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Vasocidin (Prednisolone Sodium Phosphate / Sulfacetamide Sodium Ophthalmic) - Summary




VASOCIDIN is a sterile topical ophthalmic solution combining an anti-infective and an adrenocortical steroid having the following composition:

Sulfacetamide Sodium 100 mg/mL

(bacteriostatic antibacterial)

Prednisolone Sodium Phosphate 2.5mg/mL

(equivalent to Prednisolone Phosphate 2.3 mg/mL)

(adrenocortical steroid/anti-inflammatory)

VASOCIDIN is indicated for corticosteroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists.

Ocular corticosteroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe where the inherent risk of corticosteroid use in certain infective conjunctivitides is accepted to obtain diminution in edema and inflammation. They are also indicated in chronic anterior uveitis and corneal injury from chemical, radiation, or thermal burns or penetration of foreign bodies.

The use of a combination drug with an anti-infective component is indicated where the risk of superficial ocular infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye.

The particular anti-infective drug in this product is active against the following common bacterial eye pathogens: Escherichia coli, Staphylococcus aureus , Streptococcus pneumoniae , Streptococcus ( viridans group), Haemophilus influenzae , Klebsiella species, and Enterobacter species.

This product does not provide adequate coverage against: Neisseria species, Serratia marcescens .

A significant percentage of staphylococcal isolates are completely resistant to sulfa drugs.

See all Vasocidin indications & dosage >>


Published Studies Related to Vasocidin (Prednisolone / Sulfacetamide Ophthalmic)

An ocular bioavailability comparison in rabbits of prednisolone acetate after repeated topical applications formulated as a high-viscosity gel and as an aqueous suspension. [1996.06]
To increase contact time between drug and ocular surface and thus improve the ocular bioavailability, we used the high-viscous, water-soluble polymer carbomer Leogel (carbomer 0.5%). We compared the bioavailability of prednisolone acetate 0.5% given in 1) Leogel using fusidic acid 1% with that obtained using 2) aqueous sulfacetamide sodium 10% as vehicle...

more studies >>

Clinical Trials Related to Vasocidin (Prednisolone / Sulfacetamide Ophthalmic)

SuPr Study (Supine Versus Prone Treatment Position in Breast Radiotherapy) [Recruiting]
A randomised, two-arm, non-blinded crossover study investigating the impact of treatment position (prone versus supine) upon reproducibility of tumour bed position in patients undergoing breast radiotherapy following excision of early breast cancer.

Intraductal Meibomian Gland Probing Trial [Active, not recruiting]
In this research study, the investigators are looking at the effects of Meibomian Gland Probing (MGP) versus a sham (fake) procedure in patients with refractory MGD who have already tried traditional management with no success in resolving their clinical signs (as seen by their ophthalmologist) or their symptoms. The investigators are also evaluating the effects of using two (2) post-procedural medication treatments: Blephamide or GenTeal PM Night-Time to determine if treatment after the MGP procedure has an effect on its outcome.

Evaluation of a Diet in Patients With Senile Dementia [Recruiting]

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Page last updated: 2006-01-31

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