Valium (Diazepam) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

Side effects most commonly reported were drowsiness, fatigue, muscle weakness, and ataxia. The following have also been reported:

Central Nervous System:

confusion, depression, dysarthria, headache, slurred speech, tremor, vertigo

Gastrointestinal System:

constipation, nausea, gastrointestinal disturbances

Special Senses:

blurred vision, diplopia, dizziness

Cardiovascular System:

hypotension

Psychiatric and Paradoxical Reactions:

stimulation, restlessness, acute hyperexcited states, anxiety, agitation, aggressiveness, irritability, rage, hallucinations, psychoses, delusions, increased muscle spasticity, insomnia, sleep disturbances, and nightmares. Inappropriate behavior and other adverse behavioral effects have been reported when using benzodiazepines. Should these occur, use of the drug should be discontinued. They are more likely to occur in children and in the elderly.

Urogenital System:

incontinence, changes in libido, urinary retention

Skin and Appendages:

skin reactions

Laboratories:

elevated transaminases and alkaline phosphatase

Other:

changes in salivation, including dry mouth, hypersalivation

Antegrade amnesia may occur using therapeutic dosages, the risk increasing at higher dosages. Amnestic effects may be associated with inappropriate behavior.

Minor changes in EEG patterns, usually low-voltage fast activity, have been observed in patients during and after Valium therapy and are of no known significance.

Because of isolated reports of neutropenia and jaundice, periodic blood counts and liver function tests are advisable during long-term therapy.

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO VALIUM

Possible Valium side effects / adverse reactions in 15 year old male

Reported by a lawyer from United States on 2007-01-10

Patient: 15 year old male weighing 54.4 kg (119.7 pounds)

Reactions: Gastrointestinal Haemorrhage, Rectal Haemorrhage, Rheumatic Fever, Intentional Drug Misuse, Gastritis, Substance Abuse, Suicidal Ideation, Rheumatoid Arthritis, Ureteric Obstruction, Musculoskeletal Disorder, Ileitis, Injury, Depression, Tendonitis, Vomiting, Polyp, Nausea, Suicidal Behaviour, Anaemia, Crohn's Disease, Neck Injury, Intestinal Obstruction, Tendon Calcification, Ligament Calcification, Autoimmune Disorder, Panic Attack, Gastrointestinal Disorder, Suicide Attempt, Homicidal Ideation, Multi-Organ Disorder, Inflammatory Bowel Disease

Adverse event resulted in: hospitalization, disablity

Suspect drug(s):
Accutane
    Indication: Acne
    Start date: 1996-10-03
    End date: 1996-11-15

Accutane
    Start date: 1996-11-15
    End date: 1997-08-18

Valium
    Indication: Drug USE FOR Unknown Indication
    Start date: 2004-10-03
    End date: 2004-10-03

Possible Valium side effects / adverse reactions in 32 year old female

Reported by a physician from France on 2007-01-19

Patient: 32 year old female

Reactions: Overdose, Suicide Attempt

Adverse event resulted in: hospitalization

Suspect drug(s):
Valium
    Administration route: Oral
    Indication: Anxiety

Mepronizine
    Administration route: Oral
    Indication: Sleep Disorder

Possible Valium side effects / adverse reactions in 52 year old female

Reported by a individual with unspecified qualification from United States on 2007-01-26

Patient: 52 year old female weighing 56.7 kg (124.7 pounds)

Reactions: Drug Toxicity, Completed Suicide

Adverse event resulted in: death

Suspect drug(s):
Fentanyl Transdermal System
    Dosage: transdermal
    Indication: Ovarian Cancer
    End date: 2006-11-14

Valium
    Dosage: oral
    Administration route: Oral

Acetaminophen
    Dosage: oral
    Administration route: Oral