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Tapazole (Methimazole) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Major adverse reactions (which occur with much less frequency than the minor adverse reactions) include inhibition of myelopoieses (agranulocytosis, granulocytopenia, thrombocytopenia, and aplastic anemia), drug fever, a lupus-like syndrome, insulin autoimmune syndrome (which can result in hypoglycemic coma), hepatitis (jaundice may persist for several weeks after discontinuation of the drug), periarteritis, and hypoprothrombinemia. Nephritis occurs very rarely.

Minor adverse reactions include skin rash, urticaria, nausea, vomiting, epigastric distress, arthralgia, paresthesia, loss of taste, abnormal loss of hair, myalgia, headache, pruritus, drowsiness, neuritis, edema, vertigo, skin pigmentation, jaundice, sialadenopathy, and lymphadenopathy.

 



REPORTS OF SUSPECTED TAPAZOLE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Tapazole. The information is not vetted and should not be considered as verified clinical evidence.

Possible Tapazole side effects / adverse reactions in 72 year old male

Reported by a physician from United States on 2011-10-11

Patient: 72 year old male

Reactions: White Blood Cell Count Decreased, Intussusception, Vomiting, Nausea, Colonic Obstruction, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Suspect drug(s):
Leukine
    Dosage: 3500 mcg, total
    Indication: Malignant Melanoma
    Start date: 2011-05-31
    End date: 2011-09-06

Tapazole

Ipilimumab
    Dosage: 2961.6 mg, total
    Indication: Malignant Melanoma
    Start date: 2011-05-31
    End date: 2011-08-02

Other drugs received by patient: Venofer



Possible Tapazole side effects / adverse reactions in 72 year old male

Reported by a individual with unspecified qualification from United States on 2011-10-11

Patient: 72 year old male

Reactions: White Blood Cell Count Decreased, Intussusception, Vomiting, Nausea, Pleural Effusion, Colonic Obstruction, Neutropenia, Neutrophil Count Decreased, Metastases TO Gastrointestinal Tract, Metastases TO Lung

Adverse event resulted in: hospitalization

Suspect drug(s):
Ipilimumab
    Dosage: 2961.6 mg, total
    Indication: Malignant Melanoma
    Start date: 2011-05-31
    End date: 2011-08-02

Leukine
    Dosage: 3500 mcg, total
    Indication: Malignant Melanoma
    Start date: 2011-05-31
    End date: 2011-09-06

Tapazole

Other drugs received by patient: Venofer



Possible Tapazole side effects / adverse reactions in 86 year old female

Reported by a physician from Italy on 2011-10-20

Patient: 86 year old female

Reactions: Weight Decreased, Immunoglobulins Abnormal, Dyspepsia, Alanine Aminotransferase Increased, Decreased Appetite

Adverse event resulted in: hospitalization

Suspect drug(s):
Nimesulide
    Dosage: 100 mg, as needed
    Administration route: Oral
    Indication: Osteoarthritis
    Start date: 2009-01-01
    End date: 2011-08-16

Atorvastatin Calcium
    Dosage: 20 mg, daily
    Administration route: Oral
    Indication: Coronary Artery Disease
    Start date: 2009-01-01
    End date: 2011-08-29

Tapazole
    Dosage: 5 mg, weekly
    Administration route: Oral
    Indication: Goitre
    Start date: 2009-01-01
    End date: 2011-09-06



See index of all Tapazole side effect reports >>

Drug label data at the top of this Page last updated: 2013-03-13

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