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Synera (Lidocaine / Tetracaine Topical) - Summary

 


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SYNERA SUMMARY

SyneraTM
(lidocaine 70 mg and tetracaine 70 mg) topical patch

Synera™ consists of a thin, uniform layer of a local anesthetic formulation with an integrated, oxygen-activated heating component that is intended to enhance the delivery of the local anesthetic. The drug formulation is an emulsion in which the oil phase is a eutectic mixture of lidocaine 70 mg and tetracaine 70 mg. The eutectic mixture has a melting point below room temperature and therefore exists as a liquid oil rather than as crystals. The surface area of the entire Synera patch is approximately 50 cm2, 10 cm2 of which is active.

Synera™ is indicated for use on intact skin to provide local dermal analgesia for superficial venous access and superficial dermatological procedures such as excision, electrodessication and shave biopsy of skin lesions (see CLINICAL STUDIES section).


See all Synera indications & dosage >>

SYNERA NEWS HIGHLIGHTS

Media Articles Related to Synera (Lidocaine / Tetracaine Topical)

Spinal Anesthesia Doesn't Cause Restless Leg Syndrome
Source: MedicineNet Sleep Specialty [2008.11.20]

Cooling The Brain Prevents Cell Death In Young Mice Exposed To Anesthesia
Source: Pain / Anesthetics News From Medical News Today [2008.11.18]

Possible Risk Developmental Problems Following General Anesthesia For Hernia Surgery In Children
Source: Pain / Anesthetics News From Medical News Today [2008.11.10]

Grant To Continue Neuropathy Research Awarded To McGill Professor
Source: Pain / Anesthetics News From Medical News Today [2008.11.12]

Award To HJF Nursing Specialist Recognizes Excellence In Caregiving
Source: Caregivers / Homecare News From Medical News Today [2008.11.09]

more >>

Published Studies Related to Synera (Lidocaine / Tetracaine Topical)

Warm lidocaine/tetracaine patch versus placebo before pediatric intravenous cannulation: a randomized controlled trial. [2008.07]

Brief Report: A randomized controlled trial of SyneraTM versus lidocaine for epidural needle insertion in labouring parturients: [Compte-rendu court : Une etude randomisee controlee du SyneraTM vs lidocaine dans l'insertion de l'aiguille peridurale chez les parturientes en travail]. [2008.03]

Randomized, double-blind, placebo-controlled study evaluating the lidocaine/tetracaine patch for induction of local anesthesia prior to minor dermatologic procedures in geriatric patients. [2005.03]

Self-warming lidocaine/tetracaine patch effectively and safely induces local anesthesia during minor dermatologic procedures. [2005.02]

Use of the Synera patch for local anesthesia before vascular access procedures: a randomized, double-blind, placebo-controlled study. [2007.09]

more >>

Clinical Trials Related to Synera (Lidocaine / Tetracaine Topical)

Syneraâ„¢ for Epidural Needle Insertion [Completed]

Pharmacokinetic Study of Syneraâ„¢ in Neonates and Infants [Recruiting]

The Efficacy of EMLA Cream vs. Synera Patch for Pain Reduction During Venipuncture in Children [Recruiting]

Evaluate Efficacy, Safety & Subject Satisfaction of Pain Management With Pliaglis® Cream for Dermal Filler Injections [Recruiting]

Lidocaine and Tetracaine Cream to Treat Postherpetic Neuralgia (PHN) [Recruiting]

more >>

Page last updated: 2008-11-20

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