Toprol-XL Related Published Studies
Well-designed clinical trials related to Toprol-XL (Metoprolol)
Effect of metoprolol on quality of life in the prevention of syncope trial. [2009.10]
Beta-receptor selectivity of carvedilol and metoprolol succinate in patients with heart failure (SELECT trial): a randomized dose-ranging trial. [2009.08]
Antihypertensive efficacy of metoprolol XL/low dose chlorthalidone (6.25 mg) combination: a randomized, comparative study in indian patients with mild-to-moderate essential hypertension. [2009.07.22]
Prevention of perioperative atrial fibrillation with betablockers in coronary surgery: betaxolol versus metoprolol. [2009.07]
The influence of renal function on clinical outcome and response to beta-blockade in systolic heart failure: insights from Metoprolol CR/XL Randomized Intervention Trial in Chronic HF (MERIT-HF). [2009.05]
Influence of metoprolol on systolic and diastolic function in children with heart failure. [2009.03.01]
The calcium channel blocker felodipine attenuates the positive hemodynamic effects of the beta-blocker metoprolol in severe dilated cardiomyopathy--a prospective, randomized, double-blind and placebo-controlled study with invasive hemodynamic assessment. [2009.02.20]
Erectile dysfunction after therapy with metoprolol: the hawthorne effect. [2009]
[Comparison of metoprolol vs clonazepam as a first treatment choice among patients with neurocardiogenic syncope] [2008.11]
Demographic analyses of the effects of carvedilol vs metoprolol on glycemic control and insulin sensitivity in patients with type 2 diabetes and hypertension in the Glycemic Effects in Diabetes Mellitus: Carvedilol-Metoprolol Comparison in Hypertensives (GEMINI) study. [2008.09]
A randomized, double-blind study of valsartan versus metoprolol on arterial distensibility and endothelial function in essential hypertension. [2008.07]
[Effects of metoprolol on perioperative cardiovascular events in patients with risk or at high risk for coronary artery disease undergoing non-cardiac surgery] [2008.06.03]
Randomized comparison of metoprolol versus conventional treatment in preventing recurrence of vasovagal syncope in children and adolescents. [2008.04]
Comparison of the effects of carvedilol and metoprolol on exercise ventilatory efficiency in patients with congestive heart failure. [2008.03]
Renal and cardiac effects of antihypertensive treatment with ramipril vs metoprolol in autosomal dominant polycystic kidney disease. [2008.02]
Nebivolol and metoprolol for treating migraine: an advance on beta-blocker treatment? [2008.01]
[Controlled release metoprolol succinate in MERIT-HF. Analysis of patients subgroups] [2008]
Both clonidine and metoprolol modify anesthetic depth indicators and reduce intraoperative propofol requirement. [2008]
Effect of nebivolol and metoprolol treatments on serum asymmetric dimethylarginine levels in hypertensive patients with type 2 diabetes mellitus. [2007.12]
Effect of carvedilol and metoprolol on the mode of death in patients with heart failure. [2007.11]
Effect of beta-blocker therapy on left atrial function in patients with heart failure: comparison of metoprolol succinate with carvedilol. [2007.10]
Optimal beta-blocker for prevention of atrial fibrillation after on-pump coronary artery bypass graft surgery: carvedilol versus metoprolol. [2007.09]
Central mechanisms of controlled-release metoprolol in migraine: a double-blind, placebo-controlled study. [2007.09]
Effects of metoprolol and carvedilol on pre-existing and new onset diabetes in patients with chronic heart failure: data from the Carvedilol Or Metoprolol European Trial (COMET). [2007.08]
Prognostic importance of plasma NT-pro BNP in chronic heart failure in patients treated with a beta-blocker: results from the Carvedilol Or Metoprolol European Trial (COMET) trial. [2007.08]
Metoprolol reverses left ventricular remodeling in patients with asymptomatic systolic dysfunction: the REversal of VEntricular Remodeling with Toprol-XL (REVERT) trial. [2007.07.03]
Randomized active-controlled study comparing effects of treatment with carvedilol versus metoprolol in patients with left ventricular dysfunction after acute myocardial infarction. [2007.07]
Effects of carvedilol versus metoprolol on endothelial function and oxidative stress in patients with type 2 diabetes mellitus. [2007.07]
Pronounced improvement in systolic and diastolic ventricular long axis function after treatment with metoprolol. [2007.06]
Maintenance of sinus rhythm with metoprolol CR initiated before cardioversion and repeated cardioversion of atrial fibrillation: a randomized double-blind placebo-controlled study. [2007.06]
Effects of nebivolol on platelet activation in hypertensive patients: a comparative study with metoprolol. [2007.03.20]
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET. [2007.03.06]
Effect of diltiazem and metoprolol on left atrial appendix functions in patients with nonvalvular chronic atrial fibrillation. [2007.03]
Efficacy and safety of extended release metoprolol succinate in hypertensive children 6 to 16 years of age: a clinical trial experience. [2007.02]
Acute hemodynamic effects of moderate doses of nebivolol versus metoprolol in patients with systolic heart failure. [2007.02]
Carvedilol in the treatment of chronic heart failure: lessons from the Carvedilol Or Metoprolol European Trial. [2007]
Compliance, clinical outcome, and quality of life of patients with stable angina pectoris receiving once-daily betaxolol versus twice daily metoprolol: a randomized controlled trial. [2007]
Comparative bioavailability of metoprolol tartrate after oral and transdermal administration in healthy male volunteers. [2007]
The effects of perioperative beta-blockade: results of the Metoprolol after Vascular Surgery (MaVS) study, a randomized controlled trial. [2006.11]
Effectiveness and tolerability of acupuncture compared with metoprolol in migraine prophylaxis. [2006.11]
Randomized, double-blind comparison of acute beta1-blockade with 50 mg metoprolol tartrate vs 25 mg carvedilol in normal subjects. [2006.09]
Valdecoxib does not interfere with the CYP2D6 substrate metoprolol. [2006.09]
Rationale, design, and organization of the PeriOperative ISchemic Evaluation (POISE) trial: a randomized controlled trial of metoprolol versus placebo in patients undergoing noncardiac surgery. [2006.08]
Intravenous administration of metoprolol is more effective than oral administration in the prevention of atrial fibrillation after cardiac surgery. [2006.07.04]
Carvedilol versus Metoprolol for the prevention of atrial fibrillation after off-pump coronary bypass surgery: rationale and design of the Carvedilol or Metoprolol Post-Revascularization Atrial Fibrillation Controlled Trial (COMPACT). [2006.06]
A comparison of the effects of carvedilol and metoprolol on well-being, morbidity, and mortality (the "patient journey") in patients with heart failure: a report from the Carvedilol Or Metoprolol European Trial (COMET). [2006.04.18]
A factorial study of combination hypertension treatment with metoprolol succinate extended release and felodipine extended release results of the Metoprolol Succinate-Felodipine Antihypertension Combination Trial (M-FACT). [2006.04]
[Influences of perioperative metoprolol on hemodynamics and myocardial ischaemia in elderly patients undergoing noncardiac surgery] [2006.04]
Sustained restoration of autonomic balance with long- but not short-acting metoprolol in patients with heart failure. [2006.04]
Modulated release metoprolol succinate formulation based on ionic interactions: in vivo proof of concept. [2006.03.10]
Prevention of Syncope Trial (POST): a randomized, placebo-controlled study of metoprolol in the prevention of vasovagal syncope. [2006.03.07]
Effects of metoprolol therapy on cardiac troponin-I levels after elective percutaneous coronary interventions. [2006.03]
Comparative effects of nebivolol and metoprolol on oxidative stress, insulin resistance, plasma adiponectin and soluble P-selectin levels in hypertensive patients. [2006.03]
Introduction of metoprolol increases plasma B-type cardiac natriuretic peptides in mild, stable heart failure. [2006.02.21]
After myocardial infarction carvedilol improves insulin resistance compared to metoprolol. [2006.02]
Comparison of carvedilol and metoprolol in patients with acute myocardial infarction undergoing primary coronary intervention--the PASSAT Study. [2006.01]
The use of metoprolol CR/XL in the treatment of patients with diabetes and chronic heart failure. [2006]
Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial. [2005.11.05]
Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial. [2005.11]
Carvedilol exerts more potent antiadrenergic effect than metoprolol in heart failure. [2005.10]
Felodipine-metoprolol combination tablet: maintained health-related quality of life in the presence of substantial blood pressure reduction. [2005.10]
Carvedilol improves myocardial contractility compared with metoprolol in patients with chronic hibernating myocardium after revascularization. [2005.09]
Metoprolol prevents sodium retention induced by lower body negative pressure in healthy men. [2005.08]
Comparison of the effectiveness of intravenous diltiazem and metoprolol in the management of rapid ventricular rate in atrial fibrillation. [2005.06]
Modulation of metoprolol pharmacokinetics and hemodynamics by diphenhydramine coadministration during exercise testing in healthy premenopausal women. [2005.06]
[Metoprolol and atenolol in mild-to-moderate chronic heart failure: comparative study] [2005.05]
The rationale and design of the Glycemic Effects in Diabetes Mellitus Carvedilol-Metoprolol Comparison in Hypertensives (GEMINI) trial. [2005.03]
Association between adherence measurements of metoprolol and health care utilization in older patients with heart failure. [2005.03]
Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET. [2005.02]
What resting heart rate should one aim for when treating patients with heart failure with a beta-blocker? Experiences from the Metoprolol Controlled Release/Extended Release Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF). [2005.01.18]
Efficacy, safety and tolerability of metoprolol CR/XL in patients with diabetes and chronic heart failure: experiences from MERIT-HF. [2005.01]
Carvedilol versus metoprolol in the acute phase of myocardial infarction:. [2005.01]
Pharmacokinetic drug interactions of gefitinib with rifampicin, itraconazole and metoprolol. [2005]
Consistency of the beneficial effect of metoprolol succinate extended release across a wide range dose of angiotensin-converting enzyme inhibitors and digitalis. [2004.12]
Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial. [2004.11.10]
Efficacy, safety and tolerability of beta-adrenergic blockade with metoprolol CR/XL in elderly patients with heart failure. [2004.08]
Comprehensive adrenergic receptor blockade with carvedilol is superior to beta-1-selective blockade with metoprolol in patients with heart failure: COMET. [2004.07]
Carvedilol but not metoprolol reduces beta-adrenergic responsiveness after complete elimination from plasma in vivo. [2004.06.29]
Effects of moxonidine vs. metoprolol on blood pressure and metabolic control in hypertensive subjects with type 2 diabetes. [2004.06]
Effects of metoprolol on QT interval and QT dispersion in Type 1 diabetic patients with abnormal albuminuria. [2004.06]
Metoprolol and coronary artery bypass grafting surgery: does intraoperative metoprolol attenuate acute beta-adrenergic receptor desensitization during cardiac surgery? [2004.05]
Metoprolol CR/XL improves systolic and diastolic left ventricular function in patients with chronic heart failure. [2004.04]
The Diabetic Postoperative Mortality and Morbidity (DIPOM) trial: rationale and design of a multicenter, randomized, placebo-controlled, clinical trial of metoprolol for patients with diabetes mellitus who are undergoing major noncardiac surgery. [2004.04]
Effect of low-dose metoprolol in combination with sibutramine therapy in normotensive obese patients: a randomized controlled study. [2004.03]
A description of the clinical characteristics at baseline of patients recruited into the Carvedilol or Metoprolol European Trial (COMET). [2004.03]
Pharmacokinetic and pharmacodynamic interactions between metoprolol and dronedarone in extensive and poor CYP2D6 metabolizers healthy subjects. [2004.02]
Effectiveness of metoprolol in preventing atrial fibrillation and flutter in the postoperative period of coronary artery bypass graft surgery. [2004.01]
Reduction (TELMAR) as assessed by magnetic resonance imaging in patients with mild-to-moderate hypertension--a prospective, randomised, double-blind comparison of telmisartan with metoprolol over a period of six months rationale and study design. [2003.12]
Metoprolol CR/XL in postmyocardial infarction patients with chronic heart failure: experiences from MERIT-HF. [2003.10]
Increased exercise ejection fraction and reversed remodeling after long-term treatment with metoprolol in congestive heart failure: a randomized, stratified, double-blind, placebo-controlled trial in mild to moderate heart failure due to ischemic or idiopathic dilated cardiomyopathy. [2003.10]
Comparative impact of enalapril, candesartan or metoprolol alone or in combination on ventricular remodelling in patients with congestive heart failure. [2003.10]
Effects of cold exposure on submaximal exercise performance and adrenergic activation in patients with congestive heart failure and the effects of beta-adrenergic blockade (carvedilol or metoprolol). [2003.09.01]
How should subgroup analyses affect clinical practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF). [2003.09]
Effects of spironolactone and metoprolol on QT dispersion in heart failure. [2003.09]
Comparative effects of carvedilol and metoprolol on regional vascular responses to adrenergic stimuli in normal subjects and patients with chronic heart failure. [2003.08.26]
Celecoxib inhibits metabolism of cytochrome P450 2D6 substrate metoprolol in humans. [2003.08]
Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial. [2003.07.05]
Pain on injection of propofol: comparison of metoprolol with lidocaine. [2003.06]
Different responses to dobutamine in the presence of carvedilol or metoprolol in patients with chronic heart failure. [2003.06]
Extended-release metoprolol succinate in chronic heart failure. [2003.05]
Double-blind, placebo-controlled, randomized trial of prophylactic metoprolol for reduction of hospital length of stay after heart surgery: the beta-Blocker Length Of Stay (BLOS) study. [2003.02]
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