Vesicare (Solifenacin Succinate) - Summary

VESICARE SUMMARY

VESIcare^®  (solifenacin succinate) is a muscarinic receptor antagonist.

VESIcare is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.

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VESICARE NEWS HIGHLIGHTS

Published Studies Related to Vesicare (Solifenacin)

Randomized, double-blind, placebo- and propiverine-controlled trial of the once-daily antimuscarinic agent solifenacin in Japanese patients with overactive bladder. [2007.09]

Nocturnal polyuria and nocturia relief in patients treated with solifenacin for overactive bladder symptoms. [2007.07]

Reductions in overactive bladder-related incontinence from pooled analysis of phase III trials evaluating treatment with solifenacin. [2006.09]

Multiple doses of the antimuscarinic agent solifenacin do not affect the pharmacodynamics or pharmacokinetics of warfarin or the steady-state pharmacokinetics of digoxin in healthy subjects. [2006.08]

Short- and long-term efficacy of solifenacin treatment in patients with symptoms of mixed urinary incontinence. [2006.06]

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Clinical Trials Related to Vesicare (Solifenacin)

Open-Label Study of the Efficacy and Safety of VESIcare® in Patients With Overactive Bladder Symptoms [Completed]

Efficacy & Safety Study of VESIcare® (Solifenacin Succinate) in Patients Wishing to Switch From Detrol LA® for Treatment of Overactive Bladder [Completed]

A Study of Solifenacin With Bladder Training Versus Solifenacin Alone in Patients With Overactive Bladder (SOLAR) [Active, not recruiting]

A Multicenter VESIcare® Efficacy and Safety Study for the Treatment of Urgency Associated With Overactive Bladder (OAB) [Completed]

Study to Compare the Safety and Efficacy of Solifenacin With Oxybutynin for the Treatment of Overactive Bladder (VECTOR) [Active, not recruiting]

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VESICARE PATIENT REVIEWS / RATINGS / COMMENTS

Vesicare review by 42 year old female patient
		Rating
Overall rating:
Effectiveness:		Considerably Effective
Side effects:		Mild Side Effects
		Treatment Info
Condition / reason:		frequent urination
Dosage & duration:		10mg taken 1/day for the period of continue
Other conditions:		lack of sleep
Other drugs taken:		n/a
		Reported Results
Benefits:		I was able to hold and wait to use restroom and urges were less frequent.
Side effects:		dry mouth constipation
Comments:		I've been taking 5 mg per day for a month and I felt it was losing effectiveness so incresed to 10 mg and been taking 3 month so far. I still have some what of problem before period and have more frequent urge to goto restroom than other people but I am able to hole and wait. It is much more controlable than I wasn't taking anything.

Vesicare review by 53 year old female patient
		Rating
Overall rating:
Effectiveness:		Highly Effective
Side effects:		No Side Effects
		Treatment Info
Condition / reason:		urge incontinence and bladder spasm
Dosage & duration:		5mg taken once daily for the period of continuously
Other conditions:		asthma
Other drugs taken:		salbutamol occasionally
		Reported Results
Benefits:		Bladder spasms and urge incontinence were banished immediately. Urinary frequency continued but is becoming less as I am able to retrain my bladder to hold more urine. I was particularly pleased not to suffer from constipation or dry mouth which are listed as common side effects.
Side effects:		None
Comments:		Vesicare 5mg tablet taken once daily in the morning.

Vesicare review by 53 year old female patient
		Rating
Overall rating:
Effectiveness:		Highly Effective
Side effects:		No Side Effects
		Treatment Info
Condition / reason:		urge incontinence and bladder spasm
Dosage & duration:		5mg taken once daily for the period of continuously
Other conditions:		asthma
Other drugs taken:		salbutamol occasionally
		Reported Results
Benefits:		Bladder spasms and urge incontinence were banished immediately. Urinary frequency continued but is becoming less as I am able to retrain my bladder to hold more urine. I was particularly pleased not to suffer from constipation or dry mouth which are listed as common side effects.
Side effects:		None
Comments:		Vesicare 5mg tablet taken once daily in the morning.