DESCRIPTION
Chemically, TRANXENE is a benzodiazepine. The empirical formula is C16H11ClK2N2O4; the molecular weight is 408.92; and the structural formula may be represented as follows:
The compound occurs as a fine, light yellow, practically odorless powder. It is insoluble in the common organic solvents, but very soluble in water. Aqueous solutions are unstable, clear, light yellow, and alkaline.
TRANXENE T-TAB tablets contain either 3.75 mg, 7.5 mg or 15 mg of clorazepate dipotassium for oral administration. TRANXENE-SD and TRANXENE-SD HALF STRENGTH tablets contain 22.5 mg and 11.25 mg of clorazepate dipotassium respectively. TRANXENE-SD and TRANXENE-SD HALF STRENGTH tablets gradually release clorazepate and are designed for once-a-day administration in patients already stabilized on TRANXENE T-TAB tablets.
Inactive ingredients for TRANXENE T-TAB® Tablets: Colloidal silicon dioxide, FD&C Blue No. 2 (3.75 mg only), FD&C Yellow No. 6 (7.5 mg only), FD&C Red No. 3 (15 mg only), magnesium oxide, magnesium stearate, microcrystalline cellulose, potassium carbonate, potassium chloride, and talc. Inactive ingredients for TRANXENE-SD and TRANXENE-SD HALF STRENGTH Tablets: Castor oil wax, FD&C Blue No. 2 (SD Half Strength, 11.25 mg only), iron oxide (SD, 22.5 mg only), lactose, magnesium oxide, magnesium stearate, potassium carbonate, potassium chloride, and talc.
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