric oxide is
difficult and expensive to use, and can cause lung damage. Sildenafil citrate is quite
specific to the lung vessels, is easy to administer and does not easily cause low blood
pressure in other areas of the body. We hypothesize that oral sildenafil 12. 5mg will
decrease the baseline (pre-dose) mPAP by at least 20% compared with a placebo.
Effects of Viagra on Heart Function in Patients With Heart Failure [Completed]
Sildenafil (Viagra) is known to reduce pulmonary hypertension. Heart failure patients also
have pulmonary hypertension and several recent reports have shown that sildenafil leads to
an improvement in their exercise capacity. In these studies sildenafil caused a reduction
in the pulmonary and systemic vascular resistances, improved pulmonary gas diffusion and
perhaps increased cardiac output. It is uncertain if left ventricular filling pressures are
reduced and whether there is improvement in left ventricular relaxation. The investigators
hypothesize that in heart failure patients the improvement in exercise capacity associated
with sildenafil is related to a significant reduction in left ventricular filling pressures.
The investigators propose to study 20 patients with stable but moderately symptomatic heart
failure. The study design is a randomized cross-over trial of the administration of a
single dose of sildenafil 50 mg or a matching placebo. Exercise capacity will be determined
before and after the oral administration of sildenafil 50 mg or placebo. Left ventricular
filling pressures will be assessed by Doppler echocardiography and the serum level of B-type
natriuretic peptide (BNP is known to increase with higher left ventricular filling
pressures). After an initial echocardiogram and performing a 6 minute walk test, the patient
will then be given either sildenafil or a matching placebo in a randomized double-blind
fashion. One hr later a blood sample for serum BNP, the echocardiogram and the 6 minute
walk test will be repeated.
Sildenafil for Prevention of Cerebral Vasospasm [Withdrawn]
A Randomized Clinical Trial with security and dose testing of Sildenafil Citrate in patients
with subarachnoid hemorrhage due to a rupture of a cerebral aneurism for prevention of
cerebral vasospasm. The cerebral vasospasm is a decrease in blood flow that occurs when the
intracranial vessels lose their capability of self-control of dilations and contractions.
Patients with subarachnoid hemorrhage without neurological deficits who underwent
endovascular or surgical correction of the aneurysm can participate in this trial. They will
be randomized to a daily doses of 75 mg of Sildenafil, 150 mg of Sildenafil or Placebo from
the third to the 14th day post bleeding. Today there is no proven clinical treatment for
prevention of cerebral vasospasm.
Pharmacokinetics of Sildenafil in Premature Infants [Recruiting]
Bioequivalence Study For Orally-Disintegrating Tablet Of Sildenafil [Completed]
The purpose of this study is to assess the bioequivalence of Sildenafil ODT 50 mg without
water to Japanese commercial oral tablet of sildenafil citrate (Viagra® tablet) 50 mg under
fasted conditions.
Reports of Suspected Viagra (Sildenafil) Side Effects
Drug Ineffective (734),
Erection Increased (165),
Headache (117),
Erectile Dysfunction (96),
Penis Disorder (85),
Drug Effect Decreased (63),
Drug Interaction (55),
Incorrect Dose Administered (48),
Penile Pain (47),
Nausea (43), more >>
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PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 4 ratings/reviews, Viagra has an overall score of 6.25. The effectiveness score is 8 and the side effect score is 5.50. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
| Viagra review by 70 year old male patient | | Rating |
Overall rating: | | |
Effectiveness: | | Highly Effective |
Side effects: | | Mild Side Effects | | Treatment Info |
Condition / reason: | | ED |
Dosage & duration: | | 100mg taken 3 x month for the period of 1 year |
Other conditions: | | None |
Other drugs taken: | | None | | Reported Results |
Benefits: | | Strong erections |
Side effects: | | Headache/ mild |
Comments: | | Strong erections |
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| Viagra review by 29 year old male patient | | Rating |
Overall rating: | | |
Effectiveness: | | Highly Effective |
Side effects: | | Extremely Severe Side Effects | | Treatment Info |
Condition / reason: | | Erectile Dysfunction |
Dosage & duration: | | 100mg taken 1 for the period of 1 |
Other conditions: | | High Blood Pressure |
Other drugs taken: | | Enalapril Maleate (not at the same time though) | | Reported Results |
Benefits: | | Very effective. |
Side effects: | | VIAGRA WORKED BUT WITH HORRIBLE SIDE EFFECTS! I only took it once. Around 1040PM, I took a VERY small minute amount of a 100 mg dose. Seven minutes later, the side effects kicked in. I had VERY FAST RAPID HEARTBEAT FOR AN HOUR AND A HALF! I'm 29, with "slightly" high blood pressure (140/90), and I had to call 911 (around 12:00AM) because I SERIOUSLY THOUGHT I WAS GOING TO HAVE A HEART ATTACK! Around 1215AM, the EMS checked my blood pressure and it was at 188 (systolic). I also had facial flushing where my face seemed warmer/hotter than usual. Also, it was so uncomfortable that I had to "walk slower" around my apt and I could barely talk as I had to breathe in more carefully so that I could calm my heart down as much as I could. I didn't go to bed until 4/5am because I was so worried that I might have a heart attack! VIAGRA IS REALLY STRONG AND IT'S NOT SOMETHING TO TAKE LIGHTLY! TAKE A VERY VERY SMALL DOSE IF IT'S YOUR FIRST TIME TAKING IT! I'LL NEVER TAKE IT AGAIN! |
Comments: | | N/A |
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| Viagra review by 29 year old male patient | | Rating |
Overall rating: | | |
Effectiveness: | | Highly Effective |
Side effects: | | Extremely Severe Side Effects | | Treatment Info |
Condition / reason: | | Erectile Dysfunction |
Dosage & duration: | | 100mg taken 1 for the period of 1 |
Other conditions: | | High Blood Pressure |
Other drugs taken: | | Enalapril Maleate (not at the same time though) | | Reported Results |
Benefits: | | Very effective. |
Side effects: | | VIAGRA WORKED BUT WITH HORRIBLE SIDE EFFECTS! I only took it once. Around 1040PM, I took a VERY small minute amount of a 100 mg dose. Seven minutes later, the side effects kicked in. I had VERY FAST RAPID HEARTBEAT FOR AN HOUR AND A HALF! I'm 29, with "slightly" high blood pressure (140/90), and I had to call 911 (around 12:00AM) because I SERIOUSLY THOUGHT I WAS GOING TO HAVE A HEART ATTACK! Around 1215AM, the EMS checked my blood pressure and it was at 188 (systolic). I also had facial flushing where my face seemed warmer/hotter than usual. Also, it was so uncomfortable that I had to "walk slower" around my apt and I could barely talk as I had to breathe in more carefully so that I could calm my heart down as much as I could. I didn't go to bed until 4/5am because I was so worried that I might have a heart attack! VIAGRA IS REALLY STRONG AND IT'S NOT SOMETHING TO TAKE LIGHTLY! TAKE A VERY VERY SMALL DOSE IF IT'S YOUR FIRST TIME TAKING IT! I'LL NEVER TAKE IT AGAIN! |
Comments: | | N/A |
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Page last updated: 2017-08-30
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