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Ultane (Sevoflurane Inhalation) - Summary

 
 



ULTANE SUMMARY

ULTANE (sevoflurane), volatile liquid for inhalation, a nonflammable and nonexplosive liquid administered by vaporization, is a halogenated general inhalation anesthetic drug.

Sevoflurane is indicated for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.

Sevoflurane should be administered only by persons trained in the administration of general anesthesia. Facilities for maintenance of a patent airway, artificial ventilation, oxygen enrichment, and circulatory resuscitation must be immediately available. Since level of anesthesia may be altered rapidly, only vaporizers producing predictable concentrations of sevoflurane should be used.


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NEWS HIGHLIGHTS

Media Articles Related to Ultane (Sevoflurane Inhalation)

Anti-arthritics can exacerbate other inflammatory diseases like periodontitis
Source: Arthritis / Rheumatology News From Medical News Today [2014.07.14]
Inflammatory diseases can occur simultaneously in distinct sites in the same patient, complicating treatment because a medication effective for one disorder may exacerbate the other.

FDA allows marketing of first prosthetic arm that translates signals from person's muscles to perform complex tasks
Source: Rehabilitation / Physical Therapy News From Medical News Today [2014.05.13]
The U.S. Food and Drug Administration (FDA) has allowed marketing of the DEKA Arm System, the first prosthetic arm that can perform multiple, simultaneous powered movements controlled by electrical...

Stimulating a specific brain pathway may induce active emergence from anesthesia
Source: Neurology / Neuroscience News From Medical News Today [2014.07.24]
Researchers may be one step closer to better understanding how anesthesia works.

Study finds low hand hygiene compliance rates during anesthesia administration
Source: Pain / Anesthetics News From Medical News Today [2014.07.02]
Anesthesia providers are missing opportunities to clean their hands during surgical procedures, according to a study published in the American Journal of Infection Control, the official publication...

Use of regional anesthesia during hip fracture surgery not associated with lower risk of death
Source: Pain / Anesthetics News From Medical News Today [2014.06.24]
Among more than 56,000 adults undergoing hip repair between 2004 and 2011, the use of regional anesthesia compared with general anesthesia was not associated with a lower risk of death at 30 days...

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Published Studies Related to Ultane (Sevoflurane Inhalation)

Effect of one minimum alveolar concentration sevoflurane with and without fentanyl on hemodynamic response to laryngoscopy and tracheal intubation. [2011.10]
BACKGROUND: Drug combinations can be used for optimum obtundation of the hemodynamic response to tracheal intubation. The objective of this trial was to compare the hemodynamic response to laryngoscopy and tracheal intubation after administration of 2 mug/kg fentanyl bolus or a placebo with 2% end tidal sevoflurane at induction of anesthesia... CONCLUSION: Addition of 2 mug fentanyl bolus to 1 MAC sevoflurane anesthesia at induction attenuated the hemodynamic response to a maximum of 15% above baseline values.

Prophylactic use of midazolam or propofol at the end of surgery may reduce the incidence of emergence agitation after sevoflurane anaesthesia. [2011.09]
Sevoflurane is associated with a high incidence of emergence agitation in children. Midazolam and propofol have been examined with the aim of reducing emergence agitation after sevoflurane anaesthesia...

Respiratory resistance during anaesthesia with isoflurane, sevoflurane, and desflurane: a randomized clinical trial. [2011.09]
BACKGROUND: To investigate whether the effects of desflurane on inspiratory resistance are similar to those of isoflurane and sevoflurane during 30 min administration at 1 and 1.5 MAC in patients with healthy lungs... CONCLUSIONS: In healthy adults, neither sevoflurane nor isoflurane produced bronchodilation at 1 and 1.5 MAC. Desflurane did not affect respiratory resistance at 1 MAC, but at 1.5 MAC caused significant increase in both total and airway resistance with return to near baseline values after discontinuation of the agent.

Effect of charcoal filter on the emergence from sevoflurane anesthesia in a semi-closed rebreathing circuit. [2011.07]
PURPOSE: A charcoal filter attached within the anesthetic circuit has been shown to efficiently adsorb halothane or isoflurane, thus hastening anesthetic recovery in low or minimal flow system. This study was intended to demonstrate whether the charcoal filter enhances the recovery time from sevoflurane anesthesia using a semi-closed circuit system... CONCLUSION: A charcoal filter enhances the recovery from sevoflurane anesthesia with a semi-closed rebreathing circuit.

Intravenous landiolol, a novel beta(1)-adrenergic blocker, reduces the minimum alveolar concentration of sevoflurane in women. [2011.06]
STUDY OBJECTIVE: To investigate the effect of intravenous (IV) landiolol, a novel beta(1)-adrenergic blocker, on the minimum alveolar concentration (MAC) of sevoflurane in adult women... CONCLUSIONS: IV landiolol reduces the MAC of sevoflurane in women by approximately 20%. Copyright (c) 2011 Elsevier Inc. All rights reserved.

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Clinical Trials Related to Ultane (Sevoflurane Inhalation)

Compare Pharmaco-economics and Efficacy of Sevoflurane With Low Fresh Gas Flow Balanced Anesthesia, Propofol Target Controlled Infusion Anesthesia and Propofol Induction Sevoflurane Maintenance Anesthesia [Not yet recruiting]
This study is performed to demonstrate that the direct anesthetic costs of a low fresh gas flow balanced sevoflurane anesthesia for elective laparoscopy are less compared to the direct anesthetic costs of a target-controlled infusion anesthesia based on propofol.

Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Required General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on Cardiovascular System in Common Clinical Practice [Recruiting]
The main objective of this post-marketing observational study (PMOS) is to collect data of using general anesthesia in patients undergoing any surgery for creating local recommendations. These data will be based on the evaluation of volatile induction and maintenance anesthesia (VIMA) with Sevorane (sevoflurane) in adult patients required general anesthesia for surgery in terms of quality of anesthesia, its influence on cardiovascular system in common clinical practice in Kazakhstan

Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Required General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on Cardiovascular System in Common Clinical Practice [Recruiting]
The main objective of this post-marketing observational study (PMOS) is to collect data of using general anesthesia in patients undergoing any surgery for creating local recommendations. These data will be based on the evaluation of volatile induction and maintenance anesthesia (VIMA) with Sevorane (sevoflurane) in adult patients required general anesthesia for surgery in terms of quality of anesthesia, its influence on cardiovascular system in common clinical practice in Ukraine

Comparing Desflurane to Sevoflurane for the Effect on Recovery Time in Patients Undergoing Urological Cystoscope Surgery [Recruiting]
This is a single-center, prospective, randomized, double-blind, double-arm trial including 68 subjects scheduled to undergo urological cystoscope surgeries under general anesthesia (GA) with intubation through a laryngeal mask airway (LMA) at The Ohio State University Medical Center (OSUMC). Double blinding will be based on both the subject and the research staff being unaware of which trial arm the subject is randomized into. Eligible subjects that provide voluntary and written informed consent will be included in this study.

Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures [Recruiting]
Sevoflurane is an FDA-approved anesthetic drug commonly used for anesthesia during second trimester abortion procedures. It has a few advantages, including ease of use by the anesthesia provider. However, the literature suggests that when used in doses higher than those used at OHSU and Lovejoy, it is associated with an increase in the risk of bleeding. The investigators study aims to test whether the lower dose used at OHSU and Lovejoy during second trimester abortion procedures causes any difference in blood loss, when compared to similar abortion procedures for which this drug is not used.

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Reports of Suspected Ultane (Sevoflurane Inhalation) Side Effects

Aggression (5)Confusional State (4)Amnesia (4)Anaesthetic Complication Neurological (4)Accidental Exposure (3)Body Temperature Increased (1)Hyperthermia Malignant (1)Metabolic Acidosis (1)Delirium (1)Heart Rate Increased (1)


Page last updated: 2014-07-24

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