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Triaz (Benzoyl Peroxide Topical) - Summary

 
 



TRIAZ SUMMARY

TRIAZ® (benzoyl peroxide) 3%, 6%, and 9% Gels, TRIAZ® (benzoyl peroxide) 3%, 6%, and 9% Cleansers and TRIAZ® (benzoyl peroxide) 3%, 6%, and 9% Pads are topical, gel-based, benzoyl peroxide containing preparations for use in the treatment of acne vulgaris. Benzoyl peroxide is an oxidizing agent that possesses antibacterial properties and is classified as a keratolytic.

TRIAZ 3%, 6%, and 9% Gels, TRIAZ 3%, 6%, and 9% Cleansers and TRIAZ 3%, 6%, and 9% Pads are indicated for the topical treatment of acne vulgaris.


See all Triaz indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Triaz (Benzoyl Peroxide)

Health Tip: Avoiding Acne Triggers
Source: MedicineNet Acne Specialty [2014.03.18]
Title: Health Tip: Avoiding Acne Triggers
Category: Health News
Created: 3/18/2014 7:35:00 AM
Last Editorial Review: 3/18/2014 12:00:00 AM

Health Tip: Taming Acne
Source: MedicineNet Acne Specialty [2014.01.10]
Title: Health Tip: Taming Acne
Category: Health News
Created: 1/10/2014 7:35:00 AM
Last Editorial Review: 1/10/2014 12:00:00 AM

Clear Skin Pictures Slideshow: Helping Your Teen With Acne
Source: MedicineNet Boils Specialty [2013.11.07]
Title: Clear Skin Pictures Slideshow: Helping Your Teen With Acne
Category: Slideshows
Created: 1/20/2010 3:54:00 PM
Last Editorial Review: 11/7/2013 12:00:00 AM

Acne (Pimples)
Source: MedicineNet Boils Specialty [2013.08.13]
Title: Acne (Pimples)
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 8/13/2013 12:00:00 AM

Pediatricians Endorse New Acne Treatment Guidelines
Source: MedicineNet isotretinoin Specialty [2013.05.06]
Title: Pediatricians Endorse New Acne Treatment Guidelines
Category: Health News
Created: 5/6/2013 10:35:00 AM
Last Editorial Review: 5/6/2013 12:00:00 AM

more news >>

Published Studies Related to Triaz (Benzoyl Peroxide)

Fitzpatrick skin types and clindamycin phosphate 1.2%/benzoyl peroxide gel: efficacy and tolerability of treatment in moderate to severe acne. [2012]
efficacy of acne medications in skin of color... CONCLUSIONS: Acne subjects with Fitzpatrick skin types IV-VI were not found to be

Treatment of moderate to severe acne vulgaris in a Hispanic population: a post-hoc analysis of efficacy and tolerability of clindamycin phosphate 1.2%/benzoyl peroxide 2.5% gel. [2012]
in Hispanics... CONCLUSIONS: Overall efficacy and tolerability with clindamycin phosphate

Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: A randomized controlled trial. [2011.11]
BACKGROUND: Topical therapy with comedolytics and antibiotics are often advocated for mild and moderate severity acne vulgaris. Nadifloxacin, a new fluoroquinolone with anti-Propionibacterium acnes activity and additional anti-inflammatory activity, is approved for use in acne. This randomized controlled assessor blind trial compared the clinical effectiveness and safety of eight weeks therapy of nadifloxacin 1% versus clindamycin 1% as add-on therapy to benzoyl peroxide (2.5%) in mild to moderate grade acne... CONCLUSIONS: Topical nadifloxacin, a new fluoroquinolone is effective, tolerable, and safe for mild o moderate facial acne. Its clinical effectiveness is comparable to clindamycin when used as add-on therapy to benzoyl peroxide.

Combination therapy with adapalene-benzoyl peroxide and oral lymecycline in the treatment of moderate to severe acne vulgaris: a multicentre, randomized, double-blind controlled study. [2011.08]
BACKGROUND: Oral antibiotics in association with a topical retinoid with or without benzoyl peroxide (BPO) are the recommended first-line option in the treatment of moderate to severe acne vulgaris. OBJECTIVES: To evaluate the efficacy and safety of oral lymecycline 300 mg with adapalene 0.1%-BPO 2.5% (A/BPO) fixed-dose gel in comparison with oral lymecycline 300 mg with a vehicle gel in subjects with moderate to severe acne vulgaris... CONCLUSION: These results demonstrate the clinical benefit of combining A/BPO with lymecycline in the treatment of moderate to severe acne vulgaris. (c) 2011 The Authors. BJD (c) 2011 British Association of Dermatologists 2011.

A 6-month maintenance therapy with adapalene-benzoyl peroxide gel prevents relapse and continuously improves efficacy among patients with severe acne vulgaris: results of a randomized controlled trial. [2011.06]
BACKGROUND: Acne vulgaris is a chronic and frequently recurring disease. A fixed-dose adapalene-benzoyl peroxide (adapalene-BPO) gel is an efficacious and safe acne treatment. OBJECTIVES: To assess the long-term effect of adapalene-BPO on relapse prevention among patients with severe acne after successful initial treatments... CONCLUSIONS: Adapalene-BPO not only prevents the occurrence of relapse among patients with severe acne, but also continues to reduce disease symptoms during 6 months. (c) 2011 The Authors. BJD (c) 2011 British Association of Dermatologists.

more studies >>

Clinical Trials Related to Triaz (Benzoyl Peroxide)

Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris [Completed]
This is a multi-center, randomized, double-blind, parallel group study with 12 weeks of treatment of acne vulgaris. Efficacy and safety evaluations will be performed at Screening (safety only), Baseline and Weeks 1, 2, 4, 8 and 12. All Investigator's Global Assessment evaluators and lesion counters must be trained and approved by Galderma. The evaluator of a subject should remain the same during the study.

The primary objective is to demonstrate the superiority in efficacy and assess safety of adapalene/benzoyl peroxide topical gel (adapalene/benzoyl peroxide gel) versus adapalene topical gel, 0. 1% (adapalene monad); benzoyl peroxide topical gel, 2. 5% (benzoyl peroxide monad) and topical gel vehicle (gel vehicle) in the treatment of acne vulgaris for up to 12 weeks.

A Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris [Completed]
This is a multi-center, randomized, double-blind, parallel group study with 12 weeks of treatment of acne vulgaris. Efficacy and safety evaluations will be performed at Screening (safety only), Baseline and Weeks 1, 2, 4, 8 and 12. All Investigator's Global Assessment evaluators and lesion counters must be trained and approved by Galderma. The evaluator of a subject should remain the same during the study.

The primary objective is to demonstrate the superiority in efficacy and assess safety of Adapalene/Benzoyl Peroxide Topical Gel (Adapalene/Benzoyl Peroxide Gel) versus Adapalene Topical Gel, 0. 1% (Adapalene Monad); Benzoyl Peroxide Topical Gel, 2. 5% (Benzoyl Peroxide Monad) and Topical Gel Vehicle (Gel Vehicle) in the treatment of acne vulgaris for up to 12 weeks.

Study of Benzoyl Peroxide Cream for Mild to Moderate Acne Vulgaris [Completed]

Efficacy and Tolerance of a Derivative of Salicylic Acid and 5% Benzoyl Peroxide in Facial Acne Vulgaris [Completed]
Acne vulgaris is a frequent inflammatory skin condition involving the pilosebaceous unit and affecting more than 80% of teenagers. Mild to moderate acne vulgaris is usually treated with topical agents such as benzoyl peroxide, retinoids and antibiotics. These treatments can be associated with local tolerance problems and/or antibiotic resistance. Salicylic acid has been shown to be an effective treatment for acne. LHA is a lipophilic hydroxy acid derivative of salicylic acid that has comedolytic and antibacterial properties.

The objective of this trial was to compare the efficacy and tolerance of a cream formulation containing 0. 3% LHA (LHA formulation) to a 5% benzoyl peroxide gel.

A Study Comparing Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel to Duac´┐Ż Topical Gel in the Treatment of Acne Vulgaris [Recruiting]
The objective of this study is to compare the relative efficacy and safety of the test formulation Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Taro Pharmaceuticals Inc.) to the marketed formulation Duac« Topical Gel (Clindamycin 1%/Benzoyl Peroxide 5%) (Stiefel) in the treatment of the inflamed lesions of acne vulgaris. Both the test and reference formulations will also be compared to a placebo formulation to test for superiority.

more trials >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 4 ratings/reviews, Triaz has an overall score of 8.25. The effectiveness score is 8.50 and the side effect score is 8. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
 

Triaz review by 27 year old female patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   Acne
Dosage & duration:   apply every night for 6 months (dosage frequency: apply every night for 6 months) for the period of 6 months
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   My spots were reduced dramacially, skin cleared up and felt better. my confidence improved. i would recommend this product to other people.
Side effects:   very slight dry skin in the areas I used the gel the most.
Comments:   I had to apply gel each night and keep it on whilst asleep, I would wash off in the morning and use other products as normal.

 

Triaz review by 28 year old male patient

  Rating
Overall rating:  
Effectiveness:   Moderately Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   acne
Dosage & duration:   10% (dosage frequency: daily) for the period of on and off 7 yrs
Other conditions:   dry skin
Other drugs taken:   nothing
  
Reported Results
Benefits:   The acne cleared up for a while but soon after discontinuing use it would return. It reduced breakouts significantly.
Side effects:   Dry irritated skin and burning. Over many years loss of elasticity and slight damage to the skin.
Comments:   The treatment was to cover entire affected area twice daily until acne cleared up. Was not supposed to use any other topical treatments with the cream.

 

Triaz review by 28 year old male patient

  Rating
Overall rating:  
Effectiveness:   Moderately Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   acne
Dosage & duration:   10% (dosage frequency: daily) for the period of on and off 7 yrs
Other conditions:   dry skin
Other drugs taken:   nothing
  
Reported Results
Benefits:   The acne cleared up for a while but soon after discontinuing use it would return. It reduced breakouts significantly.
Side effects:   Dry irritated skin and burning. Over many years loss of elasticity and slight damage to the skin.
Comments:   The treatment was to cover entire affected area twice daily until acne cleared up. Was not supposed to use any other topical treatments with the cream.

See all Triaz reviews / ratings >>

Page last updated: 2014-03-18

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