News related to Soma (Carisoprodol) and/or conditions it is approved for
New Chromosomal Abnormality Identified In Leukemia Associated With Down Syndrome
Source: Lymphoma / Leukemia / Myeloma News From Medical News Today [2009.10.19]
Researchers identified a new chromosomal abnormality in acute lymphoblastic leukemia (ALL) that appears to work in concert with another mutation to give rise to cancer. This latest anomaly is particularly common in children with Down syndrome. The findings have already resulted in new diagnostic tests and potential tools for tracking a patient's response to treatment. The research, led by scientists from St.
Antisoma's AS1411 Gains US And EU Orphan Drug Status For Acute Myeloid Leukaemia
Source: Lymphoma / Leukemia / Myeloma News From Medical News Today [2009.10.13]
Antisoma plc (LSE: ASM; USOTC: ATSMY) announces that its aptamer drug AS1411 has been granted orphan drug status in both the United States and the European Union for the treatment of acute myeloid leukaemia (AML). The grants will provide seven years of market exclusivity in the US and ten years of exclusivity in the EU if AS1411 is approved for use in AML. Positive phase II data for AS1411 in AML were presented at the 2008 ASH and 2009 ASCO meetings.
Antisoma To Amend ACCEDE Phase III Study Of AS1413
Source: Lymphoma / Leukemia / Myeloma News From Medical News Today [2009.10.08]
Antisoma announces that, following discussions with FDA and trial investigators, it plans to amend the primary endpoint in the ACCEDE study of AS1413. The ACCEDE study is an ongoing randomised, controlled phase III trial that compares AS1413 plus cytarabine with daunorubicin plus cytarabine in patients newly diagnosed with secondary acute myeloid leukaemia (secondary AML).
Sexual Abuse Linked to Somatic Disorders (CME/CE)
Source: MedPage Today Emergency Medicine [2009.08.19]
Sexual abuse is associated with an increased risk of somatic disorders, in which patients report physical symptoms or complaints with no clear underlying cause, a review of nearly two dozen studies concluded.
Is Somatic Hypersensitivity A Predictor Of Irritable Bowel Syndrome?
Source: Irritable-Bowel Syndrome News From Medical News Today [2009.07.23]
Although visceral hypersensitivity is considered a hallmark feature of IBS, conflicting evidence exists regarding somatic hypersensitivity in this patient population. Several investigators have found no evidence for heightened somatic pain sensitivity in IBS patients. Also, others have reported similar cold presser pain tolerance in IBS patients and controls. These conflicting findings may result from differing somatic pain testing procedures.
Gastrocor(R) Introduces New FISH Test For Colorectal Cancer Detection
Source: Colorectal Cancer News From Medical News Today [2009.11.02]
GastroFISH™ is the first tissue-based fluorescence in situ hybridization (FISH) test for the detection of chromosomal anomalies associated with colon cancer. "We are excited to be the first laboratory to offer GastroFISH for the colon. Using current histological techniques, identifying adenomas with a high risk for progression to cancer is not possible.
News From The American Journal Of Pathology, November 2009
Source: Allergy News From Medical News Today [2009.10.21]
A group led by Dr. Dieter Brömme at the University of British Columbia has demonstrated that glycosaminoglycans (GAGs) contribute to skeletal abnormalities in patients with lysosomal storage diseases. Their report can be found in the November 2009 issue of The American Journal of Pathology. Mucopolysaccharidoses (MPS) are a group of diseases in which the dysfunction of a lysosomal enzyme results in decreased breakdown of GAGs, a type of carbohydrate, in various tissues.
Schizophrenia And Bipolar Disorder Share Genetic Roots
Source: Bipolar News From Medical News Today [2009.07.04]
A trio of genome-wide studies - collectively the largest to date - has pinpointed a vast array of genetic variation that cumulatively may account for at least one third of the genetic risk for schizophrenia. One of the studies traced schizophrenia and bipolar disorder, in part, to the same chromosomal neighborhoods. "These new results recommend a fresh look at our diagnostic categories," said Thomas R. Insel, M.D.
Ultraviolet B light exposure increases risk of skin cancer
Source: The Doctors Lounge - Dermatology
Inability to repair chromosomal damage caused by UV-B radiation increases risk of basal cell and squamous cell carcinomas.
Muscle Spasms
Source: MedicineNet Amyotrophic Lateral Sclerosis Specialty [2009.06.17]
Title: Muscle Spasms
Category: Diseases and Conditions
Created: 6/16/2009
Last Editorial Review: 6/17/2009
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