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Talwin (Pentazocine Lactate) - Side Effects and Adverse Reactions

 
 



Adverse Reactions

The most commonly occurring reactions are: nausea, dizziness or lightheadedness, vomiting, euphoria.
Dermatologic Reactions: Soft tissue induration, nodules, and cutaneous depression can occur at injection sites. Ulceration (sloughing) and severe sclerosis of the skin and subcutaneous tissues (and, rarely, underlying muscle) have been reported after multiple doses. Other reported dermatologic reactions include diaphoresis, sting on injection, flushed skin including plethora, dermatitis including pruritus. Infrequently occurring reactions are—respiratory: respiratory depression, dyspnea, transient apnea in a small number of newborn infants whose mothers received TALWIN during labor; cardiovascular: circulatory depression, shock, hypertension; CNS effects: dizziness, lightheadedness, hallucinations, sedation, euphoria, headache, confusion, disorientation; infrequently weakness, disturbed dreams, insomnia, syncope, visual blurring and focusing difficulty, depression; and rarely tremor, irritability, excitement, tinnitus;
gastrointestinal: constipation, dry mouth; other: urinary retention, headache, paresthesia, alterations in rate or strength of uterine contractions during labor. Rarely reported reactions include—neuromuscular and psychiatric: muscle tremor, insomnia, disorientation, hallucinations; gastrointestinal: taste alteration, diarrhea and cramps; ophthalmic: blurred vision, nystagmus, diplopia, miosis; hematologic: depression of white blood cells (especially granulocytes), which is usually reversible, moderate transient eosinophilia; other: tachycardia, weakness or faintness, chills; allergic reactions including edema of the face, toxic epidermal necrolysis. (See Acute CNS Manifestations and Drug Dependence under WARNINGS.)



REPORTS OF SUSPECTED TALWIN SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Talwin. The information is not vetted and should not be considered as verified clinical evidence.

Possible Talwin side effects / adverse reactions in 53 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-15

Patient: 53 year old male

Reactions: Jaundice, Hepatic Function Abnormal, Pain, Coagulopathy, Headache, Pyrexia, Transaminases Increased, Haemangioma of Liver, Malaise, Bacterial Test Positive, Cough, Decreased Appetite, Back Pain, Chromaturia, Nitrite Urine Present, Encephalopathy, White Blood Cells Urine Positive, Diarrhoea, Drug-Induced Liver Injury, Dysuria

Adverse event resulted in: hospitalization

Suspect drug(s):
Ampyra
    Indication: Multiple Sclerosis

Dalfampridine ER 10mg (Dalfampridine ER) Tablet
    Dosage: bid
    Indication: Multiple Sclerosis
    Start date: 2012-03-05
    End date: 2012-04-12

Talwin
    Indication: Back Pain
    Start date: 2012-05-10

Other drugs received by patient: Nuvigil; SAW Palmetto /00833501/ (Serenoa Repens); Tysabri; Advil /00044201/ (Mefenamic Acid); Effexor; Cyclobenzaprine



Possible Talwin side effects / adverse reactions in 53 year old male

Reported by a physician from United States on 2012-06-27

Patient: 53 year old male

Reactions: Transaminases Increased

Adverse event resulted in: hospitalization

Suspect drug(s):
ALL Other Therapeutic Products
    Indication: Multiple Sclerosis

Blinded Therapy
    Indication: Multiple Sclerosis
    Start date: 2012-03-05
    End date: 2012-04-12

Talwin
    Indication: Back Pain
    Start date: 2012-05-10

Other drugs received by patient: SAW Palmetto; Ibuprofen (Advil); ALL Other Therapeutic Products; Cyclobenzaprine; Immunosuppressive Agents; Effexor



Possible Talwin side effects / adverse reactions in 53 year old male

Reported by a physician from United States on 2012-07-26

Patient: 53 year old male

Reactions: Transaminases Increased

Adverse event resulted in: hospitalization

Suspect drug(s):
ALL Other Therapeutic Products
    Indication: Multiple Sclerosis

Blinded Therapy
    Indication: Multiple Sclerosis
    Start date: 2012-03-05
    End date: 2012-04-12

Talwin
    Indication: Back Pain
    Start date: 2012-05-10

Other drugs received by patient: Advil; Effexor; SAW Palmetto; Immunosuppressive Agents; Cyclobenazprine; ALL Other Therapeutic Products



See index of all Talwin side effect reports >>

Drug label data at the top of this Page last updated: 2012-02-17

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