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Trisenox (Arsenic Trioxide) - Published Studies

 


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Trisenox Related Published Studies

Well-designed clinical trials related to Trisenox (Arsenic Trioxide)

A phase I/II study of arsenic trioxide/bortezomib/ascorbic acid combination therapy for the treatment of relapsed or refractory multiple myeloma. [2007.03.15]

[Clinical observation and following up of two administration methods of arsenic trioxide in treatment of acute promyelocytic leukemia] [2004.03.02]

Combined treatment with arsenic trioxide and all-trans-retinoic acid in patients with relapsed acute promyelocytic leukemia. [2003.06.15]

[An analysis of the therapeutic effects and reactions in treating acute promyelocytic leukemia with intravenous arsenic trioxide or all-trans retinoic acid] [1999.02]

Well-designed clinical trials possibly related to Trisenox (Arsenic Trioxide)

All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. [2004.04.13]

Other research related to Trisenox (Arsenic Trioxide)

Arsenic trioxide and low-dose cytarabine in older patients with untreated acute myeloid leukemia, excluding acute promyelocytic leukemia. [2008.11.01]

Arsenic trioxide and 2-methoxyestradiol reduce beta-catenin accumulation after proteasome inhibition and enhance the sensitivity of myeloma cells to Bortezomib. [2008.11]

Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation. [2008.09]

Induction of apoptosis in arsenic trioxide-treated lung cancer A549 cells by buthionine sulfoximine. [2008.08.31]

Phase II clinical trial of arsenic trioxide with liposomal doxorubicin, vincristine, and dexamethasone in newly diagnosed multiple myeloma. [2008.08]

Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases. [2008.08]

Evaluation of arsenic trioxide-loaded albumin nanoparticles as carriers: preparation and antitumor efficacy. [2008.08]

Mineral arsenicals in traditional medicines: orpiment, realgar, and arsenolite. [2008.08]

Phase II study of arsenic trioxide and ascorbic acid for relapsed or refractory lymphoid malignancies: a Wisconsin Oncology Network study. [2008.07.31]

All-trans-retinoic acid and arsenic trioxide as initial therapy for acute promyelocytic leukemia. [2008.07]

Arsenic trioxide enhances the therapeutic efficacy of radiation treatment of oral squamous carcinoma while protecting bone. [2008.07]

Arsenic trioxide. [2008.07]

Mandibular bone necrosis caused by use of arsenic paste during endodontic treatment: two case reports. [2008.07]

Hyperleukocytosis from arsenic trioxide. [2008.06]

Acute renal failure, gastrointestinal bleeding, and cardiac arrhythmia after administration of arsenic trioxide for acute promyelocytic leukemia. [2008.05.15]

Arsenic trioxide-induced apoptosis in H9c2 cardiomyocytes: implications in cardiotoxicity. [2008.05]

Acute intestinal pseudo-obstruction after induction treatment of relapsed acute promyelocytic leukemia with arsenic trioxide. [2008.04]

Intravenous administration of arsenic trioxide encapsulated in liposomes inhibits the growth of C6 gliomas in rat brains. [2008.04]

Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases. [2008.04]

Safety and efficacy of arsenic trioxide for patients with advanced metastatic melanoma. [2008.03.01]

Arsenic trioxide, thalidomide and retinoid acid combination therapy in higher risk myelodysplastic syndrome patients. [2008.02]

Regulatory effects of mammalian target of rapamycin-mediated signals in the generation of arsenic trioxide responses. [2008.01.25]

Analytical artefacts in the speciation of arsenic in clinical samples. [2008.01.21]

Phase 1 trial and pharmacokinetic study of arsenic trioxide in children and adolescents with refractory or relapsed acute leukemia, including acute promyelocytic leukemia or lymphoma. [2008.01.15]

Comparative efficacy of two microdoses of a potentized homeopathic drug, arsenicum album, to ameliorate toxicity induced by repeated sublethal injections of arsenic trioxide in mice. [2008]

Insight into the selectivity of arsenic trioxide for acute promyelocytic leukemia cells by characterizing Saccharomyces cerevisiae deletion strains that are sensitive or resistant to the metalloid. [2008]

Phase II clinical trial of arsenic trioxide with liposomal doxorubicin, vincristine, and dexamethasone in newly diagnosed multiple myeloma. [2007.12.12]

Gene-mutation induction by arsenic compounds in the mouse lymphoma assay. [2007.12.01]

Using targeted magnetic arsenic trioxide nanoparticles for osteosarcoma treatment. [2007.12]

New data with arsenic trioxide in leukemias and myelodysplastic syndromes. [2007.12]

[Successful cyclosporine treatment for thrombocytopenia after salvage therapy with arsenic trioxide therapy followed by autologous hematopoietic stem cell transplantation in acute promyelocytic leukemia] [2007.12]

Arsenic in the cerebrospinal fluid of a patient receiving arsenic trioxide for relapsed acute promyelocytic leukemia with CNS involvement. [2007.11]

[Effect of bortezomib used alone or in combination with arsenic trioxide on HL-60 cell xenograft in nude mice] [2007.10]

Trolox enhances the anti-lymphoma effects of arsenic trioxide, while protecting against liver toxicity. [2007.10]

PML-RARalpha inhibitors (ATRA, tamibaroten, arsenic troxide) for acute promyelocytic leukemia. [2007.10]

Arsenical-based cancer drugs. [2007.10]

Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway. [2007.09.15]

A potentized homeopathic drug, Arsenicum Album 200, can ameliorate genotoxicity induced by repeated injections of arsenic trioxide in mice. [2007.09]

[Relationship between radiotherapy enhancing effect of arsenic trioxide and the proliferation and apoptosis of related protein in nasopharyngeal carcinoma patients] [2007.08]

Antimyeloma effects of arsenic trioxide are enhanced by melphalan, bortezomib and ascorbic acid. [2007.08]

PS-341 or a combination of arsenic trioxide and interferon-alpha inhibit growth and induce caspase-dependent apoptosis in KSHV/HHV-8-infected primary effusion lymphoma cells. [2007.08]

Impact of FLT3 mutations and secondary cytogenetic changes on the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with a single agent arsenic trioxide regimen. [2007.07]

Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: a paradigm of synergistic molecular targeting therapy. [2007.06.29]

[Organoarsenicals derived from 2-phenyl-[1,3,2]dithiarsolan-4-yl)-methanol (AsIII) with antileukaemic properties: from trypanosomicides to anticancer drugs] [2007.05]

Arsenic-induced APL differentiation in cerebrospinal fluid. [2007.05]

Combination therapy with arsenic trioxide, all-trans retinoic acid, and gemtuzumab ozogamicin in recurrent acute promyelocytic leukemia. [2007.04.01]

Osteomyelitis due to arsenic trioxide use for tooth devitalization. [2007.04]

Therapeutic effect of arsenic trioxide (As2O3) on cervical cancer in vitro and in vivo through apoptosis induction. [2007.04]

Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells. [2007.03]

Pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia treated with arsenic trioxide. [2007.03]

Synergistic therapeutic effect of arsenic trioxide and radiotherapy in BALB/C nude mice bearing nasopharyngeal carcinoma xenografts. [2007.03]

[Effects of controlled-release arsenic-trioxide-eluting stents on in-stent neointimal hyperplasia in coronary artery: experiment with dog model] [2007.02.27]

[Effects of controlled-release arsenic-trioxide-eluting stents on in-stent neointimal hyperplasia in coronary artery: experiment with dog model.] [2007.02.20]

Arsenic trioxide in patients with hepatocellular carcinoma: a phase II trial. [2007.02]

[Effects of arsenic trioxide on the autoimmunity and survival time in BXSB lupus mice] [2007.02]

Arsenic trioxide and neuroblastoma cytotoxicity. [2007.02]

Solid tumors subsequent to arsenic trioxide treatment for acute promyelocytic leukemia. [2007.01]

Combination treatment with arsenic trioxide and phytosphingosine enhances apoptotic cell death in arsenic trioxide-resistant cancer cells. [2007.01]

Arsenic trioxide and acute promyelocytic leukemia: clinical and biological. [2007]

A patient with progressive multiple myeloma treated successfully with arsenic trioxide after allogeneic bone marrow transplantation. [2007]

Arsenic trioxide/ascorbic acid therapy in patients with refractory metastatic colorectal carcinoma: A clinical experience. [2007]

Effect of arsenic trioxide on uveal melanoma cell proliferation in vitro. [2007]

[Two different clinical cases of acute arsenic trioxide intoxication] [2007]

Arsenic trioxide, a potent inhibitor of NF-kappaB, abrogates allergen-induced airway hyperresponsiveness and inflammation. [2006.12.20]

Arsenic trioxide: A promising novel therapeutic agent for lymphoproliferative and autoimmune syndromes in MRL/lpr mice. [2006.12.15]

Arsenic trioxide eluting stent reduces neointima formation in a rabbit iliac artery injury model. [2006.12.01]

Arsenic trioxide in hematological malignancies: the new discovery of an ancient drug. [2006.12]

Arsenic derivatives in hematologic malignancies: a role beyond acute promyelocytic leukemia? [2006.12]

Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation. [2006.11.15]

Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent down-regulation of survivin. [2006.11.15]

Optimizing treatment for elderly patients with acute promyelocytic leukemia: is it time to replace chemotherapy with all-trans retinoic acid and arsenic trioxide? [2006.11]

Arrhythmogenic effects of arsenic trioxide in patients with acute promyelocytic leukemia and an electrophysiological study in isolated guinea pig papillary muscles. [2006.11]

Effects of dietary arsenic levels on serum parameters and trace mineral retentions in growing and finishing pigs. [2006.11]

Arsenic compounds in the treatment of multiple myeloma: a new role for a historical remedy. [2006.11]

[Mechanisms of arsenic trioxide induced tumor cell apoptosis in myelodysplastic syndrome mice model in vivo] [2006.10]

Synergistic effect of arsenic trioxide and flt3 inhibition on cells with flt3 internal tandem duplication. [2006.10]

Efficacy and safety of melphalan, arsenic trioxide and ascorbic acid combination therapy in patients with relapsed or refractory multiple myeloma: a prospective, multicentre, phase II, single-arm study. [2006.10]

Real-time PCR analysis of PML-RAR alpha in newly diagnosed acute promyelocytic leukaemia patients treated with arsenic trioxide as a front-line therapy. [2006.10]

Inhibitory effect of arsenic trioxide on angiogenesis and expression of vascular endothelial growth factor in gastric cancer. [2006.09.28]

Anion exchanger 2 mediates the action of arsenic trioxide. [2006.09]

Arsonoliposomes: novel nanosized arsenic-containing vesicles for drug delivery. [2006.09]

Leukocytosis and retinoic acid syndrome in patients with acute promyelocytic leukemia treated with arsenic trioxide. [2006.09]

A phase I study to study arsenic trioxide with radiation and hyperthermia in advanced head and neck cancer. [2006.08]

A phase II trial of arsenic trioxide for relapsed and refractory acute lymphoblastic leukemia. [2006.08]

Down-regulation of wt1 expression in leukemia cell lines as part of apoptotic effect in arsenic treatment using two compounds. [2006.08]

Opposing effects of arsenic trioxide on hepatocellular carcinomas in mice. [2006.07]

Improved tumor destruction with arsenic trioxide and radiofrequency ablation in three animal models. [2006.07]

The efficacy of combined therapy of arsenic trioxide and alpha interferon in human T-cell leukemia virus type-1-infected squirrel monkeys (Saimiri sciureus). [2006.07]

Southwest Oncology Group phase II study of arsenic trioxide in patients with refractory germ cell malignancies. [2006.06.15]

[Preliminary report of combination chemotherapy including Arsenic trioxide for stage III osteosarcoma and Ewing sarcoma] [2006.06.15]

Phase II multicenter study of arsenic trioxide in patients with myelodysplastic syndromes. [2006.06.01]

Arsenic trioxide in patients with myelodysplastic syndromes: a phase II multicenter study. [2006.06.01]

Optimization of combination therapy of arsenic trioxide and fractionated radiotherapy for malignant glioma. [2006.06.01]

Effects of arsenic trioxide administration styles on leukocytosis. [2006.06]

Use of all-trans retinoic acid plus arsenic trioxide as an alternative to chemotherapy in untreated acute promyelocytic leukemia. [2006.05.01]

Recurrent extramedullary relapse of acute promyelocytic leukemia after allogeneic stem cell transplantation: successful treatment by arsenic trioxide in combination with local radiotherapy. [2006.05]

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