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Viagra (Sildenafil Citrate) - Summary

 
 



VIAGRA SUMMARY

VIAGRA®
(sildenafil citrate)
Tablets

VIAGRA® , an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).

VIAGRA is indicated for the treatment of erectile dysfunction.


See all Viagra indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Viagra (Sildenafil)

Around two thirds of Viagra consumed in the Netherlands may be illegal, warn Dutch experts
Source: Erectile Dysfunction / Premature Ejaculation News From Medical News Today [2014.07.03]
At least two-thirds of the erectile dysfunction drug sildenafil (e.g. Viagra) consumed in the Netherlands may be illegal, warn researchers today.In a letter published on bmj.

Chemists develop new approach to detect counterfeit Viagra and other medicines on the Internet
Source: Erectile Dysfunction / Premature Ejaculation News From Medical News Today [2014.05.22]
Researchers at the University of Montreal have developed an improved chemical analysis method that is more efficient and faster in detecting counterfeit medicines, which have skyrocketed in recent...

Possibility of Viagra as heart failure drug 'complicated by estrogen interaction'
Source: Erectile Dysfunction / Premature Ejaculation News From Medical News Today [2014.05.18]
Currently under consideration as a heart failure treatment, new research shows that the erectile dysfunction drug Viagra may work very differently in women than in men.

Menstrual cramping may be alleviated by vaginally administered sildenafil citrate
Source: Erectile Dysfunction / Premature Ejaculation News From Medical News Today [2013.12.09]
Women with moderate to severe menstrual cramps may find relief in a class of erectile dysfunction drugs, according to a team of researchers led by Penn State College of Medicines Richard Legro.

Sildenafil Helps Turn 'Bad' White Adipose Tissue Into 'Good And Healthy' Brown Adipose Tissue
Source: Erectile Dysfunction / Premature Ejaculation News From Medical News Today [2013.04.03]
Although sildenafil is best known for promoting erections, it may also serve as a weight loss aid by coaxing our bodies to store more healthy "brown fat" relative to unhealthy "white fat" than it...

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Published Studies Related to Viagra (Sildenafil)

The effect of sildenafil on respiratory weaning of patients with chronic obstructive pulmonary diseases admitted to intensive care unit. [2012]
facilitating the weaning of COPD patients from the ventilator... CONCLUSION: Sildenafil facilitated weaning of COPD patients from the ventilator

Sildenafil for chronic obstructive pulmonary disease: a randomized crossover trial. [2012]
exercise capacity in patients with COPD and emphysema... CONCLUSIONS: Routine sildenafil administration did not have a beneficial effect

A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study of Oral Sildenafil Citrate in Treatment-Naive Children with Pulmonary Arterial Hypertension. [2011.11.29]
CONCLUSIONS: Sixteen-week sildenafil monotherapy is well tolerated in pediatric PAH. Percentage change in pVO(2) for the three sildenafil doses combined was only marginally significant; however, pVO(2), FC, and hemodynamic improvements with medium and high doses suggest efficacy with these doses. Combined with STARTS-2 data, the overall profile favors the medium dose. Further investigation is warranted to determine optimal dosing based on age and weight. CLINICAL TRIAL REGISTRATION: http://clinicaltrials.gov; NCT00159874.

Phosphodiesterase 5 inhibition with sildenafil reverses exercise oscillatory breathing in chronic heart failure: a long-term cardiopulmonary exercise testing placebo-controlled study. [2011.11.07]
CONCLUSIONS: PDE5 inhibition in HF patients with EOB offers the dual advantage of improving functional capacity and modulating the EOB pattern. PAP and PVR reduction seem to underlie the correction of the breathing disorder. Whether reversal of this unfavourable prognostic signal can affect survival remains unconfirmed at the moment.

Long-term Treatment With Sildenafil Citrate in Pulmonary Arterial Hypertension: The SUPER-2 Study. [2011.11]
BACKGROUND: The long-term safety and tolerability of sildenafil treatment of pulmonary arterial hypertension (PAH) were assessed... CONCLUSIONS: Long-term treatment of PAH initiated as sildenafil monotherapy was generally well tolerated. After 3 years, the majority of patients (60%) who entered the SUPER-1 trial improved or maintained their functional status, and 46% maintained or improved 6MWD. Trial registry: ClinicalTrials.gov; No.: NCT00159887; URL: www.clinicaltrials.gov.

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Clinical Trials Related to Viagra (Sildenafil)

A Multicenter, Double-Blind Study to Evaluate the Effect of Pretreatment With a Daily Dose of Sildenafil on the As-Needed Efficacy of Viagra in Men With Erectile Dysfunction and Type 2 Diabetes [Completed]
To determine the effect on erectile function in a population of type 2 diabetic men with erectile dysfunction who have undergone the following treatment regimen: pre-treatment with a daily dose of double-blind sildenafil versus placebo for 4 weeks (Phase I) followed by an as-needed, flexible-dose, open-label treatment phase with sildenafil for 12 weeks (Phase II). To assess safety and tolerability of this dosing regimen and to investigate its effects on endothelial function and subject's responses to the Self-Esteem And Relationship (SEAR) questionnaire.

A Placebo-Controlled Single-Dose Trial of Sildenafil in Schizophrenia [Completed]
The study is a double-blind, placebo-controlled, random-order, single-dose crossover trial of sildenafil 50 & 100 mg added to stable antipsychotic treatment in schizophrenia patients to assess whether this PDE5 inhibitor improves cognitive functioning (including verbal memory, fluency, attention, spatial memory, motor speed, and executive function) and clinical symptoms (psychotic, negative, mood symptoms, and self-reports of side-effects).

Sildenafil (Viagra) Treatment of Subacute Ischemic Stroke [Recruiting]
Stroke is the third leading cause of death in the United States and the leading cause of serious long-term disability. Approximately 50% of the 750,000 people affected by stroke each year have residual physical impairment. Treatment options for recovery are limited at this time. Sildenafil (Viagra) has demonstrated the capability of significantly improving recovery in several animal experiments of stroke. This study is aiming to establish the safety of treatment with sildenafil in people with stroke with the ultimate aim of testing its usefulness to improve recovery.

Impact Of Viagra On Sexual Satisfaction Of Men With Mild Erectile Dysfunction Who Are Sexually Dissatisfied [Completed]
Men's quality of life (QoL) is potentially affected by mild erectile dysfunction (ED) to the same extent as it is by moderate and severe ED. This study will provide controlled clinical data measuring efficacy, QoL parameters and satisfaction changes in men with mild ED treated with Viagra versus those treated with a placebo. With an open-label extension, this study will also provide all study subjects the opportunity to receive the active drug treatment for 6 weeks.

Sildenafil Citrate in Waldenstrom's Macroglobulinemia [Terminated]
The purpose of this study is to determine the effects (good or bad) that sildenafil (Viagra) has on patients with slow growing Waldenstrom's macroglobulinemia (WM). Sildenafil blocks the function of several proteins necessary to the survival of certain types of cancer and laboratory tests have shown that it can destroy WM cells.

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Reports of Suspected Viagra (Sildenafil) Side Effects

Drug Ineffective (734)Erection Increased (165)Headache (117)Erectile Dysfunction (96)Penis Disorder (85)Drug Effect Decreased (63)Drug Interaction (55)Incorrect Dose Administered (48)Penile Pain (47)Nausea (43)more >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 4 ratings/reviews, Viagra has an overall score of 6.25. The effectiveness score is 8 and the side effect score is 5.50. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
 

Viagra review by 70 year old male patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   ED
Dosage & duration:   100mg taken 3 x month for the period of 1 year
Other conditions:   None
Other drugs taken:   None
  
Reported Results
Benefits:   Strong erections
Side effects:   Headache/ mild
Comments:   Strong erections

 

Viagra review by 29 year old male patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Extremely Severe Side Effects
  
Treatment Info
Condition / reason:   Erectile Dysfunction
Dosage & duration:   100mg taken 1 for the period of 1
Other conditions:   High Blood Pressure
Other drugs taken:   Enalapril Maleate (not at the same time though)
  
Reported Results
Benefits:   Very effective.
Side effects:   VIAGRA WORKED BUT WITH HORRIBLE SIDE EFFECTS! I only took it once. Around 1040PM, I took a VERY small minute amount of a 100 mg dose. Seven minutes later, the side effects kicked in. I had VERY FAST RAPID HEARTBEAT FOR AN HOUR AND A HALF! I'm 29, with "slightly" high blood pressure (140/90), and I had to call 911 (around 12:00AM) because I SERIOUSLY THOUGHT I WAS GOING TO HAVE A HEART ATTACK! Around 1215AM, the EMS checked my blood pressure and it was at 188 (systolic). I also had facial flushing where my face seemed warmer/hotter than usual. Also, it was so uncomfortable that I had to "walk slower" around my apt and I could barely talk as I had to breathe in more carefully so that I could calm my heart down as much as I could. I didn't go to bed until 4/5am because I was so worried that I might have a heart attack! VIAGRA IS REALLY STRONG AND IT'S NOT SOMETHING TO TAKE LIGHTLY! TAKE A VERY VERY SMALL DOSE IF IT'S YOUR FIRST TIME TAKING IT! I'LL NEVER TAKE IT AGAIN!
Comments:   N/A

 

Viagra review by 29 year old male patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Extremely Severe Side Effects
  
Treatment Info
Condition / reason:   Erectile Dysfunction
Dosage & duration:   100mg taken 1 for the period of 1
Other conditions:   High Blood Pressure
Other drugs taken:   Enalapril Maleate (not at the same time though)
  
Reported Results
Benefits:   Very effective.
Side effects:   VIAGRA WORKED BUT WITH HORRIBLE SIDE EFFECTS! I only took it once. Around 1040PM, I took a VERY small minute amount of a 100 mg dose. Seven minutes later, the side effects kicked in. I had VERY FAST RAPID HEARTBEAT FOR AN HOUR AND A HALF! I'm 29, with "slightly" high blood pressure (140/90), and I had to call 911 (around 12:00AM) because I SERIOUSLY THOUGHT I WAS GOING TO HAVE A HEART ATTACK! Around 1215AM, the EMS checked my blood pressure and it was at 188 (systolic). I also had facial flushing where my face seemed warmer/hotter than usual. Also, it was so uncomfortable that I had to "walk slower" around my apt and I could barely talk as I had to breathe in more carefully so that I could calm my heart down as much as I could. I didn't go to bed until 4/5am because I was so worried that I might have a heart attack! VIAGRA IS REALLY STRONG AND IT'S NOT SOMETHING TO TAKE LIGHTLY! TAKE A VERY VERY SMALL DOSE IF IT'S YOUR FIRST TIME TAKING IT! I'LL NEVER TAKE IT AGAIN!
Comments:   N/A

See all Viagra reviews / ratings >>

Page last updated: 2014-07-03

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