SUMMARY
TYZINE® NASAL SOLUTION
Tyzine®
Nasal Solution contains tetrahydrozoline hydrochloride, 2-(1,2,3,4-Tetrahydro-1, naphthyl)-2-imidazoline monohydrochloride, as a nasal decongestant.
Tyzine®
Nasal Solution is indicated for decongestion of nasal and nasopharyngeal mucosa.
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NEWS HIGHLIGHTS
Published Studies Related to Tyzine Pediatric (Tetrahydrozoline Nasal)
Serum concentrations in three children with unintentional tetrahydrozoline overdose. [2011.06]
CONCLUSION: We report three pediatric cases after ingestion of THZ where plasma concentrations were obtained with a calculated half-life of 4.4 h in one case.
Prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline. [2008.02]
Tetrahydrozoline is an imidazoline derivative with alpha receptor agonist activity widely available in over-the-counter topical ocular and nasal formulations... We report a case of unintentional tetrahydrozoline ingestion with cardiovascular effects persisting for 36 hours.
Pediatric Visine (tetrahydrozoline) ingestion: case report and review of imidazoline toxicity. [2003.08]
Visine, an over-the-counter, tetrahydrozoline topical ophthalmic decongestant, possesses central and peripheral alpha2-adrenergic properties. We present a case of accidental pediatric oral exposure with resultant neurological and cardiovascular complications... Over-the-counter medications with potent pharmacological properties should be stored in areas out of the reach of children, and manufacturers should package these products in childproof containers.
[The usage of nasal drops Tyzine in otorhinolaryngology] [1997]
In this research the authors presented their experiences in the treatment of non-complicated and complicated acute mucous membranous rhinitis with application of shrinking nasal drops Tyzine as a locally affective remedy assisting the therapy. The aim of this research was the estimation of the efficiency of Tyzine drops with mucous membranous rhinitis, their effect on the efficiency of the ciliary transport and stating the probable side effects occurring after their application...
Clinical Trials Related to Tyzine Pediatric (Tetrahydrozoline Nasal)
The Effect of "Eye Drop Guide" on the Success Rate of Eye Drops Self-instillation in Glaucoma Patients [Recruiting]
To investigate if the Eye Drop Guide more effective than carefully instructed routine
technique for chronic glaucoma patients to self-instill eye drops.
And what factors are associated with the failure of self-instillation eye drops with the Eye
Drop Guide?
Efficacy and Safety of Three Different Latanoprost 0,005% Eyedrops in Subjects Affected by Primary Open Angle Glaucoma [Recruiting]
The Effects of Ectoin� Allergy Nasal Spray and Ectoin� Allergy Eye Drops Compared to Placebo [Completed]
The primary objective of this study is to assess the relative efficacy of Ectoin® Allergy
Eye Drops and Ectoine® Allergy Nasal Spray compared to placebo, by evaluating Total Nasal
Symptom Score (TNSS) and Total Ocular Symptom Score (TOSS).
The secondary objectives are :
- To evaluate the relative efficacy of Ectoin® Allergy Eye Drops and Ectoin® Allergy
Nasal Spray compared to placebo by evaluating Total Non Nasal Symptom Score (TNNSS),
congestion symptom scores, red eye symptom scores, watery eye symptom scores, itchy
eye symptom scores, and by evaluating the mean cross-sectional area (MCA) using
acoustic rhinometry (AcR).
- To assess the change from baseline (post-EEC from pre-EEC) in inflammatory parameters
of nasal secretions, comparing Ectoin® Allergy Eye Drops and Ectoin® Allergy Nasal
Spray to placebo at each post-treatment visit.
Therapeutic Efficacy of APD-209 Eye Drops in Treatment of Epidemic Keratoconjunctivitis (EKC) [Recruiting]
Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease [Completed]
This study will evaluate the safety, efficacy, and acceptability of an eye drop formulation
in subjects with dry eye disease.
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