Trandate (Labetalol Hydrochloride) - Summary

TRANDATE SUMMARY

TRANDATE^®
(labetalol hydrochloride)
Tablets

TRANDATE Tablets are adrenergic receptor blocking agents that have both selective alpha₁-adrenergic and nonselective beta-adrenergic receptor blocking actions in a single substance.

TRANDATE Tablets are indicated in the management of hypertension. TRANDATE Tablets may be used alone or in combination with other antihypertensive agents, especially thiazide and loop diuretics.

TRANDATE NEWS HIGHLIGHTS

Published Studies Related to Trandate (Labetalol)

Benzodiazepine and opioid sedation attenuate the sympathetic response to fiberoptic bronchoscopy. Prophylactic labetalol gave no additional benefit. Results of a randomized double-blind placebo-controlled study. [2008.07]

Management of severe hypertension in the postpartum period with intravenous hydralazine or labetalol: a randomized clinical trial. [2007]

Severe hypertension in pregnancy: hydralazine or labetalol. A randomized clinical trial. [2006.09]

Pharmacokinetic interaction studies of atosiban with labetalol or betamethasone in healthy female volunteers. [2005.11]

Labetalol treatment enhances the attenuation of tobacco withdrawal symptoms by nicotine in abstinent smokers. [2003.12]

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Clinical Trials Related to Trandate (Labetalol)

Labetalol Versus MgSO4 for the Prevention of Eclampsia Trial [Recruiting]

Effects of Labetalol on Human Cocaine Use - 8 [Completed]

Effects of Labetalol on Nicotine Administration in Humans - 14 [Completed]

Labetalol to Prevent Hypertension and Tachycardia During Fiberoptic Bronchoscopy [Completed]

Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage [Completed]

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