Media Articles Related to Tilade (Nedocromil Inhalation)
Common Asthma Meds May Raise Sleep Apnea Risk, Study Says
Source: MedicineNet Asthma: Over The Counter Treatment Specialty [2014.02.28]
Title: Common Asthma Meds May Raise Sleep Apnea Risk, Study Says
Category: Health News
Created: 2/28/2014 9:35:00 AM
Last Editorial Review: 2/28/2014 12:00:00 AM
FDA Panels: Primatene HFA Inhaler Not Recommended for Asthma
Source: Medscape Family Medicine Headlines [2014.02.25]
Panel members took some issue with over-the-counter availability as a replacement for appropriate medical care.
Medscape Medical News
Genetic profiles obtained from nasal passages could guide individualized asthma therapy and research
Source: Respiratory / Asthma News From Medical News Today [2014.02.21]
It has become increasingly clear in recent years that asthma comes in several variations, with different causes, different pathologies and different responses to therapy. These subtypes of asthma can be identified by knowing which genes are expressed at higher and lower levels in patients' airways.
Source: MedicineNet Allergy Treatment Begins At Home Specialty [2014.02.19]
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 2/19/2014 5:03:40 PM
Pregnant women taking risks with asthma medication
Source: Respiratory / Asthma News From Medical News Today [2014.02.17]
Pregnant women are exposing themselves and their unborn babies to unnecessary risk by stopping their asthma medication without consulting their doctor.Pregnant women suffering from asthma could better manage the condition if additional integrated care involving education and monitoring was introduced in Australian hospitals, a new study has found.
Published Studies Related to Tilade (Nedocromil Inhalation)
Long-term budesonide or nedocromil treatment, once discontinued, does not alter the course of mild to moderate asthma in children and adolescents. [2009.05]
OBJECTIVES: To determine whether long-term, continuous use of inhaled anti-inflammatory medications affects asthma outcomes in children with mild to moderate asthma after use is discontinued... CONCLUSIONS: Clinically meaningful improvements in the control of asthma and in airway responsiveness achieved during continuous treatment with inhaled corticosteroids do not persist after continuous treatment is discontinued.
AMP challenge induces a decrease in FE(NO) in asthmatic subjects modulated by nedocromil. [2006.12]
BACKGROUND: Allergen challenge results in an immediate reduction in exhaled nitric oxide (FE(NO)) followed by a long-term increase. To study mast cell activation in relation to nitric oxide (NO), the study investigated the effect of inhaled adenosine monophosphate (AMP) as a mast cell activator and mast cell stabilizer - nedocromil sodium - on FE(NO). The NO synthase (NOS) iso-enzyme involved was studied by the NOS inhibitor aminoguanidine... CONCLUSIONS: The AMP challenge caused a reduction in FE(NO) as a result of prior treatment with nedocromil. Aminoguanidine abolished the nedocromil-induced protection on the late reduction in FE(NO), but not on AMP PC(20). Inducible NOS was implicated in the late FE(NO) decrease after the AMP challenge.
Efficacy and safety of mometasone furoate vs nedocromil sodium as prophylactic treatment for moderate/severe seasonal allergic rhinitis. [2006.05]
BACKGROUND: The preventive use of medications has been proposed to be effective in the treatment of seasonal rhinitis. OBJECTIVE: To evaluate the efficacy and safety of mometasone furoate and nedocromil sodium nasal sprays as prophylactic treatment for moderate to severe seasonal allergic rhinitis (SAR). PATIENTS: Sixty-one patients were recruited from 3 referral allergy centers. Inclusion criteria were history of SAR for 2 years or longer, sensitization to relevant local pollen (grasses, Parietaria, and olive), and age older than 12 years... CONCLUSIONS: Prophylactic administration of mometasone furoate before the pollen season is safe and may lead to improved control of SAR compared with the use of nedocromil sodium.
Dissociation in the effect of nedocromil on mannitol-induced cough or bronchoconstriction in asthmatic subjects. [2005.09]
CONCLUSIONS: Nedocromil strongly attenuates mannitol-induced bronchoconstriction but has a negligible effect on mannitol-provoked cough. Therefore, these responses seem to have different pathways in asthma. Recording of both provoked coughs and induced bronchoconstriction during mannitol challenge may provide supplementary information about a patient's disease.
Comparative effect of triamcinolone, nedocromil and montelukast on asthma control in children: A randomized pragmatic study. [2004.08]
Asthma severity can be judged by measurements of symptoms, lung function, and medication requirements. The objective was to compare the effect of a 4-wk monotherapy with low-dose triamcinolone, montelukast and nedocromil on asthma control, lung function, eosinophil blood count, and bronchial hyper-reactivity in children with mild to moderate asthma allergic to dust mite...
Clinical Trials Related to Tilade (Nedocromil Inhalation)
Early Airway Response to Allergen in Asthmatics (0000-176) [Recruiting]
This study will assess the Early Airway Response (EAR) associated change in forced
expiratory volume in one second (FEV1) and plasma 9a-11ß-PGF2 ('9P') after single dose
pretreatment of nedocromil, montelukast, and mometasone.