Surmontil (Trimipramine Maleate) - Summary

SURMONTIL SUMMARY

Surmontil is an antidepressant with an anxiety-reducing sedative component to its action.

Surmontil is indicated for the relief of symptoms of depression. Endogenous depression is more likely to be alleviated than other depressive states. In studies with neurotic outpatients, the drug appeared to be equivalent to amitriptyline in the less-depressed patients but somewhat less effective than amitriptyline in the more severely depressed patients. In hospitalized depressed patients, trimipramine and imipramine were equally effective in relieving depression.

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SURMONTIL NEWS HIGHLIGHTS

Media Articles Related to Surmontil (Trimipramine)

Depression linked to poorer diabetes control (Reuters)
Source: Y! Health Depression News [2008.11.19]

Depression Screening May Not Benefit Heart Disease Patients
Source: Depression News From Medical News Today [2008.11.17]

AMPAKINE(R) Compounds May Protect From Drug-induced Respiratory Depression While Still Allowing The Sedative Or Analgesic To Continue Working
Source: Respiratory / Asthma News From Medical News Today [2008.11.16]

Greater Risk Of Death For African-Americans With Depression And Heart Attack
Source: Depression News From Medical News Today [2008.11.13]

Heart Association Call For Routine Screening Of Heart Patients For Depression Is Premature, Johns Hopkins Expert Says
Source: Depression News From Medical News Today [2008.11.12]

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Published Studies Related to Surmontil (Trimipramine)

Fluoxetine versus trimipramine in the treatment of depression in geriatric patients. [2005.01]

Antipsychotic efficacy of the antidepressant trimipramine: a randomized, double-blind comparison with the phenothiazine perazine. [2003.03]

Differential effects of trimipramine and fluoxetine on sleep in geriatric depression. [2001.03]

Trimipramine and imipramine exert different effects on the sleep EEG and on nocturnal hormone secretion during treatment of major depression. [1996]

Treatment of primary insomnia with trimipramine: an alternative to benzodiazepine hypnotics? [1994]

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Clinical Trials Related to Surmontil (Trimipramine)

Treatment-Resistant Depression, Hippocampus Atrophy and Serotonin Genetic Polymorphism [Recruiting]

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