Tobrex (Tobramycin Ophthalmic) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The most frequent adverse reactions to TOBREX Ophthalmic Solution are hypersensitivity and localized ocular toxicity, including lid itching and swelling, and conjunctival erythema. These reactions occur in less than three of 100 patients treated with TOBREX. Similar reactions may occur with the topical use of other aminoglycoside antibiotics. Other adverse reactions have not been reported from TOBREX (tobramycin ophthalmic solution) 0.3% therapy; however, if topical ocular tobramycin is administered concomitantly with systemic aminoglycoside antibiotics, care should be taken to monitor the total serum concentration.

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO TOBREX

Possible Tobrex side effects / adverse reactions in 75 year old female

Reported by a physician from France on 2007-02-12

Patient: 75 year old female

Reactions: Toxic Skin Eruption

Suspect drug(s):
Lucentis(ranibizumab) Pwder + Solvent, Injection Soln
    Dosage: 93 mg, intravitreal
    Indication: Macular Degeneration
    Start date: 2006-12-29

Tetracaine(tetracaine)
    Dosage: gtt, ophthalmic
    Indication: Drug USE FOR Unknown Indication

Tobrex
    Dosage: gtt, ophthalmic
    Indication: Drug USE FOR Unknown Indication

Oxybuprocaine(benoxinate Hydrochloride)
    Dosage: gtt, ophthalmic
    Indication: Drug USE FOR Unknown Indication

Iopidine
    Dosage: gtt, ophthalmic
    Indication: Drug USE FOR Unknown Indication

Betadine
    Indication: Drug USE FOR Unknown Indication

Sodium Hypochlorite(sodium Hypochlorite)
    Indication: Drug USE FOR Unknown Indication

Other drugs received by patient: Novonorm (Repaglinide); Lipanor (Ciprofibrate); Fosamax; Aceclofenac (Aceclofenac); Voltaren Emulgel (Diclofenac Diethylammonium Salt); Dafalgan (Acetaminophen); Lorazepam; Atenolol; Vastarel (Trimetazidine); Euphytose (Ballota, Caffeine, Crategus, Kola, Passion Flower, Valerian; DI-Antalvic (Acetaminophen, Propoxyphene Hydrochloride); Carteol (Carteolol Hydrochloride)

Possible Tobrex side effects / adverse reactions in 75 year old female

Reported by a physician from France on 2007-02-23

Patient: 75 year old female

Reactions: Rash Erythematous, Toxic Skin Eruption, Rash Pruritic

Suspect drug(s):
Lucentis
    Dosage: 93 mg, unk; intravitreal
    Indication: Macular Degeneration
    Start date: 2006-12-29

Tetracaome (Tetracaine)
    Dosage: unk gtt, unk, ophthalmic
    Indication: Drug USE FOR Unknown Indication

Tobrex
    Dosage: unk gtt, unk; ophthalmic
    Indication: Drug USE FOR Unknown Indication

Oxybuprocaine (Benoxinate Hydrochloride)
    Dosage: unk gtt, unk, ophthalmic
    Indication: Drug USE FOR Unknown Indication

Iopidine
    Dosage: unk gtt, unk, ophthalmic
    Indication: Drug USE FOR Unknown Indication

Betadine
    Indication: Drug USE FOR Unknown Indication

Sodium Hypochlorite (Sodium Hyprochlorite)
    Indication: Drug USE FOR Unknown Indication

Other drugs received by patient: Novonorm (Repaglinide); Lipanor (Ciprofibrate); Foramax (Alendronate Sodium); Aceclofenac (Aceclofenac); Voltaren Emulgel (Diclofenac Diethylammonium Salt); Dafalgan (Acetaminophen); Lorazepam; Atenolol; Vastarel (Trimetazidine); Euphytose (Ballota, Caffeine, Crategus, Kola, Passion Flower, Valerian; DI-Antalvic (Acetaminophen, Propoxyphene Hydrochloride); Carteol (Carteolol Hydrochloride)