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Urea Nail Stick (Urea Topical) - Summary

 
 



SUMMARY

River's Edge 50% Urea Nail Stick is a keratolytic solution, which is
a gentle, yet potent, tissue softener for nails. Each mL of River's Edge 50% Urea
Nail Stick contains 50% Urea, Disodium EDTA, Hydroxyethylcellulose, Lactic Acid,
Propylene Glycol, Purified Water, Triethanolamine, Xanthan Gum and Zinc Pyrithione.

50% Urea Nail Stick (Urea) is indicated for the following:

For debridement and promotion of normal healing of
hyperkeratotic surface lesions, particularly where healing is retarded by local
infection, necrotic tissue, fibrinous or purulent debris or eschar. Urea is useful for
the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis,
psoriasis, xerosis, ichthyosis, eczema, keratosis, keratoderma, corns and calluses,
as well as damaged, devitalized, and ingrown nails.


See all Urea Nail Stick indications & dosage >>

NEWS HIGHLIGHTS

Published Studies Related to Urea Nail Stick (Urea Topical)

Efficacy of topical 10% urea-based lotion in patients with ichthyosis vulgaris: a two-center, randomized, controlled, single-blind, right-vs.-left study in comparison with standard glycerol-based emollient cream. [2011.12]
Abstract Background: Ichthyoses are genetic disorders of keratinization which are uncomfortable due to their conspicuous scaling, itching and cosmetic problems.Further studies with larger sample sizes are needed for the evaluation of safety and tolerability of urea 10% lotion in this clinical setting.

Clinical evaluation of 35% urea in a water-lipid-based foam containing lactic acid for treatment of mild-to-moderate xerosis of the foot. [2011.03]
BACKGROUND: We evaluated 35% urea in a water-lipid-based foam delivery system containing lactic acid in participants with mild-to-moderate xerosis of the foot... CONCLUSIONS: Thirty-five percent urea in a water-lipid-based foam delivery system containing lactic acid can be an appropriate treatment option for mild-to-moderate xerosis of the foot.

Placebo-controlled trial to determine the effectiveness of a urea/lactic acid-based topical keratolytic agent for prevention of capecitabine-induced hand-foot syndrome: North Central Cancer Treatment Group Study N05C5. [2010.12.10]
PURPOSE: Hand-foot syndrome (HFS) is a dose-limiting toxicity of capecitabine for which no effective preventative treatment has been definitively demonstrated. This trial was conducted on the basis of preliminary data that a urea/lactic acid-based topical keratolytic agent (ULABTKA) may prevent HFS... CONCLUSION: These data do not support the efficacy of a ULABTKA cream for preventing HFS symptoms in patients receiving capecitabine.

Placebo-controlled trial to determine the effectiveness of a urea/lactic acid-based topical keratolytic agent for prevention of capecitabine-induced hand-foot syndrome: North Central Cancer Treatment Group Study N05C5. [2010]
acid-based topical keratolytic agent (ULABTKA) may prevent HFS... CONCLUSION: These data do not support the efficacy of a ULABTKA cream for

A randomized, double-blind, placebo-controlled study to evaluate the efficacy in AD of liquid soap containing 12% ammonium lactate + 20% urea. [2009.12]
Atopic dermatitis (AD) is a common chronic skin disease, which mainly affects children... The liquid soap was found to be effective in patients with AD, as use of this soap in patients with stable mild to moderate AD improved the parameters studied.

more studies >>

Clinical Trials Related to Urea Nail Stick (Urea Topical)

Study in Healthy Subjects, Patients With Urea Cycle Disorders (UCD) and Carriers of UCD Mutations to Evaluate Urea Cycle Function [Recruiting]
This diagnostic study will be performed to investigate the performance of the urea cycle in healthy subjects, asymptomatic carriers of Urea Cycle Disorders (UCD) mutations and subjects with genetically proven urea cycle disorders. The ureagenesis rate will be measured by 13C incorporation assay, a method for in vivo measurement of urea cycle performance with stable isotopes.

Sorafenib-induced Hand- Foot Skin Reaction Treatment [Recruiting]

Human Heterologous Liver Cells for Infusion in Children With Urea Cycle Disorders [Recruiting]
Treatment with liver cell infusion for children with urea cycle disorders (UCD).

Human Heterologous Liver Cells for Infusion in Children With Urea Cycle Disorders [Recruiting]
Urea cycle disorders are rare inherited diseases that generally have a poor outcome. In this study, neonates and infants with UCD will be included within the first 3 months of life and will be treated by repetitive application of human liver cells to reduce the risk of neurological deterioration while awaiting OLT.

Neurologic Injuries in Adults With Urea Cycle Disorders [Recruiting]
Urea cycle disorders (UCDs) are a group of rare inherited metabolism disorders. The purpose of this study is to evaluate how UCD-related neurologic injuries affect adults with one of the most common types of UCD.

more trials >>


Page last updated: 2013-02-10

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