Skelid (Tiludronate Disodium) - Summary

SKELID SUMMARY

SKELID®
(tiludronate disodium)

SKELID is a bisphosphonate characterized by a (4-chlorophenylthio) group on the carbon atom of the basic P-C-P structure common to all bisphosphonates. Its generic name is tiludronate disodium. Tiludronate disodium is the hydrated hemihydrate form of the disodium salt of tiludronic acid.

SKELID is indicated for treatment of Paget's disease of bone (osteitis deformans).

Treatment is indicated in patients with Paget's disease of bone (1) who have a level of serum alkaline phosphatase (SAP) at least twice the upper limit of normal, or (2) who are symptomatic, or (3) who are at risk for future complications of their disease.

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SKELID NEWS HIGHLIGHTS

Media Articles Related to Skelid (Tiludronate)

Paget's Disease
Source: MedicineNet calcitonin Specialty [2008.01.28]

Paget's Disease of The Nipple
Source: MedicineNet Breast Lumps In Women Specialty [2006.02.22]

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Published Studies Related to Skelid (Tiludronate)

Efficacy of tiludronate in the treatment of horses with signs of pain associated with osteoarthritic lesions of the thoracolumbar vertebral column. [2007.03]

Comparative pharmacokinetics of two intravenous administration regimens of tiludronate in healthy adult horses and effects on the bone resorption marker CTX-1. [2008.04]

Treatment with tiludronate has a similar effect to risedronate on Paget's disease activity assessed by bone markers and bone scintigraphy. [2007.03]

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