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Terazol (Terconazole Vaginal) - Drug Interactions, Contraindications, Overdosage, etc

 
 



DRUG INTERACTIONS

TERAZOL® (terconazole) Vaginal Cream 0.4% and TERAZOL® (terconazole) Vaginal Suppositories 80 mg:

The therapeutic effect of these products is not affected by oral contraceptive usage.

TERAZOL® (terconazole) Vaginal Cream 0.8%:

The levels of estradiol (E2) and progesterone did not differ significantly when 0.8% terconazole vaginal cream was administered to healthy female volunteers established on a low dose oral contraceptive.

OVERDOSAGE

Overdose of terconazole in humans has not been reported to date. In the rat, the oral LD 50 values were found to be 1741 and 849 mg/kg for the male and female, respectively. The oral LD 50 values for the male and female dog were ≅1280 and ≥640 mg/kg, respectively.

CONTRAINDICATIONS

Patients known to be hypersensitive to terconazole or to any of the components of the cream or suppositories.

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