Tylenol with Codeine (Codeine / Acetaminophen) - Summary

SUMMARY

TYLENOL with Codeine (acetaminophen and codeine phosphate tablets and oral solution USP) combine the analgesic effects of a centrally acting analgesic, codeine, with a peripherally acting analgesic, acetaminophen.

TYLENOL with Codeine tablets (acetaminophen and codeine phosphate tablets) are indicated for the relief of mild to moderately severe pain.

TYLENOL with Codeine elixir (acetaminophen and codeine phosphate oral solution USP) is indicated for the relief of mild to moderate pain.

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NEWS HIGHLIGHTS RELATED TO TYLENOL WITH CODEINE

Published Studies Related to Tylenol with Codeine (Codeine / Acetaminophen)

A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery. [2008.03]

A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma. [2007.03]

The efficacy comparison of ibuprofen, acetaminophen-codeine, and placebo premedication therapy on the depth of anesthesia during treatment of inflamed teeth. [2006.09]

Comparison of oral versus rectal administration of acetaminophen with codeine in postoperative pediatric adenotonsillectomy patients. [2006.08]

Comparative trial of tramadol/paracetamol and codeine/paracetamol combination tablets on the vigilance of healthy volunteers. [2005.12]

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Clinical Trials Related to Tylenol with Codeine (Codeine / Acetaminophen)

Acetaminophen Adduct Formation in Non-Drinkers Taking Therapeutic Doses of Acetaminophen for Ten Consecutive Days [Completed]

A Trial Comparing Combination Therapy of Acetaminophen Plus Ibuprofen Versus Tylenol #3 for the Treatment of Pain After Outpatient Surgery [Completed]

Comparing Intravenous and Oral Paracetamol for Cholecystectomy [Completed]

The Effect of Paracetamol in the Treatment of Non-Severe Malaria in Children in Guinea-Bissau [Active, not recruiting]

A Study of the Efficacy and Safety of Tramadol HCl/Acetaminophen, Hydrocodone Bitartrate/Acetaminophen and Placebo in Patients With Pain From an Ankle Sprain With a Partial Torn Ligament [Completed]

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TYLENOL WITH CODEINE PATIENT REVIEWS / RATINGS / COMMENTS

Tylenol with Codeine review by 48 year old female patient
		Rating
Overall rating:
Effectiveness:		Considerably Effective
Side effects:		Severe Side Effects
		Treatment Info
Condition / reason:		pain after minor surgery
Dosage & duration:		one or two every 4 to 6 hrs (dosage frequency: one dose) for the period of one dose
Other conditions:		recovery from vein surgery
Other drugs taken:		none
		Reported Results
Benefits:		Due to extensive varicose veins, I was in pain, especially when standing. They were physically embarassing and I could not even wear sheer pantyhose. The surgery would eliminate pain and the ugliness. I was told to take the drug before surgery to minimize swelling and to minimize pain. I do not like to introduce drugs into my body unless an emergency so I did not take it before the surgery, instead opting for Bromelain enzyme, ginger and tumeric to reduce swelling.
Side effects:		The side effects after the surgery were swelling and pain and possibly infection at the incision sites. About 10 hours post surgery, the pain became unbearable, and I decided to take one dose of acetaminophen w/codeine #3. When I got up a couple of hours later to go and use the bathroom, I passed out in the bathroom. Lucky for me, my husband was nearby.
Comments:		I had a large vein stripped from my thigh and smaller ones in the leg, due to pain and discomfort I had been experiencing. It was an outpatient procedure that lasted about 2 hours.