TRILYTE is a white powder for reconstitution containing 420 g polyethylene glycol 3350, 5.72 g sodium bicarbonate, 11.2 g sodium chloride, 1.48 g potassium chloride. Flavor packs, each containing 3.22 g of flavoring ingredients, are attached to the 4 liter bottle.
TRILYTE (POLYETHYLENE GLYCOL 3350/SODIUM CATION/SODIUM CATION/POTASSIUM CATION) is indicated for the following:
Media Articles Related to Trilyte (Polyethylene Glycol 3350)
Edible Bowel Prep Pleases Patients
Source: Medscape Gastroenterology Headlines [2016.10.18]
An edible bowel preparation developed with the input of research chefs was highly rated by patients in a phase 2 study, and could lead to a boost in colonoscopy screening rates.
Medscape Medical News
Published Studies Related to Trilyte (Polyethylene Glycol 3350)
A randomised, double-blind study of polyethylene glycol 4000 and lactulose in the
treatment of constipation in children. 
treatment of chronic constipation in young children... CONCLUSIONS: PEG 4000 has superior efficacy to lactulose for the treatment of
Reduced cathartic bowel preparation for CT colonography: prospective comparison of 2-L polyethylene glycol and magnesium citrate. [2011.10]
PURPOSE: To prospectively compare adequacy of colonic cleansing, adequacy of solid stool and fluid tagging, and patient acceptance by using reduced-volume, 2-L polyethylene glycol (PEG) versus magnesium citrate bowel preparations for CT colonography... CONCLUSION: Reduced-volume PEG and magnesium citrate bowel preparations demonstrated adequate cleansing effectiveness for CT colonography, with better tagging and shorter interpretation time observed in the PEG group. Adequate polyp detection was maintained but requires further validation because of the small number of clinically important polyps. (c) RSNA, 2011.
Effect of bowel preparation with polyethylene glycol on quality of capsule endoscopy. [2011.06]
BACKGROUND AND AIMS: Capsule endoscopy (CE) has the problem that lumen visualization is impaired by bubbles, bile, and debris. The benefits of bowel preparation are still controversial and the best method remains to be determined. The objective of this study was to evaluate the effect of the method of bowel preparation on the quality of visualization and on transit time... CONCLUSIONS: Bowel preparation with PEG resulted in better image quality than fasting alone. No significant difference was observed between 2 and 4 l. PEG 2 l rather than 4 l may be a useful method of preparation for CE.
Low-volume bowel preparation is inferior to standard 4 1 polyethylene glycol. [2011.03]
BACKGROUND: Four liters or more of orally taken polyethylene glycol solution (PEG) has proved to be an effective large-bowel cleansing method prior to colonoscopy. The problem has been the large volume of fluid and its taste, which is unacceptable to some examinees. We aimed to investigate the effectiveness of 2 l PEG combined with senna compared with 4 l PEG for bowel preparation... CONCLUSIONS: 4 l PEG treatment is better than 36 mg senna and 2 l PEG as routine colonic cleansing before colonoscopy because of fewer failures.
Comparison of the effectiveness of polyethylene glycol 4000 without electrolytes and magnesium hydroxide in the treatment of chronic functional constipation in children. [2011.01]
OBJECTIVE: To compare the effectiveness of two drugs, polyethylene glycol 4000 without electrolytes and magnesium hydroxide, in the treatment of chronic functional constipation in children... CONCLUSION: The two laxatives showed no difference in effectiveness for the treatment of constipation. However, due to its better acceptance, because it is odorless and tasteless, polyethylene glycol proved to be a better option for treating chronic functional constipation.
Clinical Trials Related to Trilyte (Polyethylene Glycol 3350)
Gatorade/Miralax With or Without Bisacodyl Versus NuLytely for Colonoscopy Preparation [Completed]
The purpose of this study is to compare Nulytely (or Trilyte) with a Gatorade and Miralax
combination for cleaning out the colon before colonoscopy. A laxative pill called Bisacodyl
may also be used with the Gatorade and Miralax to see if it helps with the clean out
process. We are trying to find out if either of these methods is more acceptable to the
patient and does a better job cleaning out the colon for a colonoscopy.
MoviPrepï¿½ Versus HalfLytelyï¿½, Low-VolUme PEG Solutions for Colon Cleansing: An InvesTigator-blindEd, Randomized, Trial [Completed]
A properly prepared colon is vital to the success of any colonoscopy. The purpose of this
study is to determine which colon prep, MoviPrep or HalfLytely is the superior prepping
HalfLytely Bowel Prep System for Colonoscopy [Completed]
The purpose of the this study was to compare the safety and efficacy of HalfLytely (2L
NULYTELY + 20mg bisacodyl) to NULYTELY for preparation prior to colonoscopy.
Evaluation Of The Efficacy Of HalfLYTELY For Bowel Cleansing Before Virtual Colonoscopy and Conventional Colonoscopy. [Completed]
To evaluate the efficacy of standard HalfLYTELY® as a bowel cleansing preparation for adult
patients undergoing virtual colonoscopy (VC).
Safety and Efficacy of OsmoPrep® Tablets Versus HalfLytely® and Bisacodyl Tablet Bowel Prep Kit for Colon Cleansing [Active, not recruiting]
The purpose of this study is to compare the safety and efficacy of OsmoPrep tablets versus
HalfLytely and Bisacodyl Tablet Bowel Prep Kit in subjects who are undergoing colonoscopy.