ADVERSE REACTIONS
In human dermal safety studies, tazarotene 0.05% and 0.1% gels
did not induce allergic contact sensitization, phototoxicity or
photoallergy.
Psoriasis:
The most frequent adverse events reported with TAZORAC® Gel 0.05% and 0.1% were limited to the skin. Those occurring
in 10 to 30% of patients, in descending order, included pruritus,
burning/stinging, erythema, worsening of psoriasis, irritation, and skin pain.
Events occurring in 1 to 10% of patients included rash, desquamation, irritant
contact dermatitis, skin inflammation, fissuring, bleeding and dry skin.
Increases in “psoriasis worsening” and “sun-induced erythema” were noted in some
patients over the 4th to 12th months as compared to the first three months of a
1 year study. In general, the incidence of adverse events with TAZORAC® Gel 0.05% was 2 to 5% lower than that seen with TAZORAC® Gel 0.1%.
Acne:
The most frequent adverse events reported with TAZORAC® Gel 0.1% in the treatment of acne occurring in 10 to 30% of
patients, in descending order, included desquamation, burning/stinging, dry
skin, erythema and pruritus. Events occurring in 1 to 10% of patients included
irritation, skin pain, fissuring, localized edema and skin discoloration.
|
REPORTS OF SUSPECTED TAZORAC SIDE EFFECTS / ADVERSE REACTIONS
Below is a sample of reports where side effects / adverse reactions may be related to Tazorac. The information is not vetted and should not be considered as verified clinical evidence.
Possible Tazorac side effects / adverse reactions in male
Reported by a consumer/non-health professional from United States on 2011-10-04
Patient: male weighing 3.2 kg (7.0 pounds)
Reactions: Maternal Exposure During Pregnancy, Pregnancy
Adverse event resulted in: life threatening event, hospitalization, disablity
Suspect drug(s):
Tazorac
Possible Tazorac side effects / adverse reactions in 54 year old male
Reported by a physician from United States on 2012-02-15
Patient: 54 year old male weighing 142.7 kg (313.9 pounds)
Reactions: Prostate Cancer
Suspect drug(s):
Tazorac
Other drugs received by patient: Neurontin
Possible Tazorac side effects / adverse reactions in 42 year old female
Reported by a consumer/non-health professional from United States on 2012-02-17
Patient: 42 year old female
Reactions: Application Site Discolouration
Suspect drug(s):
Tazorac
|