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Starlix (Nateglinide) - Summary

 


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STARLIX SUMMARY

Starlix®

Starlix® (nateglinide)is an oral antidiabetic agent used in the management of Type 2 diabetes mellitus. Starlix, (-)-N-[(trans-4-isopropylcyclohexane)carbonyl]-D-phenylalanine, is structurally unrelated to the oral sulfonylurea insulin secretagogues.

Starlix® (nateglinide) is indicated as monotherapy to lower blood glucose in patients with Type 2 diabetes (non-insulin dependent diabetes mellitus, NIDDM) whose hyperglycemia cannot be adequately controlled by diet and physical exercise and who have not been chronically treated with other antidiabetic agents.

Starlix is also indicated for use in combination with metformin or a thiazolidinedione. In patients whose hyperglycemia is inadequately controlled with metformin or after a therapeutic response to a thiazolidinedione, Starlix may be added to, but not substituted for, those drugs.

Patients whose hyperglycemia is not adequately controlled with glyburide or other insulin secretagogues should not be switched to Starlix, nor should Starlix be added to their treatment regimen.


See all Starlix indications & dosage >>

STARLIX NEWS HIGHLIGHTS

Published Studies Related to Starlix (Nateglinide)

Improvement of glycaemic control by nateglinide decreases systolic blood pressure in drug-naive patients with type 2 diabetes. [2008.03]

Nateglinide reduces carotid intima-media thickening in type 2 diabetic patients under good glycemic control. [2007.11]

Improvement of insulin sensitivity and beta-cell function by nateglinide and repaglinide in type 2 diabetic patients - a randomized controlled double-blind and double-dummy multicentre clinical trial. [2007.07]

Nateglinide or gliclazide in combination with metformin for treatment of patients with type 2 diabetes mellitus inadequately controlled on maximum doses of metformin alone: 1-year trial results. [2007.07]

Insulin glargine in combination with nateglinide in people with Type 2 diabetes: a randomized placebo-controlled trial. [2007.04]

more >>

Clinical Trials Related to Starlix (Nateglinide)

Efficacy and Safety of Nateglinide Treatment in Renal Transplant Recipients [Completed]

A Pilot Study to Evaluate the Effects of Nateglinide Vs. Glibenclamide on Renal Hemodynamics and Albumin Excretion [Completed]

The Effects of Nateglinide and Acarbose on the Post-Prandial Glucose Control in Type 2 Diabetic Patients [Completed]

Long-Term Study of Nateglinide+Valsartan to Prevent or Delay Type II Diabetes Mellitus and Cardiovascular Complications [Active, not recruiting]

Safety and Efficacy of Nateglinide in Patients With Type 2 Diabetes Already Taking Insulin Glargine, Metformin and/or Pioglitazone or Rosiglitazone [Completed]

more >>

Page last updated: 2008-03-26

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