SUFENTA SUMMARY
SUFENTA® (sufentanil citrate) is a potent opioid analgesic.
SUFENTA (sufentanil citrate) is indicated for intravenous administration in adults and pediatric patients:
as an analgesic adjunct in the maintenance of balanced general anesthesia in patients who are intubated and ventilated.
as a primary anesthetic agent for the induction and maintenance of anesthesia with 100% oxygen in patients undergoing major surgical procedures, in patients who are intubated and ventilated, such as cardiovascular surgery or neurosurgical procedures in the sitting position, to provide favorable myocardial and cerebral oxygen balance or when extended postoperative ventilation is anticipated.
SUFENTA (sufentanil citrate) is indicated for epidural administration as an analgesic combined with low dose bupivacaine, usually 12.5 mg per administration, during labor and vaginal delivery.
SEE DOSAGE AND ADMINISTRATION SECTION FOR MORE COMPLETE INFORMATION ON THE USE OF SUFENTA.
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NEWS HIGHLIGHTSMedia Articles Related to Sufenta (Sufentanil)
Concerns About Anesthesia's Impact On The Brain
Source: Pain / Anesthetics News From Medical News Today [2013.06.07]
As pediatric specialists become increasingly aware that surgical anesthesia may have lasting effects on the developing brains of young children, new research suggests the threat may also apply to adult brains...
Increasing Rates Of Emergency C-Section And Accompanying Emergency Anesthesia
Source: Pain / Anesthetics News From Medical News Today [2013.06.05]
There is an increasing need for safe emergency anaesthesia as cases of emergency Caesarean section (CS) continue to rise, said experts speaking at Euroanaesthesia, the annual congress of the European Society of Anaesthesiology (ESA)...
General Anesthesia Raises Dementia Risk Among Elderly Patients
Source: Pain / Anesthetics News From Medical News Today [2013.06.02]
Elderly patients who are exposed to general anesthesia have a 35% higher risk of developing dementia, researchers from INSERM and University of Bordeaux, France, reported at Euroanaesthesia, the annual congress of the European Society of Anaesthesiology (ESA)...
Faster Spinal Anesthesia For Cancer Patients At End Of Life
Source: Pain / Anesthetics News From Medical News Today [2013.05.29]
For patients with uncontrolled pain from terminal cancer, a new approach to calculating initial dosage may allow a quicker start of spinal analgesia - and less time in the hospital, according to a study in the June issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS)...
Patients With Sleep Apnea Undergoing Joint Replacement Have Improved Outcomes With Regional Anesthesia
Source: Pain / Anesthetics News From Medical News Today [2013.05.07]
Using regional anesthesia instead of general anesthesia in patients with sleep apnea undergoing total joint replacement decreases major complications by 17%, according to a study published online, ahead of print, in the journal Regional Anesthesia and Pain Medicine...
Published Studies Related to Sufenta (Sufentanil)
Addition of clonidine to a continuous patient-controlled epidural infusion of low-concentration levobupivacaine plus sufentanil in primiparous women during labour. [2011.09]
We studied the potentiation of analgesia for labour by the addition of clonidine to epidural low-concentration levobupivacaine with sufentanil in a randomised, double-blinded study. We enrolled primiparous women who were in spontaneous labour...
Comparison of intrathecal bupivacaine and ropivacaine with different doses of sufentanil. [2011.07]
BACKGROUND: Spinal bupivacaine produces a complete anaesthetic block of a longer duration than ropivacaine, which leads to a potentially increased risk of failure. A combination of sufentanil to ropivacaine may improve the block's reliability... CONCLUSION: Plain bupivacaine 10 mg has a longer recovery profile than the same dose of ropivacaine with or without sufentanil. (c) 2011 The Authors. Acta Anaesthesiologica Scandinavica (c) 2011 The Acta Anaesthesiologica Scandinavica Foundation.
A randomised comparison of intravenous remifentanil patient-controlled analgesia with epidural ropivacaine/sufentanil during labour. [2011.04]
BACKGROUND: The mu-opioid agonist remifentanil has a rapid onset and offset and a short half-life making it an attractive option for intravenous patient-controlled labour analgesia. We aimed to compare the efficacy of intravenous remifentanil patient-controlled analgesia with epidural ropivacaine/sufentanil during labour... CONCLUSIONS: In the 20 patients recruited to this study, pain relief in labour with epidural ropivacaine/sufentanil was more effective than with intravenous remifentanil patient-controlled analgesia. Copyright (c) 2010 Elsevier Ltd. All rights reserved.
Sedation with sufentanil and clonidine in patients undergoing heart catheterization. [2011.03]
BACKGROUND: Sedation for heart catheterization has been a cause for concern. Benzodiazepines, alpha-2 adrenergic agonists and opioids are used for this purpose. However, each drug has advantages and disadvantages. OBJECTIVE: To evaluate the efficacy of sufentanil and clonidine as sedative in patients undergoing heart catheterization, observing their impact on hemodynamic and respiratory parameters, the presence of side effects and satisfaction of the patient and interventional cardiologist with the examination... CONCLUSION: Sufentanil and clonidine were effective as sedative in patients undergoing heart catheterization.
Epidural ropivacaine and sufentanil and the perioperative stress response after a radical retropubic prostatectomy. [2011.03]
BACKGROUND: The effects of an epidural opioid and a local anesthetic on the perioperative stress responses have not been fully investigated in elderly patients undergoing cancer surgery. We hypothesized that the stress response after a radical retropubic prostatectomy (RRP) would be attenuated by epidural ropivacaine and sufentanil... CONCLUSION: Epidural ropivacaine blunted the perioperative stress responses in elderly patients undergoing a RRP. The combination of epidural ropivacaine and sufentanil was associated with the most pronounced attenuation of the stress response. ClinicalTrial.gov registration number: NCT01086956. (c) 2010 The Authors. Journal compilation (c) 2010 The Acta Anaesthesiologica Scandinavica Foundation.
Clinical Trials Related to Sufenta (Sufentanil)
Study of Cisatracurium and Sufentanil Consumption Using a Closed Loop Computer Control Infusion System [Recruiting]
A Dosing and Efficacy Study of Intra-nasal Sufentanil for Moderate to Severe Pain [Recruiting]
Pain Therapy After Elective Cardiac Surgery [Recruiting]
The purpose of this study is to determine generation of a target controlled infusion model
for the patient controlled analgesia with the strong analgesic, hydromorphone, after planned
open heart surgery, during which the strong analgesic, sufentanil, was used.
Efficacy and Safety Trial to Evaluate the Sufentanil NanoTab� PCA System/15 Mcg for Post-Operative Pain in Patients After Knee or Hip Replacement Surgery [Recruiting]
The Effect of Adding Sufentanyl to Bupivacaine in Transversus Abdominis Plane Block to Reduce the Narcotic Dosage and Pain After Cesarean Delivery [Recruiting]
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