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Tetracycline (Tetracycline Hydrochloride) - Side Effects and Adverse Reactions

 
 



Adverse Reactions:

Gastrointestinal:

Anorexia, nausea, epigastric distress, vomiting, diarrhea, glossitis, black hairy tongue, dysphagia, enterocolitis, and inflammatory lesions (with monilial overgrowth) in the anogenital region.

Rare instances of esophagitis and esophageal ulceration have been reported in patients receiving particularly the capsule and also the tablet forms of tetracyclines. Most of the patients were reported to have taken medication immediately before going to bed (see DOSAGE AND ADMINISTRATION section).

Teeth:

Permanent discoloration of teeth may be caused during tooth development. Enamel hypoplasia has also been reported (see WARNINGS   ).

Skin:

Maculopapular and erythrematous rashes. Exfoliative dermatitis has been reported but is uncommon. Onycholysis and discoloration of the nails have been reported rarely. Photosensitivity is discussed in WARNINGS   .

Renal Toxicity:

Rise in BUN has been reported and is apparently dose related.

Liver:

Hepatotoxicity and liver failure have been observed in patients receiving large doses of tetracycline and tetracyclinetreated patients with renal impairment.

Hypersensitivity Reactions:

Urticaria, angioneurotic edema, anaphylaxis, anaphylactoid purpura, pericarditis, exacerbation of systemic lupus erythematosus, and serum sickness-like reactions, as fever, rash, and arthralgia.

Blood:

Hemolytic anemia, thrombocytopenia, thrombocytopenic purpura, neutropenia and eosinophilia have been reported.

Other:

Bulging fontanels in infants and intracranial pressure in adults (see PRECAUTIONS General).

When given over prolonged periods, tetracyclines have been reported to produce brown-black microscopic discoloration of thyroid glands. No abnormalities of thyroid function studies are known to occur.



REPORTS OF SUSPECTED TETRACYCLINE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Tetracycline. The information is not vetted and should not be considered as verified clinical evidence.

Possible Tetracycline side effects / adverse reactions in 83 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-26

Patient: 83 year old female

Reactions: Toxic Anterior Segment Syndrome

Suspect drug(s):
NEO-Synephrine 2.5 % EYE Drops (Not Specified)
    Dosage: (ophthalmic)
    Indication: Preoperative Care
    Start date: 2011-10-05
    End date: 2011-10-05

BSS
    Dosage: (intraocular)
    Indication: Eye Irrigation
    Start date: 2011-10-05
    End date: 2011-10-05

Tetracycline
    Dosage: (ophthalmic)
    Indication: Preoperative Care
    Start date: 2011-10-05
    End date: 2011-10-05

Vigamox
    Dosage: (ophthalmic)
    Indication: Preoperative Care
    Start date: 2011-10-05
    End date: 2011-10-05

Nevanac
    Dosage: (ophthalmic)
    Indication: Preoperative Care
    Start date: 2011-10-05
    End date: 2011-10-05

Mydriacyl
    Dosage: (ophthalmic)
    Indication: Preoperative Care
    Start date: 2011-10-05
    End date: 2011-10-05



Possible Tetracycline side effects / adverse reactions in 14 year old female

Reported by a health professional (non-physician/pharmacist) from Singapore on 2011-10-28

Patient: 14 year old female

Reactions: Periorbital Oedema

Suspect drug(s):
Acetylsalicylic Acid SRT

Bactrim

Voltaren

Mefenamic Acid

Naproxen Sodium

Tetracycline



Possible Tetracycline side effects / adverse reactions in 14 year old female

Reported by a health professional (non-physician/pharmacist) from Singapore on 2011-10-28

Patient: 14 year old female

Reactions: Periorbital Oedema

Suspect drug(s):
Tetracycline

Acetylsalicylic Acid SRT

Mefenamic Acid

Bactrim

Naproxen Sodium

Voltaren



See index of all Tetracycline side effect reports >>

Drug label data at the top of this Page last updated: 2006-02-22

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