Contraindications:
Pregnancy Category X
(See boxed CONTRAINDICATIONS AND WARNINGS)
Soriatane is contraindicated in patients with severely impaired liver or kidney function and in patients with chronic abnormally elevated blood lipid values (see boxed Warnings: Hepatoxicity, Warnings: Lipids and Possible Cardiovascular Effects, and Precautions).
An increased risk of hepatitis has been reported to result from combined use of methotrexate and etretinate. Consequently, the combination of methotrexate with Soriatane is also contraindicated (see Precautions: Drug Interactions).
Since both Soriatane and tetracyclines can cause increased intracranial pressure, their combined use is contraindicated (see Warnings: Pseudotumor Cerebri).
Soriatane is contraindicated in cases of hypersensitivity to the preparation (acitretin or excipients) or to other retinoids.
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