DRUG INTERACTIONS Drug Interactions
PENICILLIN - Since bacteriostatic drugs like tetracycline may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin.
ANTICOAGULANTS - Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage.
ANTACIDS AND IRON CONTAINING PRODUCTS - Absorption of tetracycline is impaired by antacids containing aluminum, calcium, or magnesium, and iron containing preparations.
ORAL CONTRACEPTIVES - Concurrent use of tetracycline may render oral contraceptives less effective.
METHOXYFLURANE - The concurrent use of tetracycline and methoxyflurane has been reported to result in fatal renal toxicity.
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