ADVERSE REACTIONS
As with other penicillins, the following adverse reactions may occur:
Hypersensitivity Reactions
Skin rash, pruritus, urticaria, arthralgia, myalgia, drug fever, chills, chest discomfort, erythema multiforme, toxic epidermal necrolysis, Stevens-Johnson syndrome, and anaphylactic reactions.
Central Nervous System
Headache, giddiness, neuromuscular hyperirritability, or convulsive seizures.
Gastrointestinal Disturbances
Disturbances of taste and smell, stomatitis, flatulence, nausea, vomiting and diarrhea, epigastric pain, and pseudomembranous colitis have been reported. Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment. (See WARNINGS.)
Hemic and Lymphatic Systems
Thrombocytopenia, leukopenia, neutropenia, eosinophilia, reduction of hemoglobin or hematocrit, and prolongation of prothrombin time and bleeding time.
Abnormalities of Hepatic Function Tests
Elevation of serum aspartate aminotransferase (SGOT), serum alanine aminotransferase (SGPT), serum alkaline phosphatase, serum LDH, serum bilirubin. There have been reports of transient hepatitis and cholestatic jaundice—as with some other penicillins and some cephalosporins.
Renal and Urinary Effects
Elevation of serum creatinine and/or BUN, hypernatremia, reduction in serum potassium and uric acid. Rare reports of hemorrhagic cystitis.
Local Reactions
Pain, burning, swelling, and induration at the injection site and thrombophlebitis with intravenous administration.
Available safety data for pediatric patients treated with TIMENTIN demonstrate a similar adverse event profile to that observed in adult patients.
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REPORTS OF SUSPECTED TIMENTIN SIDE EFFECTS / ADVERSE REACTIONS
Below is a sample of reports where side effects / adverse reactions may be related to Timentin. The information is not vetted and should not be considered as verified clinical evidence.
Possible Timentin side effects / adverse reactions in 90 year old female
Reported by a physician from Greece on 2011-11-02
Patient: 90 year old female
Reactions: Dyspnoea, Cardiac Murmur, Angioedema, Rales, Otitis Externa, Atrial Fibrillation, Erythema, Viith Nerve Paralysis, Hypoacusis, C-Reactive Protein Increased, Conjunctival Hyperaemia, Oedema Peripheral, Blood Immunoglobulin E Increased, Renal Failure Acute, Herpes Virus Infection
Adverse event resulted in: hospitalization
Suspect drug(s):
Netilmicin Sulfate
Timentin
Possible Timentin side effects / adverse reactions in 50 year old male
Reported by a physician from United States on 2012-04-16
Patient: 50 year old male
Reactions: Toxic Epidermal Necrolysis, Septic Shock
Adverse event resulted in: death
Suspect drug(s):
Timentin
Indication: Cellulitis
Vancomycin Hydrochloride
Indication: Cellulitis
Possible Timentin side effects / adverse reactions in 85 year old female
Reported by a physician from Greece on 2012-05-25
Patient: 85 year old female
Reactions: Depressed Level of Consciousness, Hypokalaemia
Suspect drug(s):
Timentin
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