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Ultrase (Lipase / Amylase / Protease) - Description and Clinical Pharmacology

 
 



DESCRIPTION

ULTRASE® (pancrelipase) Capsules are orally administered capsules containing enteric-coated microspheres of porcine pancreatic enzyme concentrate, predominantly pancreatic lipase, amylase, and protease.

Each ULTRASE  ® capsule contains:

Lipase            4,500 U.S.P. Units

Amylase       20,000 U.S.P. Units

Protease       25,000 U.S.P. Units

Inactive ingredients: povidone, talc, sugar, methacrylic acid copolymer (Type C), triethyl citrate, simethicone emulsion.

CLINICAL PHARMACOLOGY

ULTRASE® (pancrelipase) Capsules are designed to prevent inactivation by gastric acid thereby resulting in the delivery of high levels of biologically active enzymes into the duodenum. The enzymes catalyze the hydrolysis of fats into glycerol and fatty acids, starch into dextrins and sugars, and protein into proteoses and derived substances.

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