Sonata (Zaleplon) - Summary

SONATA SUMMARY

Zaleplon is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class.

Sonata is indicated for the short-term treatment of insomnia. Sonata has been shown to decrease the time to sleep onset for up to 30 days in controlled clinical studies (see Clinical Trials under CLINICAL PHARMACOLOGY). It has not been shown to increase total sleep time or decrease the number of awakenings.

Hypnotics should generally be limited to 7 to 10 days of use, and reevaluation of the patient is recommended if they are to be taken for more than 2 to 3 weeks. Sonata should not be prescribed in quantities exceeding a 1-month supply (see WARNINGS).

SONATA NEWS HIGHLIGHTS

Media Articles Related to Sonata (Zaleplon)

Lowering Blood Pressure In Elderly Using Audio Relaxation Program
Source: Complementary Medicine / Alternative Medicine News From Medical News Today [2008.09.20]

Zaleplon
Source: MedicineNet zaleplon Specialty [2004.07.06]

Insomnia In Adolescence Linked To Depression And Substance Abuse During Adolescence And Young Adulthood
Source: Alcohol / Addiction / Illegal Drugs News From Medical News Today [2008.10.02]

Ten Tips to Avoid Insomnia and Get a Good Night's Sleep
Source: MedicineNet Sleep Aids And Stimulants Specialty [2008.06.05]

Persistent Insomnia Leads to Depression in Young Adults
Source: MedicineNet Sleep Aids And Stimulants Specialty [2008.04.03]

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Published Studies Related to Sonata (Zaleplon)

Zaleplon and zolpidem objectively alleviate sleep disturbances in mountaineers at a 3,613 meter altitude. [2007.11.01]

Sleep and residual sedation after administration of zaleplon, zolpidem, and placebo during experimental middle-of-the-night awakening. [2006.10.15]

High-performance liquid chromatography-atmospheric pressure chemical ionisation-mass spectrometry determination of zaleplon in human plasma. [2006.02.24]

Zaleplon (Sonata) oral sedation for outpatient third molar extraction surgery. [2005.01]

Sleep-inducing pharmaceuticals: a comparison of melatonin, zaleplon, zopiclone, and temazepam. [2004.06]

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Clinical Trials Related to Sonata (Zaleplon)

Pharmacokinetics of Staccato Zaleplon [Completed]

Bioequivalency Study of Zaleplon 10 mg Capsules Under Fed Conditions [Completed]

Bioequivalency Study of Zaleplon 10 mg Capsules Under Fasting Conditions [Completed]

Measurement of Cerebral Oxygen Extraction Fraction Using MRI Technique [Recruiting]

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