Trelstar Depot (Triptorelin Pamoate) - Summary

TRELSTAR DEPOT SUMMARY

B1
Revised: September 2005
Watson Pharma, Inc.
TRELSTAR^® DEPOT 3.75 mg
(triptorelin pamoate for injectable suspension)

TRELSTAR DEPOT contains a pamoate salt of triptorelin, and triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH or GnRH) with greater potency than the naturally occurring LHRH.

TRELSTAR DEPOT is indicated in the palliative treatment of advanced prostate cancer. It offers an alternative treatment for prostate cancer when orchiectomy or estrogen administration are either not indicated or unacceptable to the patient.

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TRELSTAR DEPOT NEWS HIGHLIGHTS

Media Articles Related to Trelstar Depot (Triptorelin)

Prostate Cancer Promotes The Growth Of New Nerves And The Branching Axons That Carry Their Messages
Source: Health News from Medical News Today [2008.12.01]

Dynamic Change In Phosphorylated PDGFR In Peripheral Blood Leukocytes After Docetaxel Therapy Predicts Overall Survival In Prostate Cancer
Source: Cancer / Oncology News From Medical News Today [2008.12.01]

Plumbagin, A Medicinal Plant-Derived Naphthoquinone, Is A Novel Inhibitor Of The Growth And Invasion Of Hormone-Refractory Prostate Cancer
Source: Cancer / Oncology News From Medical News Today [2008.12.01]

Prostate cancer radiotherapy safe for HIV patients (Reuters)
Source: Y! Health Cancer & Chemotherapy News [2008.12.01]

Age And Grade Trends In Prostate Cancer (1974-2003): A Surveillance, Epidemiology, And End Results Registry Analysis
Source: Cancer / Oncology News From Medical News Today [2008.11.30]

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Published Studies Related to Trelstar Depot (Triptorelin)

A randomized study comparing triptorelin or expectant management following conservative laparoscopic surgery for symptomatic stage III-IV endometriosis. [2008.02]

Endocrine effects of adjuvant letrozole + triptorelin compared with tamoxifen + triptorelin in premenopausal patients with early breast cancer. [2008.01.10]

Clinical outcome with half-dose depot triptorelin is the same as reduced-dose daily buserelin in a long protocol of controlled ovarian stimulation for ICSI/embryo transfer: a randomized double-blind clinical trial (NCT00461916). [2007.09]

[Multicentre randomized trial comparing triptorelin medical castration versus surgical castration in the treatment of locally advanced or metastatic prostate cancer] [2007.04]

A randomized study comparing triptorelin or expectant management following conservative laparoscopic surgery for symptomatic stage III-IV endometriosis. [2006.12.16]

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Clinical Trials Related to Trelstar Depot (Triptorelin)

Study to Assess the Non-Inferiority of Pamorelin® 11,25mg SC Injected Versus Pamorelin® 11,25mg IM Injected in Patients Suffering From Advanced Prostate Cancer (PAMOJECT) [Recruiting]

Decapeptyl SR With Livial Add Back Therapy in the Management of Chronic Cyclical Pelvic Pain in Pre Menopausal Women [Not yet recruiting]

Half-Dose Depot Triptorelin Versus Reduced-Dose Daily Buserelin [Completed]

Efficacy and Safety Study of Pamoate of Triptorelin in Children With Precocious Puberty [Recruiting]

Study to Evaluate a Subcutaneous Four Months Sustained-Release Formulation of Triptorelin in Patients With Prostate Cancer [Terminated]

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