VASOCIDIN is a sterile topical ophthalmic solution combining an anti-infective and an adrenocortical steroid having the following composition:
Sulfacetamide Sodium 100 mg/mL
Prednisolone Sodium Phosphate 2.5mg/mL
(equivalent to Prednisolone Phosphate 2.3 mg/mL)
VASOCIDIN is indicated for corticosteroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists.
Ocular corticosteroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe where the inherent risk of corticosteroid use in certain infective conjunctivitides is accepted to obtain diminution in edema and inflammation. They are also indicated in chronic anterior uveitis and corneal injury from chemical, radiation, or thermal burns or penetration of foreign bodies.
The use of a combination drug with an anti-infective component is indicated where the risk of superficial ocular infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye.
The particular anti-infective drug in this product is active against the following common bacterial eye pathogens: Escherichia coli, Staphylococcus aureus , Streptococcus pneumoniae , Streptococcus ( viridans group), Haemophilus influenzae , Klebsiella species, and Enterobacter species.
This product does not provide adequate coverage against: Neisseria species, Serratia marcescens .
A significant percentage of staphylococcal isolates are completely resistant to sulfa drugs.