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Sulfadiazine (Sulfadiazine) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Blood Dyscrasias

Agranulocytosis, aplastic anemia, thrombocytopenia, leukopenia, hemolytic anemia, purpura, hypoprothrombinemia and methemoglobinemia.

Allergic Reactions

Erythema multiforme (Stevens-Johnson syndrome), generalized skin eruptions, epidermal necrolysis, urticaria, serum sickness, pruritus, exfoliative dermatitis, anaphylactoid reactions, periorbital edema, conjunctival and scleral injection, photosensitization, arthralgia, allergic myocarditis, drug fever and chills.

Gastrointestinal Reactions

Nausea, emesis, abdominal pains, hepatitis, diarrhea, anorexia, pancreatitis and stomatitis.

C.N.S. Reactions

Headache, peripheral neuritis, mental depression, convulsions, ataxia, hallucinations, tinnitus, vertigo and insomnia.

Renal

Crystalluria, stone formation, toxic nephrosis with oliguria and anuria; periarteritis nodosa and lupus erythematosus phenomenon have been noted.

Miscellaneous Reactions

The sulfonamides bear certain chemical similarities to some goitrogens, diuretics (acetazolamide and the thiazides) and oral hypoglycemic agents. Goiter production, diuresis, and hypoglycemia have occurred rarely in patients receiving sulfonamides. Cross-sensitivity may exist with these agents.



REPORTS OF SUSPECTED SULFADIAZINE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Sulfadiazine. The information is not vetted and should not be considered as verified clinical evidence.

Possible Sulfadiazine side effects / adverse reactions in 21 year old female

Reported by a consumer/non-health professional from Spain on 2011-10-12

Patient: 21 year old female

Reactions: Grand MAL Convulsion

Suspect drug(s):
Pred Fortea? Colirio EN Suspensi??n
    Dosage: unk
    Indication: Eye Infection Toxoplasmal
    Start date: 2011-08-31
    End date: 2011-09-16

Daraprim 25 MG Comprimidos , 30 Comprimidos
    Administration route: Oral
    Indication: Eye Infection Toxoplasmal
    Start date: 2011-08-31
    End date: 2011-09-16

Zamene 30 MG Comprimidos , 10 Comprimidos
    Administration route: Oral
    Indication: Eye Infection Toxoplasmal
    Start date: 2011-08-31
    End date: 2011-09-16

Sulfadiazine
    Administration route: Oral
    Indication: Eye Infection Toxoplasmal
    Start date: 2011-08-31
    End date: 2011-09-16



Possible Sulfadiazine side effects / adverse reactions in 20 year old female

Reported by a health professional (non-physician/pharmacist) from Iran (Islamic Republic OF) on 2011-11-18

Patient: 20 year old female

Reactions: Confusional State, Jaundice, Vomiting, Nausea, Nephropathy Toxic, Hepatotoxicity, Hepatorenal Syndrome, Hepatitis Fulminant, Decreased Appetite

Adverse event resulted in: hospitalization

Suspect drug(s):
Sulfadiazine

Other drugs received by patient: Pyrimethamine TAB; Prednisolone; Leucovorin Calcium



Possible Sulfadiazine side effects / adverse reactions in 82 year old male

Reported by a health professional (non-physician/pharmacist) from Spain on 2011-11-23

Patient: 82 year old male

Reactions: Abdominal Pain Lower, Urinary Tract Infection Bacterial, Haematuria, Proteinuria, Dysuria, Polyuria, Rectal Tenesmus, Renal Failure Acute

Suspect drug(s):
Sulfadiazine



See index of all Sulfadiazine side effect reports >>

Drug label data at the top of this Page last updated: 2013-06-25

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