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Tessalon (Benzonatate) - Summary

 
 



TESSALON SUMMARY

TESSALON, a non-narcotic oral antitussive agent.

TESSALON is indicated for the symptomatic relief of cough.


See all Tessalon indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Tessalon (Benzonatate)

Study finds e-cigarette use linked to cough reflex sensitivity
Source: Respiratory / Asthma News From Medical News Today [2015.08.21]
The popularity of electronic cigarettes has steadily increased worldwide, but little is known about their effects on health.

Cough
Source: MedicineNet Alpha 1 Antitrypsin Deficiency Specialty [2015.06.16]
Title: Cough
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 6/16/2015 12:00:00 AM

Is a Cough Contagious?
Source: MedicineNet Croup Specialty [2015.05.28]
Title: Is a Cough Contagious?
Category: Diseases and Conditions
Created: 5/28/2015 12:00:00 AM
Last Editorial Review: 5/28/2015 12:00:00 AM

Preteen Whooping Cough Vaccine Loses Strength Over Time, CDC Finds
Source: MedicineNet Immunizations Specialty [2015.05.04]
Title: Preteen Whooping Cough Vaccine Loses Strength Over Time, CDC Finds
Category: Health News
Created: 5/4/2015 12:00:00 AM
Last Editorial Review: 5/4/2015 12:00:00 AM

Children's Cough Causes and Treatments
Source: MedicineNet Croup Specialty [2015.01.22]
Title: Children's Cough Causes and Treatments
Category: Diseases and Conditions
Created: 11/19/2012 12:00:00 AM
Last Editorial Review: 1/22/2015 12:00:00 AM

more news >>

Published Studies Related to Tessalon (Benzonatate)

Cardiac arrest with residual blindness after overdose of Tessalon(R) (benzonatate) perles. [2011.08]
CONCLUSION: Ingestion of Tessalon(R), a seemingly innocuous and widely prescribed antitussive, may pose a risk to patients due to its potential for the rapid development of life-threatening adverse events and limited treatment options in the overdose setting. Rational prescribing and patient education is needed. Copyright (c) 2011 Elsevier Inc. All rights reserved.

Benzonatate Ingestion Reported to the National Poison Center Database System (NPDS). [2010.12]
Little has been published on benzonatate ingestion, with the few case reports suggesting significant risk of seizures after poisoning. A 7-year retrospective review of all single substance ingestion of benzonatate reported to the National Poison Center Database System (NPDS) from 2000 to 2006...

Inhibition of cough-reflex sensitivity by benzonatate and guaifenesin in acute viral cough. [2009.06]
Acute cough due to viral upper respiratory tract infection (URI) is the most common form of cough and accounts for tremendous expenditure on prescription and non-prescription cough products worldwide. However, few agents have been shown in properly conducted clinical trials to be effective for cough due to URI...

Inhibition of cough-reflex sensitivity by benzonatate and guaifenesin in acute viral cough. [2008.12.31]
Acute cough due to viral upper respiratory tract infection (URI) is the most common form of cough and accounts for tremendous expenditure on prescription and non-prescription cough products worldwide. However, few agents have been shown in properly conducted clinical trials to be effective for cough due to URI...

Benzonatate for opioid-resistant cough in advanced cancer. [1998.01]
Chronic cough is a distressing symptom experienced by approximately 37% of patients with advanced cancer. Palliation of chronic nonproductive cough should always first address the underlying cause but in some patients chronic, nonproductive cough persists and antitussive agents are required... We report three patients with an opioid-resistant cough who achieved symptomatic relief with the peripherally acting nonopioid drug benzonatate.

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Clinical Trials Related to Tessalon (Benzonatate)

Benzonatate Dose Tolerance Study [Completed]
This is a single-center, randomized, third party blind, placebo controlled, dose escalation study of benzonatate following single dose administration. The primary oobjective is to assess the safety and tolerability of increasing oral doses of benzonatate following single dose administration in healthy male and female subjects.

Evaluation of the Effect of Benzonatate on QT Intervals Following Single Dose Administration of Benzonatate to Healthy Volunteers [Completed]
The primary objective of this study is to determine the effects of benzonatate (200 mg and 800 mg) on the QT interval following single dose oral administration at each time point post-dose.

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Reports of Suspected Tessalon (Benzonatate) Side Effects

Malaise (9)Depression (9)Vomiting (9)Stress (9)Abdominal Pain (7)Headache (7)Fatigue (7)Cleft Palate (7)Cleft LIP (7)Cognitive Disorder (7)more >>


Page last updated: 2015-08-21

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