TRAMADOL HYDROCHLORIDE TABLETS
Description
Tramadol hydrochloride tablet is a centrally acting analgesic. The chemical
name for tramadol hydrochloride is (+) cis- 2-[(dimethylamino)methyl]-
1-(3-methoxyphenyl)cyclohexanol hydro c hloride and it has the molecular formula of C16H25NO2.HCl. Its structural formula is:
The molecular weight of tramadol hydrochloride is 299.8. Tramadol hydrochloride is a white, bitter, crystalline and odorless powder. It is readily soluble in water and ethanol and has a pKa of 9.41. The n-octanol/ water log partition coefficient (logP) is 1.35 at pH 7. Tramadol hydrochloride tablets contain 50 mg of tramadol hydrochloride. In addition, each tablet contains the following inactive ingredients: hypromellose, lactose monohydrate, magnesium stearate, maize starch, microcrystalline cellulose, polyethylene
glycol, sodium starch glycolate and titanium dioxide
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