DESCRIPTION
Thiothixene is a thioxanthene derivative. Specifically, it is the cis isomer of N,N -dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide. It may be represented by the following structural formula:
The thioxanthenes differ from the phenothiazines by the replacement of nitrogen in the central ring with a carbon-linked side chain fixed in space in a rigid structural configuration. An N,N-dimethyl sulfonamide functional group is bonded to the thioxanthene nucleus.
Each capsule contains 1 mg, 2 mg, 5 mg or 10 mg of thiothixene, USP and the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, powdered cellulose, pregelatinized starch and sodium lauryl sulfate. In addition, each of the empty gelatin capsules contains gelatin and titanium dioxide and the following colorant agents:
1 mg - FD&C Blue No. 1, D&C Red No. 28, FD&C Red No. 40, FD&C Yellow No. 6
2 mg - FD&C Blue No. 1, FD&C Red No. 40, FD&C Yellow No. 6, D&C Yellow No. 10
5 mg - FD&C Blue No. 1, FD&C Red No. 40, FD&C Yellow No. 6
10 mg - FD&C Blue No. 1, FD&C Red No. 40, FD&C Yellow No. 6
The imprinting ink contains the following: black iron oxide, D&C Yellow No. 10 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake, FD&C Blue No. 2 Aluminum Lake, FD&C Red No. 40 Aluminum Lake, propylene glycol and shellac glaze.
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