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Tykerb (Lapatinib) - Current Clinical Trials

 
 



Tykerb Related Clinical Trials

Regulatory TYKERB´┐Ż Tablets PMS [Completed]

Lapatinib and Cetuximab in Patients With Solid Tumors [Completed]

A Phase II Trial of Lapatinib (TYKERB) + Pemetrexed (ALIMTA) in Advanced Non Small Cell Lung Cancer With an Initial Dose Finding Phase [Completed]

Capecitabine (Xeloda) and Lapatinib (Tykerb) as First-line Therapy in HER2/Neu-positive Breast Cancer [Active, not recruiting]

Lapatinib With Sirolimus or Metformin [Active, not recruiting]

Concentration and Activity of Lapatinib in Vestibular Schwannomas [Recruiting]

Neoadjuvant GW572016 to Treat Breast Cancer [Completed]

Lapatinib and Circulating Tumor Cells in Breast Cancer [Completed]

Preoperative Chemotherapy With Paclitaxel, Gemcitabine, and Lapatinib (Tykerb«) (PGT) [Completed]

Pazopanib, Lapatinib or Trastuzumab in Subjects With Solid Tumors [Completed]

LBH589 in Combination With Capecitabine Plus/Minus (´┐Ż) Lapatinib in Breast Cancer Patients [Completed]

Exploratory Lapatinib (Positron Emission Tomography) PET Study in Subjects With Breast Cancer [Completed]

A Study in Cancer Patients to Evaluate the Effect of Lapatinib on the QTc Interval [Completed]

Pilot Study of Veliparib (ABT-888) and Lapatinib (Tykerb) in Patients With Metastatic, Triple Negative Breast Cancer [Recruiting]

Drug Use Investigation for TYKERB Tablet (All Case Investigation) [Active, not recruiting]

A Phase I Study of Lapatinib (Tykerb) Plus Ixabepilone (Ixempra) as 2nd-line Treatment for Patients With HER-2 Overexpressed Recurrent or Persistent Endometrial Carcinoma or Carcinosarcoma [Enrolling by invitation]

Lapatinib In Combination With Trastuzumab Versus Lapatinib Monotherapy In Subjects With HER2-positive Metastatic Breast Cancer [Completed]

Akt Inhibitor MK2206 in Combination With Lapatinib Ditosylate in Patients With Advanced or Metastatic Solid Tumors or Breast Cancer [Completed]

Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma [Completed]

Lapatinib Tosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma [Suspended]

Lapatinib in Metastatic Breast Cancer Resistant to Hormone Therapy [Terminated]

Lapatinib Ditosylate and Akt Inhibitor MK2206 in Treating Women With Metastatic Breast Cancer [Active, not recruiting]

The Treatment of Lapatinib in Combination With Sorafenib in Patients With Advanced Refractory Solid Tumors [Completed]

Rollover Study Of Lapatinib In Cancer Patients [Completed]

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors [Completed]

Lapatinib in Combination With Weekly Paclitaxel in Patients With ErbB2 Amplified Advanced Gastric Cancer [Completed]

Neo ALTTO (Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Study [Active, not recruiting]

Entinostat, Lapatinib Ditosylate and Trastuzumab in Treating Patients With Locally Recurrent or Distant Relapsed Metastatic Breast Cancer Previously Treated With Trastuzumab Only [Recruiting]

Study To Examine The Effects Of Lapatinib On The Pharmacokinetics Of Digoxin In Subjects w/ ErbB2 Positive Breast Cancer [Completed]

Study to Assess dHER2+AS15 Cancer Vaccine Given in Combination With Lapatinib to Patients With Metastatic Breast Cancer [Completed]

A Phase I Study Of Oral Topotecan And Lapatinib In Subjects With Advanced Solid Tumors [Withdrawn]

Pazopanib (VOTRIENT) Plus Paclitaxel (TAXOL), Pazopanib Plus Paclitaxel (TAXOL) Plus Carboplatin (PARAPLATIN), and Pazopanib Plus Paclitaxel (TAXOL) Plus Lapatinib (TYKERB) [Completed]

Phase I Study of Ixabepilone Plus Lapatinib With or Without Capecitabine in the Treatment of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer [Terminated]

Phase II Lapatinib Plus Nab-Paclitaxel As First And Second Line Therapy In her2+ MBC [Active, not recruiting]

Lapatinib and Vinorelbine in Treating Patients With Advanced Solid Tumors [Completed]

Lapatinib Ditosylate in Treating Patients With a Rising PSA Indicating Recurrent Prostate Cancer [Completed]

Study of Lapatinib in Breast Cancer Patients With HER-2 Non-amplified Primary Tumors and HER-2 Positive or EGFR Positive Circulating Tumor Cells [Terminated]

Lapatinib and RAD-001 for HER2 Positive Metastatic Breast Cancer [Active, not recruiting]

Lapatinib and Capecitabine for Second Line Treatment of Pancreas Cancer [Terminated]

Lapatinib and Bevacizumab for Metastatic Breast Cancer [Active, not recruiting]

Lapatinib in Combination With Oral Vinorelbine for Metastatic Breast Cancer [Recruiting]

Lapatinib Ditosylate, Trastuzumab, Paclitaxel, and Surgery in Treating Patients With Breast Cancer [Completed]

Lapatinib and Temozolomide for the Treatment of Progressive Brain Disease in HER-2 Positive Breast Cancer [Completed]

Cabazitaxel Plus Lapatinib as Therapy for HER2-Positive Metastatic Breast Cancer Patients With Intracranial Metastases [Recruiting]

Lapatinib Ditosylate and Radiation Therapy in Treating Patients With Locally Advanced or Locally Recurrent Breast Cancer [Recruiting]

Phase II Study of Neoadjuvant XELOX + Lapatinib in HER2(+) Gastric Cancer Patients With Liver Metastasis [Recruiting]

Pazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Inflammatory Breast Cancer [Completed]

Akt Inhibitor MK2206, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With Locally Advanced or Metastatic HER2-Positive Breast , Gastric, or Gastroesophageal Cancer That Cannot Be Removed By Surgery [Terminated]

Dabrafenib and Lapatinib Ditosylate in Treating Patients With Refractory Thyroid Cancer That Cannot Be Removed by Surgery [Recruiting]

Tolerability of the Combination of Lapatinib and Trastuzumab in Adults Age 60 or Older With HER2 Positive Locally Advanced or Metastatic Breast Cancer [Recruiting]

Pazopanib In Combination With Lapatinib In Adult Patients With Relapsed Malignant Glioma [Completed]

Lapatinib in Combination With Radiation Therapy in Patients With Brain Metastases From HER2-Positive Breast Cancer [Completed]

Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors [Active, not recruiting]

GCC 0845:Vorinostat and Lapatinib in Advanced Solid Tumors and Advanced Breast Cancer to Evaluate Response and Biomarkers [Terminated]

Lapatinib Combined With Paclitaxel For Patients With First-Line ErbB2-Amplified Metastatic Breast Cancer [Completed]

A Study of Lapatinib in Combination With Everolimus in Patients With Advanced, Triple Negative Breast Cancer [Terminated]

Brain Metastases In ErbB2-Positive Breast Cancer [Terminated]

Lapatinib + Vinorelbine in ErbB2 Overexpressing, First or Second Line Metastatic Breast Cancer Subjects [Terminated]

Phase II Lapatinib and Radiation for Stage III-IV Head and Neck Cancer Patients Who Cannot Tolerate Concurrent Chemotherapy [Active, not recruiting]

A Study of Lapatinib in Combination With Caelyx in Patients With Advanced HER2 Positive Pretreated Breast Cancer [Recruiting]

Lapatinib Versus Placebo Given Concurrently With Cisplatin And Radiotherapy In Patients With Unresected Head And Neck Cancer [Completed]

Lapatinib in Combination With Docetaxel in Patients With HER-2 Positive Advanced or Metastatic Breast Cancer [Completed]

Lapatinib in Combination With Capecitabine in Japanese Patients With Metastatic Breast Cancer [Completed]

Lapatinib in Treating Patients With Recurrent or Metastatic Prostate Cancer [Completed]

Lapatinib Ditosylate in Treating Patients With Ductal Breast Carcinoma In Situ [Completed]

Neoadjuvant TDM1 With Lapatinib and Abraxane Compared With Trastuzumab With Lapatinib and Paclitaxel [Recruiting]

Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases [Completed]

Phase I/II Study of Lapatinib in Combination With Oxaliplatin and Capecitabine in Subjects With Advanced Colorectal Cancer [Completed]

Lapatinib +Capecitabine Treatment for Advanced Metastatic Breast Cancer in Women From China [Active, not recruiting]

Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer [Completed]

Lapatinib in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Peritoneal Cancer [Completed]

Lapatinib in Treating Patients With Recurrent or Persistent Endometrial Cancer [Completed]

Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast Cancer [Active, not recruiting]

Lapatinib in Treating Patients With Locally Advanced or Metastatic Biliary Tract or Liver Cancer That Cannot Be Removed By Surgery [Completed]

Lapatinib With Trastuzumab in Treating Patients With HER2-Negative/HER2 Mutant Metastatic Breast Cancer [Withdrawn]

Vinorelbine Metronomic Plus Lapatinib for Overexpressing HER-2 Metastatic Breast Cancer [Withdrawn]

Lapatinib in Treating Patients With Recurrent and/or Metastatic Adenoid Cystic Cancer or Other Salivary Gland Cancers [Completed]

Study Of Lapatinib In Patients With Relapsed Or Refractory Inflammatory Breast Cancer [Completed]

Safety Study in Subjects With Metastatic Breast Cancer Who Progressed After Taxanes Treatment. [Completed]

Short-term Presurgical Study to Assess Molecular Predictors of Lapatinib's Effects in Primary Breast Cancer [Completed]

Abraxane and Lapatinib in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer [Active, not recruiting]

Phase II Neoadjuvant in Inflammatory Breast Cancer [Terminated]

A Study Of Oral GW572016 In Advanced Or Metastatic Non-Small Cell Lung Cancer [Terminated]

Phase I/II Study of Lapatinib in Combination With Paclitaxel as 1L Chemotherapy for ErbB2-positive MBC [Completed]

Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma [Active, not recruiting]

To Examine The Effects Of Lapatinib On Orally And Intravenously Administered Midazolam In Cancer Patients [Completed]

Capecitabine, Cyclophosphamide, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With HER2-Positive Metastatic Breast Cancer [Recruiting]

Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS Metastasis [Recruiting]

Combination Of Lapatinib With Carboplatin, Paclitaxel and Trastuzumab In Metastatic Breast Cancer [Active, not recruiting]

Lapatinib and Tamoxifen in Treating Patients With Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Previous Tamoxifen [Completed]

GCC 0901 - Study of How Well Letrozole Works in Combination With Lapatinib Followed by an Addition of Everolimus in Postmenopausal Women With Advanced Endocrine Resistant Breast Cancer [Active, not recruiting]

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